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13 Possible Causes for Arterial Blood pH Increased, Hyperreninemia, Muscle Weakness

  • Bartter's Disease

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Saint-Petersburg, Russia Abstract Abstract Bartter syndrome (BS) tubulopathy with autosomal recessive (AR) type of genetic inheritance, manifested hypokalemia, metabolic alkalosis, hyperreninemia[adc.bmj.com] Low blood levels of potassium can cause muscle weakness, cramping, and fatigue.[webmd.com]

  • Conn Syndrome

    Hence, arterial pH will increase slightly, resulting in an inhibitory response of the respiratory centre in the brain.[academic.oup.com] Low potassium may cause fatigue, muscle cramps, muscle weakness, numbness, or temporary paralysis.[endocrinediseases.org] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au]

  • Hypokalemia

    Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides.[ncbi.nlm.nih.gov] Clinical features include transient periods of muscle weakness and tetany, dizziness, abdominal pains and constipation.[ncbi.nlm.nih.gov] Proximal muscle weakness is observed most commonly in lower extremities; cranial muscles are normal, but constipation and distention are prominent.[dovepress.com]

  • Metabolic Alkalosis

    In most patients, the symptom of muscle weakness and polyuria occur early in life, which may be attributed to potassium depletion.[ncbi.nlm.nih.gov] Patients with ACET treatment significantly decreased their serum bicarbonate (p 0.01 versus baseline) and arterial blood pH (p 0.0001), increased their PaO(2)/FiO(2) ratio[ncbi.nlm.nih.gov] weakness; myalgia; muscle cramps; tremors in the hands; and twitching muscles.[battlediabetes.com]

  • Liddle Syndrome

    Muscle weakness in combination with severe hypertension has been reported in elderly population with the syndrome [2].[ohsu.pure.elsevier.com] Hyperactive renin-angiotensin system (plasma renin increased, lack of effect of angiotensin on blood pressure, renal potassium wasting, increased renal prostaglandin production[patient.info] Muscle weakness this can be in the form of abdominal muscle weakness associated with constipation, weakness if chest muscles leading to dyspnea.[tandurust.com]

  • Respiratory Alkalosis

    […] reduces the arterial levels of carbon dioxide that, in turn, elevates the blood pH beyond the normal range (7.35-7.45) Statements Identifiers Sitelinks Wikipedia (13 entries[wikidata.org] weakness, depressed central respiratory drive, and resultant alveolar hypoventilation.[ncbi.nlm.nih.gov] , Cl- expansion Renal loss of H : edematous states (heart failure, cirrhosis, nephrotic syndrome), hyperaldosteronism, hypercortisolism, excess ACTH, exogenous steroids, hyperreninemia[thoracic.org]

  • Alkalosis

    Clinical features include transient periods of muscle weakness and tetany, abdominal pains, and chondrocalcinosis. [ 8 ] Other features include: Short stature.[patient.info] Increases in arterial blood pH depress respiratory centers. The resulting alveolar hypoventilation tends to elevate PaCO2 and restore arterial pH toward normal.[openanesthesia.org] weakness; myalgia; muscle cramps; tremors in the hands; and twitching muscles.[battlediabetes.com]

  • Malignant Hypertension

    Effects - Respiratory and airway - muscle weakness causing dysarthria in the awake, non intubated patient.[anaesthetist.com] Initial evaluation demonstrated hyperreninemia with hyperaldosteronism and a possible renal artery stenosis at the contrast-enhanced CT scan.[ncbi.nlm.nih.gov] These analyses showed that our patient had a hyperreninemia with a secondary hyperaldosteronism (renin 266.4 microUI/mL, aldosterone 38.1 ng/dL), which could be due to the[ncbi.nlm.nih.gov]

  • Renal Tubular Acidosis

    A 33-year-old HIV-positive man with Hepatitis C and tuberculous lymphadenitis was admitted due to deep venous thrombosis and generalized muscle weakness.[ncbi.nlm.nih.gov] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[jpma.org.pk] HCO 3 - increased by 1 mmol/L in a mean of 12   2 min with IHD versus 34   8 min withr CRRT (P  0.001), while arterial blood pH increased 0.01 in a mean of 7   1 mins with[emedicine.medscape.com]

  • Respiratory Acidosis

    Measurement of transdiaphragmatic pressure is a useful diagnostic test for documenting respiratory muscle weakness.[emedicine.com] , Cl- expansion Renal loss of H : edematous states (heart failure, cirrhosis, nephrotic syndrome), hyperaldosteronism, hypercortisolism, excess ACTH, exogenous steroids, hyperreninemia[thoracic.org] Key diagnostic test is arterial blood gasses. Increased ventilation with increased inspired oxygen should improve CO2, PO2, and pH.[clinicaladvisor.com]

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