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526 Possible Causes for Aplastic Anemia, Bilirubin Increased

  • Paroxysmal Nocturnal Hemoglobinuria

    The frequency of PNH clone detected in aplastic anemia and non-aplastic anemia groups was 12.02 and 3.36%, respectively.[ncbi.nlm.nih.gov] […] in total bilirubin concentrations (median 3.4 mg/dL; range 2.1-8.1 mg/dL) during chronic eculizumab treatment and normal/or slightly increased serum aminotransferase activities[ncbi.nlm.nih.gov] The median telomere length of aplastic anemia patients was -0.99 standard deviation (SD) (range -4.01- 3.01 SD).[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    An anonymous 17-question survey was emailed to members of the Myeloproliferative Neoplasm (MPN) Research Foundation database and Aplastic Anemia and MDS International Foundation[ncbi.nlm.nih.gov] […] leukocyte alkaline phosphatase , increased vit.B12 level, decreased folic acid level, elevated alk.phosphatase & conjungated bilirubin, hypercalcemia.[enotes.tripod.com] Hemoglobinopathy Spurious polycythemia LABORATORY Polycythemia with elevated Hgb, Hct, platelet counts, WBC, uric acid; decreased erythropoietin , bone marrow erythroid hyperplasia , increased[enotes.tripod.com]

  • Acute Liver Failure

    This observation, coupled with previous reports of both pediatric and adult liver transplant patients suffering aplastic anemia — a lack of blood cells caused by bone marrow[med.stanford.edu] Having survived severe septic shock and ARDS his condition has stabilised when suddenly his LFTs become deranged with ALT increases to 3402 U/L, AST to 5322 U/L, Bilirubin[intensivecarenetwork.com] Pancreatitis: 5% across all etiologies Bone marrow failure: Aplastic anemia in 1-2% of seronegative hepatitis and hemophagocytic syndrome in 5% What is the right therapy for[clinicaladvisor.com]

  • Systemic Candidiasis

    A 15 year old girl with aplastic anemia developed a heparin-like anticoagulant during the course of systemic candidiasis.[ncbi.nlm.nih.gov] One month after discontinuation of ketoconazole, the liver enzyme concentrations decreased; however, over the next five months, liver enzymes and bilirubin increased.[ncbi.nlm.nih.gov] . • Liver, kidney, hematology : Some patients, particular those with AIDS or malignancies, developed increased liver enzymes, bilirubin, AP, BUN, serum creatinine, eosinophilia[gilbertssyndrome.com]

  • Bone Marrow Transplant

    We report a case of Legionnaire disease in a 19-year-old male with aplastic anemia after bone marrow transplant, who was being treated in a children's hospital.[ncbi.nlm.nih.gov] His total bilirubin increased to 2.8 mg/dL, and his body weight increased by 15%. An abdominal ultrasound noted ascites and hepatomegaly without reversal of blood flow.[ncbi.nlm.nih.gov] A patient with atopic dermatitis (AD) underwent allogeneic BMT for idiopathic acquired aplastic anemia.[ncbi.nlm.nih.gov]

  • Ketoconazole

    Three consecutive cases of severe aplastic anemia undergoing immunosuppressive therapy with cyclosporin A (CyA) and high-dose methylprednisolone (HDMP) developed grand mal[ncbi.nlm.nih.gov] One month after discontinuation of ketoconazole, the liver enzyme concentrations decreased; however, over the next five months, liver enzymes and bilirubin increased.[ncbi.nlm.nih.gov] We found that burn increased creatinine, BUN, and total bilirubin levels, while burn was associated with decreased total protein levels.[journals.plos.org]

  • Hydrocortisone

    Corticosteroids are used to treat certain conditions that affect the immune system such as aplastic anemia (AA), Immune Thrombocytopenia Purpura (ITP), Thrombotic Thrombocytopenia[chemocare.com] Plasma total bilirubin was increased by 10% from 7 to 8 μM in response to the higher hydrocortisone dose (P 0·033).[ncbi.nlm.nih.gov] Bilirubin is modestly increased in response to higher glucocorticoid exposure in humans, in conjunction with lower alkaline phosphatase and aspartate aminotransferase activities[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    anemia ( D61.9 ) pancytopenia (due to) (with) bone marrow infiltration ( D61.82 ) pancytopenia (due to) (with) congenital (pure) red cell aplasia ( D61.01 ) pancytopenia[icd10data.com] Aplastic anemia This is a condition where there is loss or suppression of production of RBCs.[news-medical.net] […] myeloproliferative disease ( D47.1 ) ICD-10-CM Diagnosis Code D61.81 Pancytopenia 2016 2017 2018 2019 Non-Billable/Non-Specific Code Type 1 Excludes pancytopenia (due to) (with) aplastic[icd10data.com]

  • Chlorpromazine

    , aplastic anemia, thrombocytopenia Hepatic: jaundice, hepatitis Skin: rash, photosensitivity, pigmentation changes, sterile abscess Other: allergic reactions, hyperthermia[medical-dictionary.thefreedictionary.com] Hematological Disorders , including agranulocytosis , eosinophilia , leukopenia , hemolytic anemia , aplastic anemia , thrombocytopenic purpura and pancytopenia have been[rxlist.com] Hematologic: leukopenia, agranulocytosis, eosinophilia, hemolytic anemia, aplastic anemia, thrombocytopenia. Hepatic: jaundice.[glowm.com]

  • Hepatic Veno-Occlusive Disease

    anemia after conditioning with cyclophosphamide plus antithymocyte globulin.[uke.de] Patients may develop jaundice because of the increased bilirubin levels. If VOD is severe, weight gain and bilirubin levels increase at a faster rate.[voice.ons.org] Symptoms include enlarged liver, increased bilirubin and weight gain due to fluid retention.[drugs.com]

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