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331 Possible Causes for Aplastic Anemia, Lactate Dehydrogenase Increased

  • Infectious Mononucleosis

    Infectious mononucleosis (IM) is a rare cause of aplastic anemia in adults.[ncbi.nlm.nih.gov] anemia requiring bone marrow transplantation, are rare. 2 Neurologic complications occur in 1% to 5% of cases and can include Guillain-Barré syndrome, facial-nerve palsy,[uspharmacist.com] We report of a patient in whom aplastic anemia, mucormycosis and aspergillosis complicated during the course of IM and successfully treated with liposomal amphotericin B.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    The frequency of PNH clone detected in aplastic anemia and non-aplastic anemia groups was 12.02 and 3.36%, respectively.[ncbi.nlm.nih.gov] The effect of eculizumab on intravascular hemolysis was demonstrated by a reduction in lactate dehydrogenase levels at all measurements after baseline.[ncbi.nlm.nih.gov] After approximately 2 years, apart from normalization of the lactate dehydrogenase (LDH) level, there was an increase in glycosylphosphatidylinositol (GPI) negative red cells[nejm.org]

  • Leukemia

    Aplastic Anemia. Only neutropenia is regarded as independent risk factor for severe opportunistic infection in T-LGL patients.[ncbi.nlm.nih.gov] Aplastic anemia, viral infections such as infectious mononucleosis, and vitamin B 12 and folate deficiencies should be considered in the differential diagnosis of severe pancytopenia[merckmanuals.com] In contrast to aplastic anemia, leukemia results in a highly cellular marrow.[library.med.utah.edu]

  • Erythema Infectiosum

    However, the disease does not lead to a positive outcome in patients who are immunocompromised or already suffering from reticulocytopenia, hemolytic anemia or aplastic anemia[symptoma.com] […] crisis in pts w/hemolytic anemias Arthropathy, aplastic anemia us. resolve w/in 2-4wks (rarely may last yrs) Aplastic crisis rare once rash appears Chronic anemia in immunocompromised[fprmed.com] Wong S, Young NS, Brown KE: Prevalence of parvovirus B19 in liver tissue: no association with fulminant hepatitis or hepatitis-associated aplastic anemia.[springermedizin.de]

  • Systemic Lupus Erythematosus

    Other conditions Other conditions like thyroid disorders (particularly over active thyroid glands), aplastic anemia, rheumatoid arthritis, parasitic infestations, vitamin[news-medical.net] . – Adverse effects :Retinal damage, agranulocytosis, aplastic anemia, cardiomyopathy, myopathy, peripheral neuropathy, pigmentation of skin, Quinacrine : diffuse yellow skin[slideshare.net] […] immune system, such as HIV, which destroy T lymphocytes Hypersplenism This is caused by enlargement of spleen that destroys the blood cells leading to leukopenia as well as anemia[news-medical.net]

  • Acquired Immunodeficiency Syndrome

    anemia ( D61.9 ) pancytopenia (due to) (with) bone marrow infiltration ( D61.82 ) pancytopenia (due to) (with) congenital (pure) red cell aplasia ( D61.01 ) pancytopenia[icd10data.com] […] virus [HIV] disease ( B20 ) ICD-10-CM Diagnosis Code D61.81 Pancytopenia 2016 2017 2018 2019 Non-Billable/Non-Specific Code Type 1 Excludes pancytopenia (due to) (with) aplastic[icd10data.com]

  • Chronic Arsenic Poisoning

    Markers of inflammation (macrophage, lactate dehydrogenase, nitric oxide) were apparently more in the BAL fluid of those with lung involvement than in those without, though[ncbi.nlm.nih.gov] Worsening of these parameters correlated with increasing degree of arsenic toxicity.[ncbi.nlm.nih.gov]

  • Cutaneous T-Cell Lymphoma

    Although several reports indicate the relationship between EF and hematological disorders such as aplastic anemia, polycythemia vera, or myelomonocytic leukemia, the association[ncbi.nlm.nih.gov] No notable differences in rates of increased levels of serum lactate dehydrogenase (LDH) were observed (17 of 17 pEBVd( ) vs. 27 of 29 pEBVd(-)). pEBVd detection was associated[ncbi.nlm.nih.gov] Lactate dehydrogenase levels are often elevated.[symptoma.com]

  • Hemolytic Transfusion Reaction

    Anti-AnWj causing acute hemolytic transfusion reactions in a patient with aplastic anemia. Transfusion 2012;52:1476-81. 3.[ajts.org] Other examinations that prove hemolysis are the reduction of the plasma haptoglobin and hemopexin concentration, as well as an increase in the lactate dehydrogenase and bilirubin[symptoma.com] Laboratory assessment is based on a positive Direct Antiglobulin Test (DAT), a decrease in serum haptoglobin , and an increase in blood levels of the enzyme lactate dehydrogenase[en.wikipedia.org]

  • Graft Rejection

    Allogeneic BMT for severe aplastic anemia is associated with a significant rate of graft rejection, especially in patients who have been previously transfused.[ncbi.nlm.nih.gov] In addition, laboratory parameters including C-reactive protein (CRP), lactate dehydrogenase (LDH), fibrinogen, and D-dimer as possible differentiation markers for graft rejection[ncbi.nlm.nih.gov] We report a child with aplastic anemia who rejected donor marrow twice despite adequate immunosuppression as part of the conditioning therapy but engrafted successfully following[ncbi.nlm.nih.gov]

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