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95 Possible Causes for Arthralgia, Bone Spicules, Knee Pain

  • Malignant Bone Neoplasm

    Sunburst and hair-on-end periosteal formations also are associated with aggressive bone tumors and are radiating spicules of periosteal bone.[podiatrytoday.com] Chondroblastoma Rare, normally in epiphysis of long bones - eg, the hip, shoulder and knee.[patient.info] It may be spiculated and interrupted - sometimes there is a Codman's triangle.[radiologyassistant.nl]

  • Acute Polyarticular Gouty Arthritis

    Additionally, because of the chronicity of the process, bone production leads to sclerotic borders, overhanging edges, bony enlargement, and irregular spicules at the sites[rheumtutor.com] Joints may simply be painful (arthralgia) or also inflamed (arthritis).[merckmanuals.com] Three days into his admission he begins to complain of severe bilateral wrist, elbow, and right knee pain. On exam, he is febrile to 38.22  C (100.8  F).[basicmedicalkey.com]

  • Muckle-Wells Syndrome

    The borders of the ossified portions of the epiphyses are spiculated and uneven. Eventually, long bones develop bowing of the ends and shortening of the diaphysis.[emedicine.medscape.com] Abstract The term Muckle-Wells syndrome (MWS) describes an autosomal dominant disorder characterised by various combinations of urticaria, sensorineural deafness, amyloidosis, arthralgia[ncbi.nlm.nih.gov] Even my husband wasn't understanding our sons battle with itching and knee pain. I was told Kids just get these things and since it goes away don't worry.[rareconnect.org]

  • Multiple Myeloma

    This fluid is predominantly blood, but mixed in are bone marrow particles (spicules) which are then spread onto glass slides, stained, and examined by hematologists and pathologists[cancer.ucsf.edu] The most common symptoms are joint pain (arthralgia), pain and numbness in the fingers and toes in response to cold (Raynaud’s phenomenon), weakness, and purpura.[rarediseases.org] CASE REPORT A 56-year-old man with multiple myeloma presented with chronic polyarticular pain and swelling.[ncbi.nlm.nih.gov]

  • Osteomyelitis

    […] detached necrotic cortical bone (develops after 30 days) Cloaca formation space in which dead bone resides MR findings Bone marrow hypointense on T1WI hyperintense on T2WI[learningradiology.com] Ages range from 39 to 64 years, and reasons for amputation included infection, pain, and necrosis.[ncbi.nlm.nih.gov] The essentials of the diagnosis include an initial presentation with pain at a knee or hip joint and tenderness over the vertebral bodies.[journals.lww.com]

  • Erdheim-Chester Disease

    Resnick has described a pattern of bony proliferation that is pathognomonic for POEMS syndrome: irregular and spiculated bone contours at areas of tendinous and ligamentous[roentgenrayreader.blogspot.com] Common side effects include injection site reactions, headache, arthralgias, and nasopharyngitis.[doi.org] We present a 40 years old woman who for the last two years had various systemic symptoms, especially knee pain, polyuria and polydipsia.[ncbi.nlm.nih.gov]

  • Paraneoplastic Syndrome

    In contrast to RP, intraretinal bone spicule migration is rare with either AZOOR or paraneoplastic retinopathies.[reviewofophthalmology.com] Sweet’s Syndrome  Acute febrile neutrophilic dermatosis  Associated with leukemia  Acute tender red nodules or plaques  Fever, arthralgia, oral lesions, eye involvement[slideshare.net] Hypertrophic osteoarthropathy is prominent with certain lung cancers and manifests as painful swelling of the joints (knees, ankles, wrists, elbows, metacarpophalangeal joints[merckmanuals.com]

  • Familial Cold Autoinflammatory Syndrome Type 1

    The borders of the ossified portions of the epiphyses are spiculated and uneven. Eventually, long bones develop bowing of the ends and shortening of the diaphysis.[emedicine.medscape.com] Abstract Familial cold urticaria (FCU) is a rare autosomal dominant inflammatory disorder characterized by intermittent episodes of rash with fever, arthralgias, conjunctivitis[ncbi.nlm.nih.gov] In addition to the rash, episodes are characterized by fever, chills and joint pain, most often it affects the hands, knees and ankles.[ivami.com]

  • Syphilis

    ., spiculated or thickened) does not allow the treponematoses to be distinguished.[cid.oxfordjournals.org] Systemic manifestations include malaise, fever, myalgias, arthralgias, lymphadenopathy, and rash.[emedicine.com] In his book In the Land of Pain , translated and edited by Julian Barnes in 2002, the writer's eye is unflinching as he faces "the torment of the Cross: violent wrenching[theguardian.com]

  • Fibrous Dysplasia

    Fibrous dysplasia is a developmental disorder of bone in which lesions develop fibrous tissue and spicules of woven bone [17].[doi.org] CASE PRESENTATION: A 14-year-old Asian girl was referred to our hospital after slipping down with pain on the left knee.[ncbi.nlm.nih.gov] […] along his knee.[orthobullets.com]

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