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227 Possible Causes for Arthralgia, Hypercellular Bone Marrow

  • Leukemia

    Other side effects included rashes in 4%, arthralgias in 5%, and fatigue in 3%.[web.archive.org] Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Myeloproliferative Disease

    Treatment revolves around measures to maintain hydration, to relieve arthralgias, to prevent thrombotic episodes, and to prevent infections.[ncbi.nlm.nih.gov] The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[clinlabnavigator.com] Arthralgia and gout occur secondary to hyperuricemia.[symptoma.com]

  • Chronic Myeloid Leukemia

    Among adult patients, 15–20% may suffer from mild joint pains. 16 Arthralgia was probably the most debilitating toxicity in our patients, forcing therapy alterations.[haematologica.org] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Decreased appetite 6/103 (5.83%) 6 Hyperglycaemia 6/103 (5.83%) 8 Hyperuricaemia 10/103 (9.71%) 20 Hypokalaemia 6/103 (5.83%) 7 Musculoskeletal and connective tissue disorders Arthralgia[clinicaltrials.gov]

  • Polycythemia Vera

    […] typically after a shower with warm water, but eventually during physical exercise, at bed time, or when changing cloths), headache, paresthesia, tinnitus, blurred vision, arthralgia[bloodjournal.org] bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Acute Leukemia

    Bone pain, arthralgia, and/or arthritis may manifest as decreased activity, general fussiness, irritability, or refusal to walk.[clinicaladvisor.com] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Bone marrow aspirate examination revealed hypercellularity with 70% blast cells.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    Sickle cell disease (SCD) usually manifests early in childhood. For the first 6 months of life, infants are protected largely by elevated levels of Hb F; soon thereafter, the condition becomes evident. The most common clinical manifestation of SCD is vaso-occlusive crisis. A vaso-occlusive crisis occurs when the[…][emedicine.medscape.com]

  • Chronic Neutrophilic Leukemia

    bone marrow with predominant neutrophilic granulopoiesis (M:E is 20:1 or more), the number of myeloblasts and promyelocytes is not increased, myelocytes and mature neutrophils[atlases.muni.cz] These cases are characterized by a high number of mature neutrophils in peripheral blood (PB), a hypercellular bone marrow due to neutrophilic granulocyte proliferation and[learningcenter.ehaweb.org] marrow Hypercellular bone marrow biopsy with increased neutrophils showing no overt dysplasia, normal megakaryocytes Hepatosplenomegaly No reactive cause for neutrophilia[clinicaladvisor.com]

  • Myelodysplasia

    […] recognized Bilineage dysplasia Clinical Presentation May be asymptomatic Most common symptoms Pallor, weakness, exertional dyspnea – secondary to anemia Hepatomegaly/splenomegaly Arthralgias[arupconsult.com] bone marrow Hello all, On my BMB report, for the bone marrow, it states "hypercellular ... 3 days, 8 hours ago CENTERS OF EXCELLENCE Would you like your treatment center[mds-foundation.org] The patient's medical history was significant for a three-year history of an uncharacterized rheumatologic illness marked by myalgias, arthralgias, two episodes of iridocyclitis[casesjournal.biomedcentral.com]

  • Paraneoplastic Syndrome

    Sweet’s Syndrome  Acute febrile neutrophilic dermatosis  Associated with leukemia  Acute tender red nodules or plaques  Fever, arthralgia, oral lesions, eye involvement[slideshare.net] Pancytopenia with a hypercellular bone marrow as a possible paraneoplastic syndrome. Am. J. Hematol. 19, 205–206 (1985). 37. Cooper, D. L., Sandler, A. B., Wilson, L.[doi.org] Inflammation of the heart (myocarditis), joints (arthralgias), and lungs (interstitial lung disease) can occur.[rarediseases.org]

  • Schnitzler Syndrome

    The patient had also suffered from fever and right hip and left knee arthralgia.[ncbi.nlm.nih.gov] Bone marrow biopsy revealed a hypercellular (70%) marrow characterized by trilineage hematopoietic maturation with an increased granulocyte:erythroid ratio.[omicsonline.org] Schnitzler syndrome is an autoinflammatory disease characterized by chronic, nonpruritic urticaria in association with recurrent fever, bone pain, arthralgia or arthritis,[emedicine.com]

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