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55 Possible Causes for Aplastic Anemia, Hemoglobin Decreased, Total Iron Binding Capacity Increased

  • Paroxysmal Nocturnal Hemoglobinuria

    The frequency of PNH clone detected in aplastic anemia and non-aplastic anemia groups was 12.02 and 3.36%, respectively.[ncbi.nlm.nih.gov] In conclusion, the results demonstrated the minor alleles of CR1 polymorphisms were lower in Chinese patients than in Caucasians, with a decrease in hemoglobin level.[ncbi.nlm.nih.gov] Together, these results argue that the decline in hemoglobin A1c was due to decreased RBC survival secondary to PNH.[ncbi.nlm.nih.gov]

  • Iron Deficiency Anemia

    anemia Myelodysplastic syndromes Severe combined immunodeficiency (SCIDS) Solid tumors, including Wilms tumor , rhabdomyosarcoma , neuroblastoma , osteosarcoma and Ewing[stlouischildrens.org] Although the risk of GI cancer (GIC) increases as hemoglobin decreases, guidelines do not usually recommend hemoglobin thresholds for IDA investigation.[ncbi.nlm.nih.gov] , with a corresponding decrease in total iron binding capacity.[ncbi.nlm.nih.gov]

  • Celiac Disease

    Both aplastic anemia and celiac disease have a similar underlying autoimmune process but an association between the two is seldom reported.[ncbi.nlm.nih.gov] Timely intervention of either celiac disease through strict gluten-free diet or aplastic anemia through immunosuppressive therapy could potentially reduce the risk for other[ncbi.nlm.nih.gov] This is the fourth case report suggesting an association between celiac disease and aplastic anemia in the pediatric population and this association could be more common than[ncbi.nlm.nih.gov]

  • Cooley's Anemia

    anemia;Fanconi anemia; Osteopetrosis;Selected cases of hemoglobinopath...[clinicaltrialsregister.eu] Cooley's anemia disease causes a dramatic decrease in the production of hemoglobin, resulting in anemia. This anemia can cause people to be more tired than normal.[dshs.state.tx.us] Rarely, aplastic anemia is due to an inherited (genetic) disorder such as Fanconi anemia.[labtestsonline.org]

  • Sideroblastic Anemia

    Although cases of classical "aplastic anemia" with hypocellular or fatty marrow comprise the bulk of this group, there remains a small but nonetheless puzzling number wherein[annals.org] Four weeks later, the hemoglobin level decreased to 7 g per deciliter, and sideroblasts reappeared in the bone marrow.[nejm.org] iron), total iron binding capacity (TIBC) normal or decreased (due to increased ferritin and iron).[stepwards.com]

  • Hereditary Spherocytosis

    […] punctuated by episodes of severe aplastic anemia (failure of bone marrow to produce cells).[britannica.com] All experienced an increase in hemoglobin and decrease in reticulocyte count early after LPS and at last follow-up. Twenty-two were sent for genetic analysis.[ncbi.nlm.nih.gov] Post-splenectomy blood changes include an increased hemoglobin level, decreased reticulocyte count, and the appearance of specific inclusion bodies and target cells.[steadyhealth.com]

  • Idiopathic Refractory Anemia

    Aplastic anemia (AA) needs to be differentiated from hypoplastic MDS particularly primary hypoplastic refractory anemia (PHRA) because of the impact on management and prognosis[ncbi.nlm.nih.gov] ) to 10.52 0.41 g per deciliter (6.5 0.25 mmol per liter), whereas hemoglobin concentrations in the placebo group decreased from 8.69 0.11 g per deciliter (5.4 0.068 mmol[nejm.org] Serum iron , percentage saturation and ferritin are increased. The total iron-binding capacity of the cells is normal to decreased.[en.wikipedia.org]

  • Hereditary Sideroblastic Anemia

    NOS Pyridoxine-responsive sideroblastic anemia NEC hereditary D64.0 hypochromic, sex-linked D64.0 ICD-10-CM Codes Adjacent To D64.0 D61.89 Other specified aplastic anemias[icd10data.com] Males affected with sideroblastic anemia had growth retardation, hypochromic microcytic anemia, elevated serum iron, decreased unsaturated iron-binding capacity, increased[ncbi.nlm.nih.gov] Serum iron , percentage saturation and ferritin are increased. The total iron-binding capacity of the cells is normal to decreased.[en.wikipedia.org]

  • Anemia of Chronic Disease

    Aplastic anemia : In people with aplastic anemia, the bone marrow does not produce enough blood cells, including red blood cells.[webmd.com] Decreased hemoglobin is often anemia of chronic disease and may be due to the effects of inflammatory cytokines on erythroid progenitor cells.[ncbi.nlm.nih.gov] The result is decreased total serum iron, but iron binding capacity is reduced as well, resulting in a somewhat decreased saturation, but increased ferritin.[library.med.utah.edu]

  • Anemia

    Aplastic anemia occurs if your bone marrow stops producing red blood cells.[hematology.org] It is defined by abnormally low hemoglobin concentration or decreased red blood cells. Several classification systems exist.[ncbi.nlm.nih.gov] Total iron-binding capacity (TIBC) and transferrin are measurements of iron transport proteins that increase in iron deficiency.[bloodjournal.org]

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