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110 Possible Causes for Apathy, Tryptophan Increased

  • Endogenous Depression

    It also includes apathy and almost constant crying. The third category is an impact on a person's feelings.[wisegeek.com] increases the production of serotonin, three doses per week of this simple low-cost solution effectively protect me from serotonin deficient depression.[balancingbrainchemistry.co.uk] Thoughts: Lack of concentration Forgetfulness Inability to make spontaneous decisions Pessimistic attitude Guilt Self pity Thoughts of self destruction Impact on your Behavior: Apathy[depressivedisorder.blogspot.com]

  • Reactive Depression

    Apathy is often prominent when depression emerges during AD’s middle stage, though classic depressive symptoms such as agitation, crying, the inability to experience pleasure[brightfocus.org] increases the production of serotonin, three doses per week of this simple low-cost solution effectively protect me from serotonin deficient depression.[balancingbrainchemistry.co.uk] Antidepressants however not the only way to raise serotonin there is evidence that raising the level of tryptophan (the amino acid that serotonin is made from) in the brain[balancingbrainchemistry.co.uk]

  • Alzheimer Disease

    Apathy represents a form of executive cognitive dysfunction.[ncbi.nlm.nih.gov] Cerebrospinal analysis was consistent with AD pattern, with decreased Aβ42 and increased Tau and phospho-Tau.[ncbi.nlm.nih.gov] Koopmans, A Comparative Validation of the Abbreviated Apathy Evaluation Scale (AES-10) With the Neuropsychiatric Inventory Apathy Subscale Against Diagnostic Criteria of Apathy[dx.doi.org]

  • Hepatic Encephalopathy

    Criteria Grade 0 No signs or symptoms Grade 1 Trivial lack of awareness Euphoria or anxiety Shortened attention span Impaired performance of addition Grade 2 Lethargy or apathy[aafp.org] Benzodiazepine-like compounds have been detected at increased levels as well as abnormalities in the GABA neurotransmission system.[en.wikipedia.org] People you live with should be aware that HE can be the cause of irritability, memory loss, apathy, and even change in personality and violence.[pscsupport.org.uk]

  • Acute Amphetamine Intoxication

    Emotional states commonly associated with these shifts in consciousness include confusion, anxiety, euphoria, agitation, depression, anger, irritability, and apathy.[addiction.com] 5-HT1A receptor activity (like lithium, meperidine, or tryptophan), monoamine oxidase inhibitors (MAOIs), or selective serotonin reuptake inhibitors (SSRI) with the ingestion[calsprogram.org] Inhalants Mechanism unknown Intoxication presentation belligerence, assaultiveness apathy, impaired judgement blurred vision, coma treatment no specific treatment antipsychotics[medbullets.com]

  • Dementia

    Apathy, depression, irritability, agitation, and anxiety are the most frequently detected neuropsychiatric symptoms of AD.[ncbi.nlm.nih.gov] In Alzheimer's dementia, there are reduced levels of serotonin and its precursors such as tryptophan [ 5 ].[doi.org] A 42-year-old woman presented with a 6-month history of diffuse headache of moderate intensity and gradual onset of generalized weakness, imbalance, apathy, memory decline[ncbi.nlm.nih.gov]

  • Postpartum Depression

    […] difficulty concentrating and making decisions low self-confidence poor appetite (not eating enough) feeling very agitated or, alternatively, you can’t be bothered with anything (apathy[tommys.org] Prenatal depressive symptoms are associated with exaggerated pregnancy-specific changes in IO&NS pathways, including increased C-reactive protein, advanced oxidation protein[ncbi.nlm.nih.gov] Agitation or apathy. Guilt. Feelings of worthlessness. Inability to concentrate. Headaches. Panic attacks. Lack of feeling for the baby. Fantasies of hurting the baby.[web.archive.org]

  • Mental Disorder

    […] sclerosis) , or Lou Gehrig’s disease Parkinson’s disease all forms of dementia Some of the more common symptoms of neurodegenerative diseases include: memory loss forgetfulness apathy[healthline.com] As discussed earlier, the amino acid tryptophan is a precursor to serotonin, and tryptophan supplements (which are better than 5-Hydroxytryptophan) will increase serotonin[doi.org] But then the anger, agitation, even apathy, and sympathy are also being amplified. That’s how an “up” day feels.[atlassian.com]

  • Drug Dependence

    The link between dopamine function and apathy in cannabis users: an [18F]-DOPA PET imaging study.[doi.org] There is evidence that bingeing on sugar-dense, palatable foods increases extracellular dopamine in the striatum and thereby possesses addictive potential.[ncbi.nlm.nih.gov] Drugs such as cocaine and methamphetamine are associated with severe emotional withdrawal symptoms such as depression and apathy, and people may be at risk for accidents due[projectknow.com]

  • Pellagra

    At the same time, there was noticeable improvement in the patient's depression and apathy.[ncbi.nlm.nih.gov] Investigation of urinary tryptophan metabolites following an oral tryptophan load, showed increased excretion of kynurenine and kynurenic acid but reduced excretion of 3-hydroxy-kynurenine[ncbi.nlm.nih.gov] These are commonly seen as irritability, poor concentration, anxiety, fatigue, restlessness, apathy and depression.[ncbi.nlm.nih.gov]

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