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3,247 Possible Causes for Arthralgia, Immunoglobulin G Decreased, Susceptibility to Hematologic Malignancies Increased

  • Common Variable Immunodeficiency

    […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com] Other findings less frequently reported included rash, arthralgias, myalgias, facial edema, and lymph node or liver test abnormalities, which can also occur in infectious[doi.org] […] serum levels of immunoglobulin G (IgG) and immunoglobulin A (IgA) are characteristic of the disorder, about 50% of CVID patients also have decreased immunoglobulin M (IgM[medigoo.com]

  • Amyloidosis

    […] with AL amyloidosis, but AA amyloidosis has also been reported. 39 Hepato/splenomegaly in patients with Schnitzler syndrome (IgM monoclonal gammopathy, urticarial rash, arthralgia[bloodjournal.org] To target residual bound SAP, anti SAP immunoglobulin-G (IgG) antibodies have been generated [ 55 ].[doi.org] Clinical features : The most frequent manifestations include cutaneous purpura and urticaria; in many cases there are weakness and arthralgias.[kidneypathology.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Chronic Myeloid Leukemia

    Among adult patients, 15–20% may suffer from mild joint pains. 16 Arthralgia was probably the most debilitating toxicity in our patients, forcing therapy alterations.[haematologica.org] Decreased appetite 6/103 (5.83%) 6 Hyperglycaemia 6/103 (5.83%) 8 Hyperuricaemia 10/103 (9.71%) 20 Hypokalaemia 6/103 (5.83%) 7 Musculoskeletal and connective tissue disorders Arthralgia[clinicaltrials.gov] […] cardiovascular events, in particular peripheral arterial disease, was noted, although many affected patients had predisposing risk factors. 111 About 19% of all patients experience arthralgia[haematologica.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Hypogammaglobulinemia

    Musculoskeletal symptoms Arthralgia and monoarticular or oligoarticular arthritis of the large joints with sterile effusions occasionally occur.[emedicine.medscape.com] Evaluation unexpectedly revealed hypogammaglobulinemia [decreased immunoglobulin G (IgG), IgM, and IgA].[ncbi.nlm.nih.gov] Arthralgia, monoarticular or oligoarticular arthritis of the large joints with sterile effusions and septic arthritis may occur.[patient.info]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • X-Linked Agammaglobulinemia

    Data from the USIDNET Registry on 149 patients with XLA, revealed that 12% had pain, swelling or arthralgias, while 18% had been diagnosed with arthritis.[ncbi.nlm.nih.gov] G (IgG) levels decrease below protective levels in infants.[intechopen.com] A decreased number of circulating B cells and low levels of all immunoglobulin subtypes were consistent with agammaglobulinemia (immunoglobulin A 16mg/dL [normal range 81–[jcadonline.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Cartilage Hair Hypoplasia

    Cartilage hair hypoplasia is a rare multisystemic genetic disorder demarcated by a short stature from birth, hypoplastic hair, various skeletal abnormalities and a variable degree of immunodeficiency that can be fatal in the absence of an early diagnosis. Clinical signs, results from imaging studies, and genetic testing[…][symptoma.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Cutaneous Leukocytoclastic Vasculitis

    The patient sought emergency treatment presenting with headache, arthralgia, cutaneous rash, and weight loss (4 kg) in the last 20 days.[ncbi.nlm.nih.gov] Serum concentrations of immunoglobulin G decreased and plasma cells in bone marrow decreased.[ncbi.nlm.nih.gov] Arthralgia occurred in 20 per cent of the patients.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Lupus Nephritis

    Both dengue fever and SLE have common manifestations of fever, arthralgia, rash, leucopenia with thrombocytopenia and serositis.[ncbi.nlm.nih.gov] A 25-year-old woman presented with fever, arthralgia and proteinuria exhibiting leukopenia, hypocomplementemia, increased serum IgG and IgG4, and positive antinuclear and[ncbi.nlm.nih.gov] […] white male on methimazole due to Grave's thyroiditis presented with acute renal failure after a short term history of progressive shortness of breath, malaise, myalgias, arthralgias[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Hepatitis

    ., fatigue, arthralgia, jaundice) in approximately one third of patients; however, the majority of patients are asymptomatic.[bestpractice.bmj.com] These changes were made because of concerns about decreased HAV immunoglobulin G antibody (anti-HAV IgG) potency, likely resulting from decreasing prevalence of previous HAV[cdc.gov] Arthralgia involving small joints is common, and inflammatory arthritis may be particularly troublesome.[doi.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Immune Thrombocytopenic Purpura

    A 30-year-old Colombian woman with past history of immune thrombocytopenia (ITP) presented to the emergency room with two days of global headache, arthralgia, myalgia, and[ncbi.nlm.nih.gov] It is mediated by immune mechanisms, in most cases immunoglobulin g autoantibodies which attach to platelets and subsequently undergo destruction by macrophages.[icd10data.com] Nausea/vomiting and arthralgia/musculoskeletal pain were most common across treatments, and hemolytic events did not differ significantly across treatments.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased

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