Create issue ticket

23 Possible Causes for Arthralgia, Degeneration of Epidermal Basal Cells, Eosinophilia

  • Systemic Lupus Erythematosus

    In rare cases, pleural eosinophilia is associated with connective tissue disease.[ncbi.nlm.nih.gov] Here we report a case in which an elderly female presented with malar rash, intermittent fever, and arthralgia.[ncbi.nlm.nih.gov] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Erythema Multiforme

    […] cytopenia, vasculitis, acute allergic interstitial nephritis, occupational contact dermatitis, photoallergic dermatitis, maculopapular eruption, erythroderma, Drug rash with eosinophilia[aaaai.org] Systemic side effects of PCV13 include chills, fever, headache, vomiting, fatigue, arthralgia, myalgias, decreased appetite, and diarrhea, whereas its cutaneous adverse reactions[ncbi.nlm.nih.gov] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com]

  • Vasculitis

    All serologic studies were normal except for increased levels of rheumatoid factor and eosinophilia.[ncbi.nlm.nih.gov] Abstract IgA vasculitis (IgAV) commonly occurs in young children, who present with a tetrad of purpura, abdominal pain, arthralgia and nephritis.[ncbi.nlm.nih.gov] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org]

  • Lupus Erythematosus

    Other diagnoses included in these codes but without sufficient sample sizes to analyze individually are Felty’s syndrome, eosinophilia myalgia syndrome, juvenile chronic polyarthritis[doi.org] MUSCULOSKELETAL SYSTEM Musculoskeletal involvement is present in 95% of patients with SLE and manifests as arthralgias, myalgias, or nonerosive inflammatory arthritis. 10[aafp.org] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br]

  • Pityriasis Circinata

    In the drug induced form there is no herald patch, individual lesions tend to be violet-red in colour, pruritus is more severe, and eosinophilia may be present.[doi.org] A prodrome of malaise, headache, and sometimes arthralgia precedes the lesions in a minority of patients.[merckmanuals.com] Besides, histology shows epidermal atrophy and basal layer degeneration.[ncbi.nlm.nih.gov]

  • Erythema Marginatum

    Another patient experienced exacerbations of EAC premenstrually as a type of autoimmune progesterone dermatitis. [27] Hypereosinophilic syndrome: A patient with 31% eosinophilia[emedicine.medscape.com] Anti-inflammatory medications including salicylates and nonsteroidal agents are effective for the arthritis, fever, and arthralgia.[dermaamin.com] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in]

  • Chilblain Lupus Erythematosus

    Blood tests: FBC may show raised white count/eosinophilia or lymphopenia. Anaemia may be seen. ESR is often raised ( 65% of cases).[patient.info] Apart from arthralgias, there is no evidence for internal-organ disease or an increased susceptibility to infection.[edoc.mdc-berlin.de] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com]

  • Erythema Annulare Centrifugum

    There was no associated fever, lethargy, headache or arthralgia. He had a 15-year history of diabetes. He also had a 2-year history of hypertension.[academic.oup.com] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in] A 65-year-old male presented with a history of disseminated erythema annulare centrifugum lesions and a high peripheral blood eosinophilia (55%).[ncbi.nlm.nih.gov]

  • Graft-versus-Host-Disease

    But other patients with chronic GVHD never have eosinophilia, so the lack of eosinophilia does not influence the diagnosis of chronic GVHD.[cancertherapyadvisor.com] […] cough that is usually nonresponsive to bronchodilator therapy Neuromuscular – Generalized or focal weakness, neuropathic pain, vision loss, muscle cramps, myalgia Joints – Arthralgia[emedicine.com] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[ncbi.nlm.nih.gov]

  • Photosensitivity Disorder

    The syndrome typically includes skin rash and fever, often with hepatitis, arthralgias, lymphadenopathy, or haematological disorders (mainly eosinophilia and atypical lymphocytosis[pmj.bmj.com] People with lupus can also experience pain in the joints without swelling or tenderness, which is referred to as arthralgia.[lupusresearch.org] Microscopic evaluation revealed epidermal erosion and ulceration, with severe epidermal basal cell degeneration and necrosis, and superficial dermatitis (python and skink)[ncbi.nlm.nih.gov]

Similar symptoms