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37 Possible Causes for Aplastic Anemia, Cryoglobulinemia, Yellow Discoloration of the Skin

  • Chronic Hepatitis C

    Pancytopenia due to myelotoxicity caused by these drugs may occur, but severe hematological abnormalities or aplastic anemia (AA) have not been described.[ncbi.nlm.nih.gov] Approximately 80% of patients with hepatitis C virus infection develop chronic liver disease as cirrhosis, and 40% develop autoimmune complications as mixed cryoglobulinemia[ncbi.nlm.nih.gov] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org]

  • Viral Hepatitis

    HPV-B19 DNA has been found in liver samples from 67% of patients with non-A and non-E FHF and aplastic anemia, in 50% of patients with cryptogenic FHF without aplastic anemia[doi.org] HCV RNA can be demonstrated in the tumor as well as in surrounding liver tissue although HCV RNA cannot be integrated in the hepatocytic DNA. 3--Essential cryoglobulinemia[meddean.luc.edu] The most notable symptom of acute viral hepatitis is jaundice, which is a yellow discoloration of the skin and the whites of the eyes.[patients.gi.org]

  • Hepatitis B

    RESULTS: Clinical history, examinations, and laboratory results suggest HBV-associated cryoglobulinemia and vasculitis.[ncbi.nlm.nih.gov] Jaundice (a yellow discoloration of eyes and skin), which is usually a sign of liver damage, may not occur.[web.archive.org] Other disorders--essential mixed cryoglobulinemia and polymyalgia rheumatica--have also been linked to HBV, but these associations are more controversial.[ncbi.nlm.nih.gov]

  • Autoimmune Disease

    High-dose cyclophosphamide without stem cell rescue in 207 patients with aplastic anemia and other autoimmune diseases. Medicine (Baltimore) 90, 89–98 (2011). 33.[doi.org] Autoimmune diseases are the most frequently associated disorders and include rheumatoid arthritis, systemic lupus erythematosus, cryoglobulinemia, pemphigus vulgaris, and[ncbi.nlm.nih.gov] In severe cases the individual can develop a yellow discoloration to the skin and eyes known as jaundice.[primaryimmune.org]

  • Hepatitis G

    Hepatitis associated aplastic anemia (HAAA) is a variant of aplastic anemia in which aplastic anemia follows an acute attack of hepatitis.[ncbi.nlm.nih.gov] Hepatitis C virus (HCV) infection is associated with type II cryoglobulinemia.[ncbi.nlm.nih.gov] Hepatitis may occur with limited or no symptoms, but often leads to yellow discoloration of the skin, mucus membranes, and conjunctivae, poor appetite and malaise.[disabled-world.com]

  • Cold Agglutinin Disease

    anemia Clinical symptoms Pallor, excessive fatigue ;, weakness Intermittent jaundice and episodes of red/ dark urine Venous thrombosis in unusual locations (e.g., hepatic[amboss.com] Rituximab therapy has been found to be effective in mixed cryoglobulinemia, with decreases in cryoglobulin values and improvement in complement values.[ncbi.nlm.nih.gov] Some people experience fatigue and jaundice yellowing of the skin and/or the whites of the eyes.[sunridgemedical.com]

  • Infectious Mononucleosis

    Infectious mononucleosis (IM) is a rare cause of aplastic anemia in adults.[ncbi.nlm.nih.gov] Arima, Mami Tamai, Satoshi Yamasaki, Hideki Nakamura, Hiroyuki Moriuchi and Atsushi Kawakami, An elderly patient with chronic active Epstein–Barr virus infection with mixed cryoglobulinemia[oadoi.org] skin.[hopkinsmedicine.org]

  • Cytomegalovirus Mononucleosis

    In patients with pharyngitis, palatal petechiae may also be a sign of a granulocytosis caused by aplastic anemia or a lymphoreticular malignancy involving the bone marrow[emedicine.medscape.com] This is the first report of transient pseudothrombocytopenia in CMV mononucleosis with mixed cryoglobulinemia.[ncbi.nlm.nih.gov] skin.[hopkinsmedicine.org]

  • Autoimmune Hepatitis

    We herein report a case of severe aplastic anemia diagnosed in an 8-year-old girl with a previous diagnosis of autoimmune hepatitis.[ncbi.nlm.nih.gov] cryoglobulinemia is more common.[merckmanuals.com] discoloration of the skin and the whites of the eyes ( jaundice ).[labtestsonline.org]

  • Liver Cirrhosis

    anemia, glomerulonephritis and vasculitis.[ncbi.nlm.nih.gov] Yellow discoloration in the skin and eyes (jaundice) Fluid accumulation in your abdomen (ascites) Spiderlike blood vessels on your skin Redness in the palms of the hands[mayoclinic.org] anemia and the fourth died in an accident.[ncbi.nlm.nih.gov]

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