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19 Possible Causes for Apathy, Hyperreflexia, Nocturnal Leg Cramp

  • Hypoglycemia

    Feeling of numbness, pins and needles (paresthesia) Negativism, irritability, belligerence, combativeness, rage Personality change, emotional lability Fatigue, weakness, apathy[en.wikipedia.org]

  • Chronic Kidney Insufficiency

    […] filtration rate [eGFR] 15 mL/min/1.73 m 2 ), neuromuscular symptoms may be present, including coarse muscular twitches, peripheral sensory and motor neuropathies, muscle cramps, hyperreflexia[merckmanuals.com]

  • Graves Disease

    […] measurement of vitals is rate of percieved exertion. [4] Percautions/Symptoms related to hypothyroidism (if patient on medication or post surgical) [4] Excessive fatigue and apathy[physio-pedia.com] HLA-B8, Dr3 association Often incited during stress e.g. childbirth, infection, steroid withdrawal Presentation Symptoms heat intolerance weight loss hyperactive diarrhea hyperreflexia[step2.medbullets.com] Additional symptoms associated with Graves’ disease include heart palpitations, slight tremors of the hands and/or fingers, hair loss, brittle nails, exaggerated reflexes (hyperreflexia[rarediseases.org]

  • Pernicious Anemia

    […] impaired ability to coordinate movement (ataxia), a positive Babinski sign (outward motion of the big toe caused by stroking the sole of the foot), and/or exaggerated reflexes (hyperreflexia[rarediseases.org] Pernicious Anemia Macrocytic anemia, glossitis, peripheral neuropathy, weakness, hyperreflexia, ataxia, and other neurological manifestations characterize classical vitamin[clinlabnavigator.com] Vitamin B12 deficiency may present with any combination of the following: macrocytic anemia, glossitis (painful inflammation of the tongue), peripheral neuropathy, weakness, hyperreflexia[mayomedicallaboratories.com]

  • Insulinoma

    Neuroglycopenic symptoms include dizziness, confusion, apathy, amnesia, personality and behavioral changes, visual disturbances, seizure, and coma. 2 The diagnosis of insulinoma[journals.lww.com]

  • Hyperthyroidism

    Table 1 Psychiatric symptoms seen with hyperthyroidism Anxiety Apathy (more often seen in older patients) Cognitive impairment Delirium Depression Emotional lability Fatigue[mdedge.com] […] despite a voracious appetite Irritability Poor sleep Hypertension Proptosis with lid retraction and stare Warm, flushed skin Microcephaly with craniosynostosis Frontal bossing Hyperreflexia[clinicaladvisor.com]

  • Amyotrophic Lateral Sclerosis

    These patients and their carer/spouse were asked to report any history of abulia-apathy, hallucination, personality change and other variety of symptoms.[ncbi.nlm.nih.gov] If upper motor neurons are also damaged, spasticity and hyperreflexia and pathologic reflexes, such as Babinski’s sign, can also be observed.[flexikon.doccheck.com] FDA bans quinine for nocturnal leg cramps. Drug Utilization Rev. 1995; Oct:150. 26. Moss AH, Casey P, Stocking CB, Roos RP, Brooks BR, Siegler M.[aafp.org]

  • Parkinson's Disease

    Apathy was identified in 31.6%; apathy without depression was present in 33.3% of patients.[ncbi.nlm.nih.gov] Although no single sign distinguished the groups, patients with mutations had significantly earlier and more symmetrical onset, dystonia more often at onset and hyperreflexia[ncbi.nlm.nih.gov] ., mental retardation/dementia [14/29], psychosis [15/29], dystonia [11/29], and hyperreflexia [11/29]).[ncbi.nlm.nih.gov]

  • Hypocalcemia

    […] hemolysis Inadequate Potassium Excretion - from decreased aldosterone related to Adrenalectomy or Addison’s disease Signs of Hyperkalemia - High Potassium Diarrhea LOC Changes -Apathy[web.archive.org] Severe hypocalcemia with serum calcium 7 mg/dL ( 1.75 mmol/L) may cause hyperreflexia, tetany, laryngospasm, or generalized seizures.[merckmanuals.com] Hyperreflexia. Other symptoms and signs depend on the aetiology: DiGeorge's syndrome : Recurrent infections due to T-cell immunodeficiency.[patient.info]

  • Hypomagnesemia

    Mental status changes include mood alterations such as apathy, depression, or apprehension; confusion; hallucinations; delirium; or psychosis.[nursingcenter.com] Symptoms include anorexia, nausea, vomiting, lethargy, weakness, personality change, tetany (eg, positive Trousseau or Chvostek sign, spontaneous carpopedal spasm, hyperreflexia[merckmanuals.com] .  Other manifestations include Apathy, Muscle cramps, Hyperreflexia, Acute organic brain syndromes, Depression, Generalized weakness, Anorexia, Vomiting 34.  Measurement[slideshare.net]

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