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37 Possible Causes for Aplastic Anemia, Hypersplenism, Leukocyte Alkaline Phosphatase Increased

  • Chronic Lymphocytic Leukemia

    Risk of aplastic anemia in patients using antiepileptic drugs. Epilepsia 47(7),1232–1236 ( 2006 ). Google Scholar 115 Chateauvieux S, Eifes S, Morceau F et al.[oadoi.org] The multiple possible causes of cytopenia in CLL (bone marrow failure, hypersplenism, chemotherapy, sepsis, autoimmunity) and the possibility of two or more causes occurring[haematologica.org] anemia, European Journal of Haematology, 76, 6, (502-509), (2006).[doi.org]

  • Aplastic Anemia

    Acquired cases of aplastic anemia are most common and in many cases they are temporary. Inherited cases of aplastic anemia are relatively uncommon.[symptoma.com] But the patient's splenomegaly was very mild (14 cm) and insufficient to cause symptoms of hypersplenism.[jscisociety.com] Aplastic anemia involves all different cell lines.[en.wikipedia.org]

  • Leukoerythroblastic Anemia

    Aplastic anemias I.[clinicaladvisor.com] leukocyte alkaline phosphatase: 100 score; increased vitmain B12 900 pg/mL or B12 binding protein 2200 pg/mL Treatment of polycythemia vera phlebotomy to reduce hyperviscosity[memorize.com] Available from: Sir, Leukoerythroblastic anemia is seen in patients with megaloblastic anemia, septicemia, acute hemolysis, hypersplenism, disseminated intravascular coagulation[ijpmonline.org]

  • Myeloproliferative Disease

    Abstract Long-term exposure to benzene has been associated with several blood malignancies, including aplastic anemia, myeloproliferative neoplasms, and different leukemias[ncbi.nlm.nih.gov] A myeloproliferative disorder manifested by thrombocytosis, a high leukocyte alkaline phosphatase (LAP) score and an increased red blood cell mass was found in a 64-yr-old[ncbi.nlm.nih.gov] As peripheral blood count abnormalities may sometimes be masked by hypersplenism, other secondary radiologic findings may be the only clue to an occult myeloproliferative[radiopaedia.org]

  • Myelodysplasia

    Who has aplastic anemia and MDS?[niddk.nih.gov] Familial cyclic neutropenia Antineutrophil antibody syndromes Isolated thrombocytopenia Idiopathic thrombocytopenic purpura Hypersplenism Dyserythropoiesis Ring sideroblasts[arupconsult.com] Aplastic Anemia and Myelodysplasia Association of Canada The Aplastic Anemia & Myelodysplasia Association of Canada (AAMAC) is a volunteer-run organization supporting patients[mds-alliance.org]

  • Agranulocytosis

    Analgesic use 29 to 180 days before admission was compared between 113 cases of aplastic anemia and 1724 controls.[jamanetwork.com] […] radiotherapy and immunosuppressants; Hematological and neoplastic diseases; Systemic diseases that are known to cause neutropenia or pancytopenia, such as lupus, HIV infection and hypersplenism[scielo.br] Other causes are viral, bacterial or parasitic infections; blood disorders; autoimmune neutropaenia; toxic agents; hypersplenism; cirrhosis; mitochondrial disease; cyclic[onlinelibrary.wiley.com]

  • Primary Myelofibrosis

    Aplastic anemia This is a condition where there is loss or suppression of production of RBCs.[news-medical.net] alkaline phosphatase (LAP) score is increased Treatment Reduced intensity allogeneic stem cell transplant if intermediate to high risk or palliation of extramedullary hematopoiesis[pathologyoutlines.com] Anaemia (may occur due to ineffective erythropoiesis, erythroid hypoplasia and hypersplenism) may cause fatigue, weakness and dyspnoea.[patient.info]

  • Idiopathic Neutropenia

    However, in immune-mediated bone marrow failure syndromes, such as acquired aplastic anemia and chronic idiopathic neutropenia, in which the pathophysiology results from a[ncbi.nlm.nih.gov] Measurement of the leukocyte alkaline phosphatase activity can be a useful screening test in cases of moderate neutrophilia (15 to 25 103 neutrophils/µl [15–25 109 neutrophils[medtextfree.wordpress.com] Hypersplenism Felty syndrome Immunophenotyping. Neutropenia, Splenomegaly and Rheumatoid arthritis.[rcpa.edu.au]

  • Liver Failure

    The fact that it is a successful therapeutic agent in some patients with aplastic anemia may be due to its proven ability to increase endogenous erythropoietin levels or to[ncbi.nlm.nih.gov] Big spleens and hypersplenism: fix it or forget it? Liver Int 2015;35:1492–8. Kedia S, Goyal R, Mangla V, Kumar A, S S, Das P, et al.[revistagastrocol.com] MANAGEMENT • HEMATOLOGIC : Aplastic anemia – Bone marrow failure, – characterized by a spectrum of features ranging from mild pancytopenia to aplastic anemia – occurs in a[slideshare.net]

  • Polycythemia Vera

    An anonymous 17-question survey was emailed to members of the Myeloproliferative Neoplasm (MPN) Research Foundation database and Aplastic Anemia and MDS International Foundation[ncbi.nlm.nih.gov] leukocyte alkaline phosphatase , increased vit.B12 level, decreased folic acid level, elevated alk.phosphatase & conjungated bilirubin, hypercalcemia.[enotes.tripod.com] (post-PV myelofibrosis ), in which cytopenia s, including anemia, are associated with ineffective hematopoiesis, bone marrow fibrosis, extramedullary hematopoiesis, and hypersplenism[seer.cancer.gov]

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