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15 Possible Causes for Apathy, Severe Recurrent Orthostatic Hypotension

  • Syncope

    However, a syncopal episode associated with normal sinus rhythm may be due to several disorders such as orthostatic hypotension, vasovagal or carotid sinus reflexes, or even[omicsonline.org] […] syncope. 54 ORTHOSTATIC HYPOTENSION Treatment of orthostatic hypotension includes education and lifestyle modifications, such as slowly transitioning from a supine or sitting[aafp.org] ILRs can be considered for elderly patients (7th and 8th decades) with recurrent and troublesome syncope; however, they have only been shown to improve care in a subset of[omicsonline.org]

  • Orthostatic Syncope

    Neuropsychiatric features, oculomotor dysfunction and sleep disturbances are also observed in MSA and include apathy, anxiety, depression, rapid eye movement sleep behavior[orpha.net] Although symptom recurrence on follow-up was lower in patients with more severe orthostatic hypotension, the clinical significance of this finding needs to be further defined[ncbi.nlm.nih.gov] Effects of orthostatic hypotension on cognition in Parkinson disease. Neurology 2017, 88:17-24 Connolly S and others.[dizziness-and-balance.com]

  • Hypotension

    Along with apathy with retained cognition, he had stable ataxia, impaired upgaze and episodes of central apnoea.[ncbi.nlm.nih.gov] Effects of orthostatic hypotension on cognition in Parkinson disease. Neurology 2017, 88:17-24 Connolly S and others.[dizziness-and-balance.com] Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope. Jama 2003:289:2224-2229 Freeman R, Young J, Landsberg L, Lipsitz L.[dizziness-and-balance.com]

  • Acute Pandysautonomia

    Patient 9 showed memory disturbances and apathy in daily living, such as domestic duties.[journals.plos.org] Patient 6 had a history of recurrent ileus and severe abdominal pain.[journals.plos.org] Illustrative cases Patient 1: A 75-year-old man who had been affected by AAG for at least 15 years and who had severe orthostatic hypotension (supine, 102/64 mmHg; sitting[journals.plos.org]

  • Amyloidosis

    In: Amyloid and Amyloidosis: The Proceedings of the IXth International Symposium on Amyloidosis, Budapest, David Apathy, 2001, pp 116 –118 Ericzon BG, Larsson M, Herlenius[doi.org] Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org] Patients with recurrent syncope may require permanent pacemaker implantation, and ventricular arrhythmias usually are treated with amiodarone and, in some patients, implantable[doi.org]

  • Pure Autonomic Failure

    Clinical correlates of apathy in patients recently diagnosed with Parkinson s disease: the ANIMO study. Neuroepidemiology 2012 Jan. PMID: 22236943.[neurotek.es] First, patients with PAF did not have severe urinary disturbances, which would lessen the risk of recurrent urinary infections, and they also did not have life threatening[jnnp.bmj.com] Impact of apathy on health-related quality of life in recently diagnosed Parkinson s disease: the ANIMO study. Mov Disord 2012 Feb. PMID: 21780179.[neurotek.es]

  • Systemic Amyloidosis

    . & Apathy, A.) 589–592 (2001). 112. Dember, L. et al . Eprodisate for the treatment of renal disease in AA amyloidosis . N. Engl. J. Med. 356 , 2349–2360 (2007). 113.[nature.com] recurrent inflammation. 57 Supportive treatment of specific symptoms Although symptoms of dysautonomia are rare in AA amyloidosis, severe orthostatic hypotension may lead[ncbi.nlm.nih.gov] Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    In some people with HSAN IE, changes in personality, such as irritability, apathy, or lack of impulse control, become apparent before problems with thinking skills.[ghr.nlm.nih.gov] Severe autonomic dysfunctions occur: alacrymia (loss of tear secretion), dysphagia, hypothermia, orthostatic hypotension, loss of fungiform papillas on tongue.[tankonyvtar.hu] Gastroesophageal reflux, vomiting or recurrent pneumonia indicate gastrointestinal dysfunction. Sensory loss is mild; scoliosis frequently develops (85%). 2.4.[tankonyvtar.hu]

  • Serum Neuropathy

    Additionally, these patients frequently have symptoms of anxiety, depression and apathy. [1] [4] [5] [6] [8] [10] [23] [27] [28] Signs No clinical findings are generally seen[eyewiki.aao.org] Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[cjasn.asnjournals.org] Patients with recurrent syncope may require permanent pacemaker implantation, and ventricular arrhythmias usually are treated with amiodarone and, in some patients, implantable[cjasn.asnjournals.org]

  • Familial Dysautonomia

    An infant presented with congenital hypotonia, poor sucking, apathy, and areflexia.[ncbi.nlm.nih.gov] The latter leads to severe hypotension and may later trigger syncopes due to orthostatic hypotension.[symptoma.com] ) and gastrostomy tube placement; labile BP with orthostatic hypotension, supine hypertension, and several hypertensive crises per week; syncopal episodes necessitating pacemaker[cjasn.asnjournals.org]

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