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545 Possible Causes for Areflexia, Thrombocytopenic Purpura

  • Thrombocytopenia

    Abstract Thrombotic thrombocytopenic purpura (TTP) is an acute, life-threatening illness with disseminated platelet-rich thromboses of small vessels that variably presents[ncbi.nlm.nih.gov] What is immune thrombocytopenic purpura? Immune thrombocytopenic purpura (ITP) is an autoimmune disorder.[patient.info] You may hear it called by its old name, idiopathic thrombocytopenic purpura.[webmd.com]

  • Primary CD59 Deficiency

    Immune thrombocytopenic purpura, which may lead to bleeding, is typically caused by antibodies directed against the platelet glycoprotein IIb/IIIa complex.[nejm.org] purpura, Erythroderma (congenital, with palmoplantar keratoderma), Hypotrichosis and Hyper IgE, Factor II deficiency, Factor V deficiency, Factor X deficiency, Factor XI[bbrauncegat.com] Defibrotide as a promising treatment for thrombotic thrombocytopenic purpura in patients undergoing bone marrow transplantation.[revistanefrologia.com]

  • Oculo-Pharyngo-Distal Myopathy

    Inclusion body myositis associated with celiac sprue and idiopathic thrombocytopenic purpura. South Med J . 2003 Jul. 96(7):721-3. [Medline] .[emedicine.staging.medscape.com] Difficulty Swallowing 433 Case 69 A Young Woman with Intermittent Weakness and a Positive Family History of Similar Problems 436 Case 70 A Woman with Muscle Weakness and Areflexia[books.google.com] Inclusion body myositis associated with celiac sprue and idiopathic thrombocytopenic purpura. South Med J. 2003 Jul. 96(7):721-3. [Medline].[emedicine.medscape.com]

  • Enterovirus Infection

    Interestingly enough, actually, in patients with chronic idiopathic thrombocytopenic purpura (ITP) and Helicobacter pylori infection eradication is suggested by the European[ncbi.nlm.nih.gov] Abstract Miller-Fisher is a rare syndrome of childhood that presents with external ophthalmoplegia, ataxia, and areflexia.[ncbi.nlm.nih.gov]

  • Bickerstaff Brainstem Encephalitis

    Jaso R, Sierra M, Calleja J, Valero C, Pascual J: Guillain-Barré syndrome after rituximab in a patient with idiopathic thrombocytopenic purpura: a causal association?[karger.com] He also suggested that MFS and BBE may belong to the same group of disorders as syndrome of ophthalmoplegia, ataxia and areflexia (SOAA).[ncbi.nlm.nih.gov] Google Scholar [2] Al-Din A.S.N. : The nosological position of the ophthalmoplegia, ataxia and areflexia syndrome: “The spectrum hypothesis” .[link.springer.com]

  • Déjerine-Sottas Disease

    purpura, familial 274150 A D A M TSL2 9q34.2 Geleophysic dysplasia 1 231050 AD C K 3 1q42.13 Coenzyme Q10 deficiency, primary, 4 612016 A FF2 (FMR2) Xq28 Mental retardation[institutobernabeu.com] There was a significantly greater incidence of ataxia, areflexia and clinical nerve enlargement in HMSN type III.[ncbi.nlm.nih.gov] […] disease is characterized by an early-onset (i.e. in childhood) demyelinating neuropathy, and usually manifests as gradual progression of distal weakness, sensory loss, and areflexia[radiopaedia.org]

  • Vitamin B12 Deficiency

    As a subset of microangiopathic hemolytic anemia, thrombotic thrombocytopenic purpura can present with a constellation of symptoms similar to the hemolytic anemia attributed[ncbi.nlm.nih.gov] This is followed by disturbances of proprioception, vibratory sense, and areflexia. Patients may mention clumsiness, poor coordination, and difficulty walking.[doi.org] Although thrombotic thrombocytopenic purpura (TTP) is rare, early diagnosis and treatment are important for decreasing the mortality rate.[ncbi.nlm.nih.gov]

  • Guillain-Barré Syndrome

    High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet. 1981; 1 :1228–1231. [ PubMed ] [ Google Scholar ] 30.[ncbi.nlm.nih.gov] Areflexia and sensory disturbances are also common. Patients with GBS usually have albuminocytological dissociation on cerebrospinal fluid (CSF) analysis.[ncbi.nlm.nih.gov] , 49 with anaphylaxis, 37 with angioedema, 30 with anaphylactic laryngeal edema, 11 with an Arthus reaction, 3 with atopic dermatitis, 3 with thrombocytopenic purpura, and[dx.doi.org]

  • Friedreich Ataxia

    purpura.[ncbi.nlm.nih.gov] Friedreich ataxia (FRDA) is an autosomal recessive, neurodegenerative disease, characterized by progressive gait and limb ataxia, dysarthria, lower-limb areflexia, Babinski[ncbi.nlm.nih.gov] This autosomal-recessive neurodegenerative disease is characterized by progressive gait and limb ataxia, dysarthria, lower-limb areflexia, decreased vibration sense, muscular[ncbi.nlm.nih.gov]

  • Polyneuropathy

    Concurrent association of idiopathic thrombocytopenic purpura (ITP) and peripheral neuropathy is a rare condition.[ncbi.nlm.nih.gov] It often presents with symptoms that include tingling or numbness (beginning in the toes and fingers), weakness of the arms and legs, loss of deep tendon reflexes (areflexia[ninds.nih.gov] Patients typically present with a gradual and protracted ( 2 month) weakness of both proximal and distal musculature associated with areflexia and sensory changes 3 .[radiopaedia.org]

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