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86 Possible Causes for Arthralgia, C-Reactive Protein Increased, Progressive Contractures

  • Polyarthritis

    Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and leukocytes were increased.[ncbi.nlm.nih.gov] The characteristic rapid progression of palmar contracture is a key finding that suggests the potential existence of a malignancy. [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov] Although bisphosphonates are safety drugs, they have numerous side-effects such as arthralgia, elevated erythrocyte sedimentation rate and C-reactive protein, gastrointestinal[ncbi.nlm.nih.gov]

  • Osteoarthritis

    Increased serum C-reactive protein levels by immunonephelometry in patients with rapidly destructive hip osteoarthritis. Rev Rhum Engl Ed. 1998;65:759–765.[doi.org] Another characteristic symptom of the disease is the progressive incapacity of the joint to function, leading – in the long run – to loss of mobility.[oafifoundation.com] (Redirected from Joint pain ) Arthralgia (from Greek arthro-, joint -algos, pain) literally means joint pain. [1] [2] Specifically, arthralgia is a symptom of injury, infection[en.wikipedia.org]

  • Cryopyrin-Associated Periodic Syndrome

    Acute phase reactants in blood, such as erythrocyte sedimentation rate ( ESR ), C-reactive protein ( CRP ) and serum amyloid A (SAA), are markedly increased, even when the[dermnetnz.org] In contrast to other NOMID manifestations, bone lesions continue to progress despite adequate IL-1 blockade.[rheumatologyadvisor.com] […] syndrome caused by mutations of the CIAS1 gene (currently named NLRP3), and is characterized by periodic attacks of an urticaria-like rash, fever, head-ache, conjunctivitis and arthralgia[ncbi.nlm.nih.gov]

  • CINCA Syndrome

    […] in the number of white blood cells Elevation in levels of the protein amyloid A and C-reactive protein in the blood and an increase in the erythrocyte sedimentation rate[patientworthy.com] It can lead to progressive contracture of the knees and elbows with joint deformity due to patella or epiphysis overgrowth.[healio.com] In terms of joint involvement, recurrent flares that may be accompanied with overgrowth of the patella are most frequently reported, together with arthralgia that can be severe[symptoma.com]

  • Arthritis

    BMI, triglycerides, and C-reactive protein.[medicalnewstoday.com] Flexion contractures may require intensive exercise, casting, or immobilization (eg, splinting) in progressively more stretched-open positions.[merckmanuals.com] The characteristics present are chronic synovitis, arthralgia, impaired joint mobility in at least one joint, and erosion with destruction of cartilage and subchondral bone[ncbi.nlm.nih.gov]

  • Osteoarthritis of the Knee

    In knee osteoarthritis, high-sensitivity C-reactive protein concentration may increase in early-stage KL-II. The Author(s) 2015.[ncbi.nlm.nih.gov] , knee ROM, medial BMLs, medial subchondral bone cysts and medial trabecular bone texture are associated with the cOA progression.[arthritis-research.biomedcentral.com] RESULTS: The cell-based product was well tolerated with few reported Adverse Events (mild arthralgia and low back pain).[ncbi.nlm.nih.gov]

  • Calcium Pyrophosphate Arthropathy

    Occasionally, a gout attack triggers a systemic inflammatory response manifesting with fevers, leukocytosis, elevated sedimentation rates, and elevated C-reactive protein[clevelandclinicmeded.com] Signs: Pseudo-Rheumatoid (5% of CPPD Deposition Disease) Symmetric Polyarthritis with low grade inflammation Synovial thickening Flexion contractures Morning Stiffness Fatigue[fpnotebook.com] In addition, induction of transient arthralgias in some patients is a well-recognized adverse effect of MTX [ 18 ], which could have further obscured a potential beneficial[arthritis-research.biomedcentral.com]

  • Erythema Nodosum

    The ESR is typically high, the C-reactive protein elevated, and the blood showing an increase in white blood cells.The ESR is initially very high, and falls as the nodules[en.wikipedia.org] Subsequently the patient developed progressive skin and joints contracture. A repeated skin biopsy done three months later confirmed the diagnosis of NSF.[ncbi.nlm.nih.gov] In this case report, we suggest arthralgia, EN, and Achilles tendinitis could coexist with AGPB.[ncbi.nlm.nih.gov]

  • Pseudogout

    Blood investigations included a normal full blood count (haemoglobin 144 g/l, platelets 229 10 9 /l, white cell count 10.5 10 9 /l), C reactive protein 33 mg/l (normal 0–6[ard.bmj.com] Signs: Pseudo-Rheumatoid (5% of CPPD Deposition Disease) Symmetric Polyarthritis with low grade inflammation Synovial thickening Flexion contractures Morning Stiffness Fatigue[fpnotebook.com] In this case, a 56-year-old caucasian male presented with right sided preauricular swelling, temporomandibular joint arthralgia and restricted mouth opening; he developed[ncbi.nlm.nih.gov]

  • Nakajo Syndrome

    Laboratory findings include constantly elevated C-reactive protein (CRP) levels and hyper-gamma-globulinemia.[orpha.net] Patients with CANDLE can also have conjunctivitis, arthralgia without arthritis, nodular episcleritis (irritation and inflammation on the tissue covering the white part of[autoinflammatory.org] Arthralgia without arthritis is also noted in most patients and significant joint contractures develop over time.[printo.it]

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