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3,322 Possible Causes for Arthralgia, Immunoglobulin G Decreased, Severe Recurrent Orthostatic Hypotension

  • Amyloidosis

    Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org] […] with AL amyloidosis, but AA amyloidosis has also been reported. 39 Hepato/splenomegaly in patients with Schnitzler syndrome (IgM monoclonal gammopathy, urticarial rash, arthralgia[bloodjournal.org] To target residual bound SAP, anti SAP immunoglobulin-G (IgG) antibodies have been generated [ 55 ].[doi.org]

  • Chronic Myeloid Leukemia

    Among adult patients, 15–20% may suffer from mild joint pains. 16 Arthralgia was probably the most debilitating toxicity in our patients, forcing therapy alterations.[haematologica.org] Decreased appetite 6/103 (5.83%) 6 Hyperglycaemia 6/103 (5.83%) 8 Hyperuricaemia 10/103 (9.71%) 20 Hypokalaemia 6/103 (5.83%) 7 Musculoskeletal and connective tissue disorders Arthralgia[clinicaltrials.gov] […] cardiovascular events, in particular peripheral arterial disease, was noted, although many affected patients had predisposing risk factors. 111 About 19% of all patients experience arthralgia[haematologica.org]

    Missing: Severe Recurrent Orthostatic Hypotension
  • Hypogammaglobulinemia

    Musculoskeletal symptoms Arthralgia and monoarticular or oligoarticular arthritis of the large joints with sterile effusions occasionally occur.[emedicine.medscape.com] Evaluation unexpectedly revealed hypogammaglobulinemia [decreased immunoglobulin G (IgG), IgM, and IgA].[ncbi.nlm.nih.gov] Arthralgia, monoarticular or oligoarticular arthritis of the large joints with sterile effusions and septic arthritis may occur.[patient.info]

    Missing: Severe Recurrent Orthostatic Hypotension
  • Common Variable Immunodeficiency

    Other findings less frequently reported included rash, arthralgias, myalgias, facial edema, and lymph node or liver test abnormalities, which can also occur in infectious[doi.org] […] serum levels of immunoglobulin G (IgG) and immunoglobulin A (IgA) are characteristic of the disorder, about 50% of CVID patients also have decreased immunoglobulin M (IgM[medigoo.com] This disturbance manifests in decreased levels of immunoglobulin (Ig) G, IgA, and, sometimes, IgM isotypes and in an impaired or even absent antibody response upon antigenic[the-rheumatologist.org]

    Missing: Severe Recurrent Orthostatic Hypotension
  • X-Linked Agammaglobulinemia

    Data from the USIDNET Registry on 149 patients with XLA, revealed that 12% had pain, swelling or arthralgias, while 18% had been diagnosed with arthritis.[ncbi.nlm.nih.gov] G (IgG) levels decrease below protective levels in infants.[intechopen.com] A decreased number of circulating B cells and low levels of all immunoglobulin subtypes were consistent with agammaglobulinemia (immunoglobulin A 16mg/dL [normal range 81–[jcadonline.com]

    Missing: Severe Recurrent Orthostatic Hypotension
  • Cartilage Hair Hypoplasia

    Clinical and immunological data are presented in a thirteen-year-old girl with cartilage-hair hypoplasia. From early infancy, the girl suffered from recurrent respiratory infections, and at ten years of age she had a severe and protracted attack of varicella. Immunologic investigations revealed very low mitogenic[…][ncbi.nlm.nih.gov]

    Missing: Severe Recurrent Orthostatic Hypotension
  • Primary Amyloidosis

    Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org] […] para-protein (IgM-κ is most common) at the dermoepidermal junction and in capillary walls which probably contributes to development of chronic urticaria, intermittent fever, arthralgia[doi.org] Further laboratory studies revealed decreased serum immunoglobulin levels (IgA 0.35 g/L, reference value 0.7-3.8 g/L; IgM 0.26 g/L, reference value 0.6-2.5 g/L), elevated[bmcgastroenterol.biomedcentral.com]

  • Systemic Amyloidosis

    recurrent inflammation. 57 Supportive treatment of specific symptoms Although symptoms of dysautonomia are rare in AA amyloidosis, severe orthostatic hypotension may lead[ncbi.nlm.nih.gov] […] para-protein (IgM-κ is most common) at the dermoepidermal junction and in capillary walls which probably contributes to development of chronic urticaria, intermittent fever, arthralgia[doi.org] […] with AL amyloidosis, but AA amyloidosis has also been reported. 39 Hepato/splenomegaly in patients with Schnitzler syndrome (IgM monoclonal gammopathy, urticarial rash, arthralgia[bloodjournal.org]

  • Cutaneous Leukocytoclastic Vasculitis

    The patient sought emergency treatment presenting with headache, arthralgia, cutaneous rash, and weight loss (4 kg) in the last 20 days.[ncbi.nlm.nih.gov] Serum concentrations of immunoglobulin G decreased and plasma cells in bone marrow decreased.[ncbi.nlm.nih.gov] Arthralgia occurred in 20 per cent of the patients.[ncbi.nlm.nih.gov]

    Missing: Severe Recurrent Orthostatic Hypotension
  • Lupus Nephritis

    Both dengue fever and SLE have common manifestations of fever, arthralgia, rash, leucopenia with thrombocytopenia and serositis.[ncbi.nlm.nih.gov] A 25-year-old woman presented with fever, arthralgia and proteinuria exhibiting leukopenia, hypocomplementemia, increased serum IgG and IgG4, and positive antinuclear and[ncbi.nlm.nih.gov] […] white male on methimazole due to Grave's thyroiditis presented with acute renal failure after a short term history of progressive shortness of breath, malaise, myalgias, arthralgias[ncbi.nlm.nih.gov]

    Missing: Severe Recurrent Orthostatic Hypotension

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