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25 Possible Causes for Apathy, Prominent Sulci

  • Alcohol Dementia

    ARD patients often have symptoms of both forms, i.e. impaired ability to plan, apathy, and memory loss. ARD may occur with other forms of dementia (mixed dementia).[] The CT showed prominent sulci and gyri with deep white matter changes. There were no other abnormalities.[] Symptoms of Wernicke-Korsakoff syndrome include confusion, apathy, hallucinations, communication problems, problems with learning new information and severe memory impairment[]

  • Normal Pressure Hydrocephalus

    Among 46 patients with suspicion of iNPH (77.6 6.7years; 34.8% women), 30 (65.2%) presented apathy (defined by a score 14 on the Starkstein apathy scale).[] NPH is suggested when ventricular dilation is out of proportion to the prominence of the sulci, but this is a subjective call.[] Methylphenidate produced a dose-dependent positive improvement in behavioural measures in the patient associated with a reduction in apathy.[]

  • AIDS-associated Meningoencephalitis

    While there is some individual variation, frequent manifestations include: inattention and reduced concentration, apathy and dulling of personality, psychomotor slowing, marked[] MRI of the brain showed some effacement of cortical sulci, rendering the vessels prominent, with increased T2-weighted signal diffusely scattered throughout both hemispheres[]

  • Creutzfeldt Jakob Disease

    Whether symptoms develop gradually or abruptly, mental decline progresses, often producing such symptoms as neglect of personal hygiene, apathy, and irritability.[] B, Corresponding FLAIR image shows marked prominence of ventricles and sulci for the patient’s age.[] Clinical features Early in the illness, patients usually experience psychiatric or sensory symptoms, which most commonly take the form of depression, apathy or anxiety, and[]

  • West Nile Encephalitis

    Arrows indicate subtle enhancement in the sulci. B and C, FLAIR images show increased signal intensity in the sulci, more prominent on the left than on the right.[]

  • Kwashiorkor

    […] impoverished regions that is characterized by failure to grow and develop, changes in the pigmentation of the skin and hair, edema, fatty degeneration of the liver, anemia, and apathy[] , prominence of basal cisterns, and ventricular dilation resulting in cerebral atrophy, as well as periventricular white matter (PVWM).[] Early signs include apathy, drowsiness, and irritability.[]

  • Semantic Dementia

    In contrast, patients with bvFTD demonstrated pronounced deficits in attention/working memory, increased apathy and greater executive dysfunction, compared to patients with[] Memory deficit; presents early in the dz course Imaging with CT or MRI shows diffuse cortical atrophy with prominent sulci and compensatory ventricular dilation; parietal[] […] dementia include: behaviour and personality changes difficulty spelling and pronouncing words accurately difficulty recognising people addictive or compulsive behaviour apathy[]

  • Pick Disease of The Brain

    Apathy is often mistaken for depression.[] Characteristic features include prominent cerebral sulci (i.e. cortical atrophy) and v entriculomegaly (i.e. central atrophy) without bulging of the third ventricular recesses[] […] interaction Emotional changes: Sudden mood swings Decreased concern for daily activities Inability to recognize behavioral changes Failure to show empathy Inappropriate mood Apathy[]

  • Cerebral Cortical Atrophy

    Neuropsychiatric features, oculomotor dysfunction and sleep disturbances are also observed in MSA and include apathy, anxiety, depression, rapid eye movement sleep behavior[] Imaging wise feature of cerebral cortical atrophy Generalized prominence of hemisphere cortical sulci on CT or MRI in mild cases.[] Apathy or depression occur about as often as with AD.[]

  • Marchiafava Bignami Disease

    After regaining consciousness, she presented with lack of movement, apathy, labile affect, and poverty of speech.[] Findings CT shows mild prominence of the ventricles and sulci consistent with mild generalized cerebral volume loss.[] […] routine chemistry, autoimmune profile, viral serology, vitamin B12, toxicology screen, and CSF examination were all normal.Six weeks later he was admitted because of worsening apathy[]

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