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10 Possible Causes for Arthralgia, Cold-Induced Muscle Cramps, Fatigue

  • Ehlers-Danlos Syndrome Classic-Like Type 1

    Other common features include foot and hand deformities (piezogenic papules, pes planus, broad forefeet, brachydactyly, and acrogenic skin of hands), severe fatigue and neuromuscular[orpha.net] Cases have been reported of patient manifesting chronic widespread pain, chronic headache occurring during pregnancy, depression and/or cold-induced muscle cramps, who have[bredagenetics.com] The mothers mostly had hypermobility, both affected fathers had chronic joint or back pain, but only 1 parent had chronic arthralgia in 4 or more joints.[academic.oup.com]

  • Myoadenylate Deaminase Deficiency

    The individuals with MDD fatigued after performing only 28% as much work as their non-MDD counterparts.[doi.org] […] dysfunction with exercise intolerance, cramps and acute painful rhabdomyolysis or myoglobinuria (with or without myalgia) induced by fever, fasting or prolonged exercise,[neuroweb.us] […] associated with overlap syndromes such as PM/SSc (most common), SLE/PM and other autoimmune disorders such as PM, SS, SSc, SLE, UCTD, MCTD, RA; common clinical features include arthralgias[sites.google.com]

  • Genetic Recurrent Myoglobinuria

    Some patients may complain about arthralgia (joint pain) and sensation of swollen joints, although joints will be found normal on clinical examination.[bredagenetics.com] With increasing duration of exercise, glycogen stores are depleted, and muscle fatigue emerges.[the-rheumatologist.org] On the other hand, those with carnitine palmityl transferase deficiency (CPT deficiency) may experience fatigue only after prolonged exercise.[mda.org]

  • Late-Onset Carnitine Palmitoyl Transferase II Deficiency

    Muscle pain and fatigue are frequent complaints.[flipper.diff.org] Cases have been reported of patient manifesting chronic widespread pain, chronic headache occurring during pregnancy, depression and/or cold-induced muscle cramps, who have[bredagenetics.com] The efficacy of prophylaetic shakuyaku-kanzo-to for myalgia and arthralgia following carboplatin and paclitaxel combination chemotherapy for non-small cell lung cancer.[jsom.or.jp]

  • Myoglobinuria

    The correlation between myoglobinuria and muscle power change suggests that muscle fatigue is associated with muscle breakdown.[ncbi.nlm.nih.gov] […] dysfunction with exercise intolerance, cramps and acute painful rhabdomyolysis or myoglobinuria (with or without myalgia) induced by fever, fasting or prolonged exercise,[neuroweb.us] […] nephropathy (consider renal biopsy) Sinus issues : granulomatosis with polyangiitis (“Wegener’s granulomatosis”) Lung issues : Goodpasture syndrome Child with: abdominal pain, arthralgias[medicalmediareview.com]

  • Severe Infantile Carnitine Palmitoyl Transferase II Deficiency

    Age-related fatigue.[webmd.com] Cases have been reported of patient manifesting chronic widespread pain, chronic headache occurring during pregnancy, depression and/or cold-induced muscle cramps, who have[bredagenetics.com] The clinical picture is characterized by recurrent attacks of rhabdomyolysis, muscular pains and fatigue, secondary to a prolonged physical exercise and sometimes aggravated[ncbi.nlm.nih.gov]

  • Autosomal Dominant Myoglobinuria

    […] hypomagnesemia; isolated renal magnesium wasting; renal hypomagnesemia type 2 Related symptoms: Autosomal dominant inheritance Seizures Hypertension Renal insufficiency Fatigue[mendelian.co] […] dysfunction with exercise intolerance, cramps and acute painful rhabdomyolysis or myoglobinuria (with or without myalgia) induced by fever, fasting or prolonged exercise,[neuroweb.us] […] nephropathy (consider renal biopsy) Sinus issues : granulomatosis with polyangiitis (“Wegener’s granulomatosis”) Lung issues : Goodpasture syndrome Child with: abdominal pain, arthralgias[medicalmediareview.com]

  • Hoyeraal-Hreidarsson Syndrome

    […] deletion syndrome Chromosome Xp11.3 Deletion Syndrome Chromosome Xq Duplication Syndrome Chromosome Xq28 Duplication Syndrome chronic atrial and intestinal dysrhythmia chronic fatigue[rgd.mcw.edu] muscle cramps Acute demyelinating polyneuropathy Spontaneous pain sensation Shoulder pain Abnormal nervous system electrophysiology Myelin outfoldings Onion bulb formation[mendelian.co] Toxicities associated with this treatment included mucocutaneous symptoms, abnormalities in liver function tests and triglyceride levels, and musculoskeletal symptoms such as arthralgias[renaldo.hassanflores.com]

  • Blindness - Scoliosis - Arachnodactyly Syndrome

    Orthotics should be worn by patients with JHS who have pes planus to improve posture and decrease fatigue of lower extremity muscles.[rheumatologyadvisor.com] muscle cramps Need help with a diagnosis?[mendelian.co] However, in other cases, mitral valve prolapse can result in chest pain, abnormal heart rhythms (arrhythmias), fatigue, and dizziness.[rarediseases.org]

  • Cataract - Ataxia - Deafness

    Some systemic associations may include life-threatening aortitis (up to 10%), inflammatory bowel disease, pericarditis, abdominal pain, fatigue, weight loss, arthralgia, myalgia[webeye.ophth.uiowa.edu] […] dysfunction with exercise intolerance, cramps and acute painful rhabdomyolysis or myoglobinuria (with or without myalgia) induced by fever, fasting or prolonged exercise,[neuroweb.us] Some systemic associations may include life-threatening aortitis (up to 10%), inflammatory bowel disease, pericarditis, abdominal pain, fatigue, weight loss, arthralgia, myalgia[webeye.ophth.uiowa.edu]

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