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3,178 Possible Causes for Arthralgia, Gammaglobulins Decreased, Susceptibility to Hematologic Malignancies Increased

  • Common Variable Immunodeficiency

    […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com] Other findings less frequently reported included rash, arthralgias, myalgias, facial edema, and lymph node or liver test abnormalities, which can also occur in infectious[doi.org] […] malignant diseases. 15 Although the majority of CVID cases occur sporadically, family history is helpful in securing the correct diagnosis. 15 Known immunodeficiency, unusual susceptibility[mdedge.com]

  • X-Linked Agammaglobulinemia

    Consequently, patients with XLA show significant decreases in gammaglobulin.[ncbi.nlm.nih.gov] Data from the USIDNET Registry on 149 patients with XLA, revealed that 12% had pain, swelling or arthralgias, while 18% had been diagnosed with arthritis.[ncbi.nlm.nih.gov] Since the mid-1980s, when gammaglobulin substitution therapy became available, the incidence of chronic enteroviral infection has markedly decreased in individuals with XLA[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Lupus Erythematosus

    . • Serum protein electrophoresis : increased gammaglobulin and decreased albumin. • Routine blood counts: anemia and low platelet and white cell counts. • Routine blood chemistry[slideshare.net] MUSCULOSKELETAL SYSTEM Musculoskeletal involvement is present in 95% of patients with SLE and manifests as arthralgias, myalgias, or nonerosive inflammatory arthritis. 10[aafp.org] Antimalarials, e.g., hydroxychloroquine, can use to treat arthralgia and skin disease.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Nephrotic Syndrome

    Six weeks later, along with steroid dose reduction, the symptoms of arthralgia was observed, which was managed with methotrexate.[ncbi.nlm.nih.gov] Fluid retention may cause Dyspnea (pleural effusion or laryngeal edema) Arthralgia (hydrarthrosis) Abdominal pain (ascites or, in children, mesenteric edema) Corresponding[merckmanuals.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Chronic Lymphocytic Leukemia

    Antibiotics are used to combat bacterial infections usually related to a decrease in the number of leukocytes (lymphopenia) and a low level of gammaglobulin in the blood.[rarediseases.org] As the causality ibrutinib-arthralgia seems legitimate, we expect further similar cases to surface in patients treated with Bruton tyrosine kinase inhibitors.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Multiple Myeloma

    […] uninvolved gammaglobulin levels). 21 At 5 years, progression free survival for SMM patients with 0, 1, and 2 risk factors is 4%, 46%, and 72%, respectively ( Table 2 ). 21[doi.org] The most common symptoms are joint pain (arthralgia), pain and numbness in the fingers and toes in response to cold (Raynaud’s phenomenon), weakness, and purpura.[rarediseases.org] Symptoms include fever, chills, arthralgia, myalgia, facial flushing, facial edema, vomiting, weakness, shortness of breath, hypotension, syncope, chest tightness, or angina[investors.amgen.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Common Cold

    These medications effectively relieve pain from headache, myalgias, and arthralgias experienced during a cold; however, decreased sneezing is the only effect they have on[aafp.org]

    Missing: Gammaglobulins Decreased Susceptibility to Hematologic Malignancies Increased
  • Gaucher Disease

    […] and EU Summary of Product Characteristics (SmPC) were evaluated with regard to frequency, drug-relatedness, severity, seriousness, duration, and timing of onset: headache, arthralgia[ncbi.nlm.nih.gov] In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] […] infusion reactions such as urticaria, arthralgia, headache, and chest pain due to IV administration.[symptoma.com]

    Missing: Gammaglobulins Decreased
  • Behçet Disease

    […] the appearance of side effects. 8 From our first case it seems that gammaglobulin may have a role in presurgical and postsurgical management of BD patients.[doi.org] Features such as arthralgia and leucocytoclastic vasculitis suggest an immune-complex mediated basis, which is supported by finding circulating immune complexes and, although[ncbi.nlm.nih.gov] […] of characteristics, including genetic background, clinical manifestations, and therapeutic strategies, especially the extraintestinal manifestations, such as oral ulcers, arthralgia[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Discoid Lupus Erythematosus

    . • Serum protein electrophoresis : increased gammaglobulin and decreased albumin. • Routine blood counts: anemia and low platelet and white cell counts. • Routine blood chemistry[slideshare.net] Up to 50% of patients with subacute cutaneous LE may also have a mild form of SLE, resulting in arthralgia (painful joints) or arthritis (joint disease) and low blood counts[dermnetnz.org] SLE may develop abruptly with fever or insidiously over months or years with episodes of arthralgias and malaise.[merckmanuals.com]

    Missing: Susceptibility to Hematologic Malignancies Increased

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