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5,247 Possible Causes for Arthralgia, Enlargement of the Spleen, Susceptibility to Hematologic Malignancies Increased

  • Gaucher Disease

    […] platelets (thrombocytopenia), lung disease, and bone abnormalities such as bone pain, fractures, and arthritis [ghr.nlm.nih.gov] (hepatomegaly) and enlarged spleen (splenomegaly[symptoma.com] In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] […] and EU Summary of Product Characteristics (SmPC) were evaluated with regard to frequency, drug-relatedness, severity, seriousness, duration, and timing of onset: headache, arthralgia[ncbi.nlm.nih.gov]

  • Common Variable Immunodeficiency

    Similarly, enlargement of the spleen is relatively common, as is enlargement of Peyer’s patches which are collections of lymphocytes in the walls of the intestine.[primaryimmune.org] […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com] Other findings less frequently reported included rash, arthralgias, myalgias, facial edema, and lymph node or liver test abnormalities, which can also occur in infectious[doi.org]

  • Hepatosplenomegaly

    Hepatosplenomegaly (Enlarged Liver and Spleen) What is Hepatosplenomegaly? Hepatomegaly is the medical term used to describe enlargement of spleen and liver.[primehealthchannel.com] […] infectious and parasitic Diseases, usually do not cause difficulty in diagnosis, as they are accompanied by characteristic history, marked symptoms of intoxication, fever, arthralgia[authorstream.com] She reported no rashes, arthralgia, dryness of eyes, mouth ulcers, or mucocutaneous bleeding. On examination she appeared pale and sweaty.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Schnitzler Syndrome

    The patient had also suffered from fever and right hip and left knee arthralgia.[ncbi.nlm.nih.gov] […] lymph nodes, spleen and/or liver, increased ESR, increased neutrophil count, abnormal bone imaging findings.[ncbi.nlm.nih.gov] Schnitzler syndrome is an autoinflammatory disease characterized by chronic, nonpruritic urticaria in association with recurrent fever, bone pain, arthralgia or arthritis,[emedicine.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Adult-Onset Still Disease

    […] lymph nodes (lymphadenopathy) Enlarged liver or spleen (hepatomegaly or splenomegaly) Abnormal liver function test Negative rheumatoid factor and negative ANA blood tests[dovemed.com] Severe malaise, myalgia, arthralgia, and leukocytosis were present in every patient.[ncbi.nlm.nih.gov] Arthralgia is usually correlated with fever spikes.[orpha.net]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Polycythemia Vera

    […] typically after a shower with warm water, but eventually during physical exercise, at bed time, or when changing cloths), headache, paresthesia, tinnitus, blurred vision, arthralgia[bloodjournal.org] Occasionally, the increased blood volume also causes congestion and enlargement of the spleen or liver.[uihc.org] Splenomegaly — Abnormal enlargement of the spleen. Splenomegaly is a major diagnostic criterion of PV.[medical-dictionary.thefreedictionary.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Myeloproliferative Disease

    Some different MPNs are described below: Enlargement of the spleen (splenomegaly) is common and occurs in around 75% of cases.[leukaemia.org.au] Treatment revolves around measures to maintain hydration, to relieve arthralgias, to prevent thrombotic episodes, and to prevent infections.[ncbi.nlm.nih.gov] Arthralgia and gout occur secondary to hyperuricemia.[symptoma.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Juvenile-Onset Still Disease

    There is also commonly swelling of the lymph glands, enlargement of the spleen and liver, and sore throat .[medicinenet.com] Among the 13 patients with “suspected” sJIA, 6 patients had neither arthralgia nor arthritis and 7 patients had arthralgia without ever having had arthritis.[ped-rheum.biomedcentral.com] There is also commonly swelling of the lymph glands, enlargement of the spleen and liver, and sore throat.[rxlist.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Leukemia

    […] lymph nodes Splenomegaly, which is an enlarged spleen Anemia, meaning low levels of red blood cells Thrombocytopenia, meaning low levels of platelets Hepatomegaly, which[cancer.net] Other side effects included rashes in 4%, arthralgias in 5%, and fatigue in 3%.[web.archive.org] Radiation therapy Radiation therapy may be used to destroy leukemia cells, or to relieve pain or discomfort caused by an enlarged liver or spleen, or swollen lymph nodes.[cancercenter.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Felty's Syndrome

    Splenomegaly is a condition of the spleen causing it to be enlarged.[en.wikipedia.org] Side effects included rare cases of thrombocytopenia, arthralgias, and development of cutaneous leukocytoclastic vasculitis.[ncbi.nlm.nih.gov] Case report A 17-year-old female with a 2-year history of erosive nodular seropositive RA followed Chinese herbal treatment for symptoms of repeated arthralgia in 2011.[spandidos-publications.com]

    Missing: Susceptibility to Hematologic Malignancies Increased

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