Aphthous Stomatitis: Causes & Reasons

Possible Causes for Aphthous Stomatitis

Aphthous stomatitis is an illness that causes small ulcers to appear in the mouth, usually inside the lips, on the cheeks, or on the tongue. [chop.edu]

aphthous stomatitis.[5] It is termed major aphthous ulceration (MaAU) or major recurrent aphthous stomatitis (MaRAS). [en.wikipedia.org]

stomatitis. [statpearls.com]

Gingivostomatitis

Abstract It is thus apparent from the results of various studies that the conditions called aphthous ulcer (canker sore), herpes labialis, aphthous stomatitis, herpetic stomatitis [ajodo.org]

aphthous stomatitis; episode frequency associated with recurrent aphthous stomatitis; and safety of the intervention including adverse effects. [doi.org]

Periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome—occurs in children. [en.wikipedia.org]

Aphthous Stomatitis

Synonym(s): aphthae minor, aphthous stomatitis, canker sores, recurrent aphthous stomatitis, recurrent aphthous ulcers, recurrent ulcerative stomatitis, ulcerative stomatitis [medical-dictionary.thefreedictionary.com]

[…] childhood, that affects up to 25% of the general population. 1 Minor aphthous stomatitis is the most common form, affecting 80% of patients with aphthous stomatitis, and consists [cmaj.ca]

Crossover study of thalidomide versus placebo in severe recurrent aphthous stomatitis. Arch Dermatol 1990;118;923-927. [healthmantra.com]

Herpes Simplex Gingivostomatitis

The differential diagnosis of PHG includes acute necrotizing ulcerative gingivitis, herpangina, aphthous stomatitis, candidiasis of the mouth, Steven-Johnson syndrome and [smile-onnews.com]

It includes but is not limited to trauma, recurrent aphthous stomatitis (commonly known as “canker sores”), syphilis, viral, zoster, erythema multiforme, cyclic neutropenia [journals.lww.com]

The differential diagnosis of primary herpetic gingivostomatitis has been reviewed in the differential diagnosis of recurrent aphthous stomatitis. [softdental.com]

Recurrent Oral Ulceration

[…] of aphthous stomatitis. [5] It is termed major aphthous ulceration (MaAU) or major recurrent aphthous stomatitis (MaRAS). [en.wikipedia.org]

Recurrent Aphthous Stomatitis: A Review. [biomedpharmajournal.org]

Recurrent aphthous stomatitis. Quintessence Int 2000;31:95-112. 14. Ship JA. Recurrent aphthous stomatitis. An update. [ijmdent.com]

Radiation Stomatitis

The appearance of aphthous stomatitis varies as there are 3 types, namely minor aphthous ulceration, major aphthous ulceration and herpetiform ulceration. [fr.bab.la]

Aphthous stomatitis treatment Medical treatment is usually not necessary for aphthous stomatitis, unless the ulcers are severe (larger than one centimeter or lasting longer [encyclopedia.com]

Aphthous stomatitis, also known as recurrent aphthous ulcers (RAU) or canker sores, is a specific type of stomatitis that presents with shallow, painful ulcers that are usually [medical-dictionary.thefreedictionary.com]

Behçet Disease

aphthous stomatitis.[5] It is termed major aphthous ulceration (MaAU) or major recurrent aphthous stomatitis (MaRAS). [en.wikipedia.org]

A 47-year-old male patient had 10-years history of recurrent aphthous stomatitis and genital ulcer. [doi.org]

Behçet's syndrome (BS; Adamantiades syndrome) is the association of the triple symptom complex of recurrent aphthous stomatitis (RAS) with genital ulceration, and eye disease [ncbi.nlm.nih.gov]

Herpes Labialis

aphthous stomatitis.[5] It is termed major aphthous ulceration (MaAU) or major recurrent aphthous stomatitis (MaRAS). [en.wikipedia.org]

The prevalence was related to the place of living, income, and college, but not to gender, marital status, medical history, smoking, or aphthous stomatitis. [ncbi.nlm.nih.gov]

stomatitis Herpes gingivostomatitis Herpes labialis Measles (Koplik's spots) Perioral dermatitis Oral thrush Steven Johnson syndrome Streptococcal pharyngitis Tongue diagnoses [wikem.org]

Cyclic Neutropenia

Recurrent aphthous stomatitis with a periodicity of around 3 weeks should alert the dermatologist to the possibility of cyclic neutropenia. [ncbi.nlm.nih.gov]

Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome is linked to dysregulated monocyte IL-1β production. [piv.or.kr]

In another patient, aphthous stomatitis disappeared but fever persisted. The duration of neutropenia was prolonged and submaxillaritis and sinusitis occurred. [ncbi.nlm.nih.gov]

Primary Herpes Simplex Infection

The differential diagnosis of primary herpetic gingivostomatitis has been reviewed in the differential diagnosis of recurrent aphthous stomatitis. [softdental.com]

RIH may appear similar to traumatic lesions (mechanical/thermal/chemical) or other types of oral mucosal disorders, such as aphthous stomatitis. [jcda.ca]

[…] canker sores (aphthous ulcers). [medicinenet.com]

Mevalonate Kinase Deficiency

stomatitis) Suggested criteria for diagnosis and classification (Mevalonate kinase deficit) (Federci, S, PRINTO / Eurofever 2015) Occurrence Points Debut age during 2 years [bindevevssykdommer.no]

Fifteen percent of the patients had aphthous stomatitis independent of fever. [onlinelibrary.wiley.com]

Tasher D, Stein M, Dalal I et al (2008) Colchicine prophylaxis for frequent periodic fever, aphthous stomatitis, pharyngitis and adenitis episodes. [link.springer.com]

Celiac Disease

Recurrent aphthous stomatitis was reported in 26 patients (53.0%) and in 13 (25.5%) controls ( p = 0.005). [ncbi.nlm.nih.gov]

There are conflicting data on the association between CD and recurrent aphthous stomatitis. [ncbi.nlm.nih.gov]

stomatitis, angular cheilitis, and dental enamel defects in primary and permanent teeth.5 The dental enamel defects are often a result of hypoplasia, and most commonly occur [ada.org]

Pemphigus

The differential diagnosis of acute herpetic stomatitis and recurrent aphthous stomatitis was suggested. [jdrr.org]

Akintoye SO, Greenberg MS (2005) Recurrent aphthous stomatitis. Dent Clin North Am 49: 31-47, vii-viii. [autoimmunediseases.imedpub.com]

Disease or condition Clinical characteristics Recurrent aphthous stomatitis Appearance of ulcers (aphthae) in oral mucosa with yellowish base, surrounded by an erythematous [omicsonline.org]

Chemotherapy-induced Mucositis

[…] erythematous halo, and they appear clinically identical to idiopathic aphthous stomatitis in otherwise healthy patients. [emedicine.medscape.com]

stomatitis (Al‐Dasooqi 2013; Boers‐Doets 2013; Peterson 2015). [cochranelibrary.com]

Also, indicated for diffuse aphthous ulcers. [gelclair.com]

Lichen Planus

BACKGROUND: In spite of all the efforts, recurrent aphthous stomatitis (RAS) and oral lichen planus (OLP) still have unexplained etiology. [ncbi.nlm.nih.gov]

stomatitis and oral lichen planus, Journal of Oral Pathology & Medicine, 43, 6, (410-417), (2014). [doi.org]

Furthermore, OLP seems to have a higher impact on patients’ quality of life than recurrent aphthous stomatitis but lower impact as compared to oral bullous diseases [ 280 [hindawi.com]

Childhood Celiac Disease

Disease Dilated (congestive) Cardiomyopathy – inflammation of heart muscle Alopecia Areata – patchy hair loss Rheumatoid Arthritis Fibromyalgia Collagen-Vascular Disease Aphthous [childrensnational.org]

stomatitis – canker sores Multiple Sclerosis Systemic Lupus Erythematosis Reynaud’s Syndrome – constriction of blood vessels of hands, feet, fingers and toes Behavioral/Psychiatric [childrensnational.org]

stomatitis defects in dental enamel vitamin deficiencies osteoporosis other autoimmune endocrine disorders, such as thyroiditis neurological symptoms, including ataxia and [medicalhomeportal.org]

Erythema Multiforme

Oral lesions must be distinguished from aphthous stomatitis, pemphigus, herpetic stomatitis, and hand-foot-and-mouth disease. [merckmanuals.com]

• In the presence of oral lesions, – Aphthous stomatitis, – Contact dermatitis or stomatitis – Acute necrotizing gingivitis – Pemphigus, – Dermatitis herpetiformis, – Bullous [slideshare.net]

Reiter Syndrome

In the oral cavity, the patients may suffer from recurrent aphthous stomatitis, geographic tongue and migratory stomatitis in higher prevalence than the general population [en.wikipedia.org]

Pernicious Anemia

The aim of this report is to present the management of a patient with pernicious anemia afflicted with recurrent aphthous stomatitis (RAS). [ncbi.nlm.nih.gov]

PFAPA Syndrome

Abstract Adult‐onset periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is rare. [onlinelibrary.wiley.com]

Syndrome of periodic fever, pharyngitis, and aphthous stomatitis. J Pediatr 1987; 110: 43–46. [nature.com]

The first international conference on periodic fever, aphthous stomatitis, pharyngitis, adenitis syndrome. [frontiersin.org]

Marshall Syndrome

Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). [saidsupport.org]

PFAPA Periodic Fever, Aphthous stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) is also known as Marshall Syndrome. [autoinflammatory.org]

Marshall's syndrome is characterized by the appearance of a periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis in children. [symptoma.com]

Secondary Syphilis

These were wrongly diagnosed as 'aphthous stomatitis' and treated with betamethasone gargling. [ijdvl.com]

stomatitis. [ijdvl.com]

Recurrent mucosal erosions in the mouth she developed subsequently as manifestation of relapsing secondary syphilis were wrongly diagnosed as 'aphthous stomatitis' and were [ijdvl.com]

Herpes Simplex Esophagitis

Exam showed cachexia/temporal wasting, aphthous stomatitis and abdominal tenderness. [ncbi.nlm.nih.gov]

Physical exam was significant for cachexia, temporal wasting, aphthous stomatitis involving the tongue and diffuse abdominal tenderness. [ncbi.nlm.nih.gov]

Relapsing Polychondritis

stomatitis 0011107 Renal insufficiency Renal failure Renal failure in adulthood [ more ] 0000083 Scleritis 0100532 Sensorineural hearing impairment 0000407 Thrombophlebitis [rarediseases.info.nih.gov]

stomatitis Recurrent canker sores 0011107 Renal insufficiency Renal failure Renal failure in adulthood [ more ] 0000083 Scleritis 0100532 Sensorineural hearing impairment [rarediseases.info.nih.gov]

[…] area of skin 0012733 Myocarditis 0012819 Proteinuria High urine protein levels Protein in urine [ more ] 0000093 Purpura Red or purple spots on the skin 0000979 Recurrent aphthous [rarediseases.info.nih.gov]

Gingivosis

Read more » Canker Sores (Aphthous Stomatitis Or Recurrent Mouth Ulcers) This disease causes painful, round ulcers to develop on the linings of the cheeks and lips, the tongue [colgateprofessional.com]

Drug Hypersensitivity

stomatitis Bullous pemphigoid Granulomatous disorders such as sarcoidosis Pyoderma gangrenosum Sweet disease Pityriasis lichenoides chronica. [dermnetnz.org]

Doxycycline is also effective at controlling non-infectious, inflammatory skin and mucosal diseases, including: Acne Rosacea Perioral dermatitis Hidradenitis suppurativa Recurrent aphthous [dermnetnz.org]

Inflammatory Bowel Disease Type 1

Arthritis Erythema nodosum Pyoderma gangrenosum Aphthous stomatitis Iritis/uveitis Table 2 Autoimmune disorders associated to IBD. [doi.org]

Aphthous stomatitis is more common in patients with CD (20–30%) than in those with UC (5–10%) (3). [tp.amegroups.com]

stomatitis 35 joints arthritis seronegative spondyloarthritis sacroiliitis (one of the most frequent extraintestinal manifestations) eyes episcleritis iritis uveitis (acute [radiopaedia.org]

Sjögren Syndrome

Vitamin B12 deficiency is a well-known cause of recurrent aphthous stomatitis, although the mechanism by which this deficiency causes the stomatitis is not well understood [oatext.com]

Aphthous Denture-related Herpetic Smokeless tobacco keratosis Submucous fibrosis Ulceration Riga–Fede disease Verruca vulgaris Verruciform xanthoma White sponge nevus Teeth [en.wikipedia.org]

Vitamin B12 therapy led to an immediate resolution of aphthous stomatitis and full correction of neutrophil function [10]. [oatext.com]

Chronic Granulomatous Disease

He also had recurrent otitis media, tonsillitis, and aphthous stomatitis. [wwwnc.cdc.gov]

stomatitis, pyoderma gangrenosum, and vasculitis-like skin rash on face and limbs. [bloodjournal.org]

[…] osteomyelitis and septic arthritis, suppurative adenitis, liver cysts and calcified lesions (detected by computerized tomography), pan-uveitis, anthralgia, vaginal ulcers, aphthous [bloodjournal.org]

Immune System Disorder

stomatitis, pharyngitis and adenitis PGM3-CDG Poikiloderma with neutropenia Pruritic urticarial papules plaques of pregnancy Purine nucleoside phosphorylase deficiency Pyogenic [rarediseases.info.nih.gov]

[…] recessive 7 Palindromic rheumatism Papillon Lefevre syndrome Partial androgen insensitivity syndrome PASLI disease Pearson syndrome Pediatric multiple sclerosis Periodic fever, aphthous [rarediseases.info.nih.gov]