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15 Possible Causes for Arthralgia, Cardiac Arrhythmia, Severe Recurrent Orthostatic Hypotension

  • Amyloidosis

    Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org] […] with AL amyloidosis, but AA amyloidosis has also been reported. 39 Hepato/splenomegaly in patients with Schnitzler syndrome (IgM monoclonal gammopathy, urticarial rash, arthralgia[bloodjournal.org] Cardiac amyloidosis often goes undiagnosed, especially in its earliest stages, when symptoms—including shortness of breath, swelling in the legs, or cardiac arrhythmias, such[nyulangone.org]

  • Primary Amyloidosis

    Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org] […] para-protein (IgM-κ is most common) at the dermoepidermal junction and in capillary walls which probably contributes to development of chronic urticaria, intermittent fever, arthralgia[doi.org] […] the susceptibility of the cardiac conduction system to arrhythmia.[anesthesiology.pubs.asahq.org]

  • Acute Pandysautonomia

    Patient 6 had a history of recurrent ileus and severe abdominal pain.[journals.plos.org] Additional features of the cryoglobulinemic syndrome include purpura, skin ulcers, arthralgias, sicca syndrome, Raynaud’s phenomenon, glomerulonephritis, and lymphadenopathy[mjhid.org] These symptoms are often milder and may include sicca manifestations, postural orthostatism, cardiac arrhythmias, bladder dysfunction, or gastrointestinal dysmotility" Postural[followmeindenmark.blogspot.com]

  • Systemic Amyloidosis

    recurrent inflammation. 57 Supportive treatment of specific symptoms Although symptoms of dysautonomia are rare in AA amyloidosis, severe orthostatic hypotension may lead[ncbi.nlm.nih.gov] […] para-protein (IgM-κ is most common) at the dermoepidermal junction and in capillary walls which probably contributes to development of chronic urticaria, intermittent fever, arthralgia[doi.org] AL amyloidosis patients with dominant cardiac amyloid, who are without symptomatic pleural effusions and have no history of cardiac syncope or symptomatic arrhythmias, may[link.springer.com]

  • Dysautonomia

    Severe autonomic dysfunctions occur: alacrymia (loss of tear secretion), dysphagia, hypothermia, orthostatic hypotension, loss of fungiform papillas on tongue.[tankonyvtar.hu] […] rapid heartbeat (tachycardia), excessive sweating (hyperhidrosis), perspiration depletion (anhidrosis), nerve pain or numbness (paresthesia or neuropathy), and joint pain (arthralgia[clinicalposters.com] PURPOSE: Individuals with eating disorder (ED) are at an increased risk of cardiac arrhythmias due to cardiac dysautonomia, which may be exacerbated if depression is also[ncbi.nlm.nih.gov]

  • Capillary Leak Syndrome

    . - A man aged 61 had recurrent attacks of severe shock.[ntvg.nl] The most common side effects of IL-11 are arthralgias and myalgias, fatigue, nausea, and headache.[cancerjournal.net] arrhythmia (24%), compartment syndrome (20%), and acquired infections (19%).The prevention of episodes of SCLS has involved two approaches.[en.wikipedia.org]

  • Pure Autonomic Failure

    First, patients with PAF did not have severe urinary disturbances, which would lessen the risk of recurrent urinary infections, and they also did not have life threatening[jnnp.bmj.com] […] foreign body in the eye, increased lacrimation (tear production), blepharitis (inflammation of the eyelids), dry eye, ocular hyperaemia (red eye), eye pruritis (itching), arthralgia[sv.glosbe.com] In addition, patients with bradycardia or cardiac arrhythmias should be monitored carefully when receiving this agent as atrioventricular block and cardiac arrest have been[healio.com]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    Severe autonomic dysfunctions occur: alacrymia (loss of tear secretion), dysphagia, hypothermia, orthostatic hypotension, loss of fungiform papillas on tongue.[tankonyvtar.hu] […] for 3/12 in four or more joints Minor criteria Current/historic Brighton score of 1, 2 or 3/9 (0, 1, 2, 3/9 if 50 years old) Arthralgia for minimum of 3 months in 1–3 joints[medical-dictionary.thefreedictionary.com] arrhythmias [ 37 ].[ojrd.biomedcentral.com]

  • Familial Dysautonomia

    The latter leads to severe hypotension and may later trigger syncopes due to orthostatic hypotension.[symptoma.com] […] for 3/12 in four or more joints Minor criteria Current/historic Brighton score of 1, 2 or 3/9 (0, 1, 2, 3/9 if 50 years old) Arthralgia for minimum of 3 months in 1–3 joints[medical-dictionary.thefreedictionary.com] arrhythmias Sleep apnea Restrictive lung disease Average lifespan: Currently, the mean age of the FD population is approximately 15 years.[familialdysautonomia.org]

  • Optic Nerve Edema-Splenomegaly Syndrome

    Complications such as severe orthostatic hypotension, recurrent infections or venous thromboses should be evaluated on the basis of resultant impairment. C.[secure.ssa.gov] Ankle arthralgias are common.[autoinflammatory-search.org] Cardiac Cardiac arrhythmia and sudden death. Cardiac failure. Ocular Uveitis and conjunctivitis. Severe sight impairment (rare). Ocular sicca syndrome.[patient.info]

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