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53 Possible Causes for Arthralgia, Cryoglobulinemia, Yellow Discoloration of the Skin

  • Viral Hepatitis

    HCV RNA can be demonstrated in the tumor as well as in surrounding liver tissue although HCV RNA cannot be integrated in the hepatocytic DNA. 3--Essential cryoglobulinemia[meddean.luc.edu] The most notable symptom of acute viral hepatitis is jaundice, which is a yellow discoloration of the skin and the whites of the eyes.[patients.gi.org] […] followed by the prodromal period, which is characterized by acute manifestations such as fatigue, malaise, fever, anorexia, nausea, emesis, abdominal pain, urticaria, and arthralgia[symptoma.com]

  • Chronic Hepatitis C

    Approximately 80% of patients with hepatitis C virus infection develop chronic liver disease as cirrhosis, and 40% develop autoimmune complications as mixed cryoglobulinemia[ncbi.nlm.nih.gov] But over time, they can experience the following: tiredness weight loss nausea abdominal pain severe itching jaundice (yellow discoloration of the skin and eyes) Eventually[hepc.liverfoundation.org] Symptomatic patients may experience fatigue, nausea, anorexia, myalgia (muscle pain), arthralgia, weakness, and weight loss.[britannica.com]

  • Hepatitis B

    RESULTS: Clinical history, examinations, and laboratory results suggest HBV-associated cryoglobulinemia and vasculitis.[ncbi.nlm.nih.gov] Jaundice (a yellow discoloration of eyes and skin), which is usually a sign of liver damage, may not occur.[web.archive.org] Numerous extrahepatic manifestations have been reported in patients with both acute and chronic hepatitis B (arthralgias or arthritis, skin rashes, glomerulonephritis and[ncbi.nlm.nih.gov]

  • Syphilis

    Systemic manifestations include malaise, fever, myalgias, arthralgias, lymphadenopathy, and rash.[emedicine.com]

  • Autoimmune Disease

    Autoimmune diseases are the most frequently associated disorders and include rheumatoid arthritis, systemic lupus erythematosus, cryoglobulinemia, pemphigus vulgaris, and[ncbi.nlm.nih.gov] In severe cases the individual can develop a yellow discoloration to the skin and eyes known as jaundice.[primaryimmune.org] Most developed fever and arthralgias/arthritis. Other findings included serositis manifested by tachycardia, dyspnea and pleural effusions, headaches, and hair loss.[ncbi.nlm.nih.gov]

  • Hepatitis C

    Monoclonal IgM rheumatoid factor secreted by CD5-negative B cells during mixed cryoglobulinemia.[doi.org] Signs and symptoms include: Bleeding easily Bruising easily Fatigue Poor appetite Yellow discoloration of the skin and eyes (jaundice) Dark-colored urine Itchy skin Fluid[mayoclinic.org] Here, we report the case of a 62-year-old HCV GT-4 positive woman complaining of a headache, nausea, and arthralgia.[ncbi.nlm.nih.gov]

  • Hepatitis

    […] mellitus, which occurs three times more frequently in HCV-infected persons; glomerulonephritis, a type of kidney disease caused by inflammation of the kidney; essential mixed cryoglobulinemia[gi.org] A hepatitis infection is also associated with jaundice, a yellow discoloration of the skin and a yellowish color to the whites of the eyes.[healthychildren.org] ., fatigue, arthralgia, jaundice) in approximately one third of patients; however, the majority of patients are asymptomatic.[bestpractice.bmj.com]

  • Autoimmune Hepatitis

    cryoglobulinemia is more common.[merckmanuals.com] discoloration of the skin and the whites of the eyes ( jaundice ).[labtestsonline.org] At the time of diagnosis of AIH, patients presented with arthralgia, abdominal complaints, cutaneous involvement and fatigue as common symptoms.[ncbi.nlm.nih.gov]

  • Erythema Elevatum Diutinum

    […] the buttocks may also be involved. [2] Antecedent bacterial infections, collagen vascular diseases, myeloproliferative diseases, human immunodeficiency virus infection, cryoglobulinemia[idoj.in] Erythema elevatum diutinum (EED) is a rare type of skin disorder characterized as raised papules or plaques with a skin discoloration of red, purple, brown or yellow.[patientslikeme.com] A young woman with recurrent painful lesions on the dorsal aspects of her hands associated with arthralgia presented with pain and redness of both eyes.[ncbi.nlm.nih.gov]

  • Psoriasis

    In adults, Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, systemic lupus erythematosus, and mixed cryoglobulinemia (see these terms) should also[orpha.net] discoloration of the nails known as the oil drop or salmon spot, dryness, thickening of the skin under the nail (subungual hyperkeratosis), loosening and separation of the[en.wikipedia.org] […] case, the skin tightening was successfully improved and ustekinumab was more effective, even though oral prednisolone (9-12 mg/day) had some effect on skin tightening and arthralgia[ncbi.nlm.nih.gov]

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