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82 Possible Causes for Arthralgia, Iron Increased, Reticulocyte Count Decreased

  • Aplastic Anemia

    For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow .[labtestsonline.org] We studied 4 adult AA patients who had transfusion-induced iron overload and showed hematological improvement after ICT with oral deferasirox.[ncbi.nlm.nih.gov] Stainable iron is usually increased; however, the presence of increased ringed sideroblasts suggests a diagnosis of MDS.[cancertherapyadvisor.com]

  • Leukemia

    Other side effects included rashes in 4%, arthralgias in 5%, and fatigue in 3%.[web.archive.org]

  • Acute Myelocytic Leukemia

    […] peripheral blood progenitor cell mobilization and collection are bone pain, pyrexia, increased blood alkaline phosphatase, and headache with severe chronic neutropenia are arthralgia[neupogenhcp.com] An iron stain usually shows increased iron stores and may show ring sideroblasts (Figure 2, B [inset]).[archivesofpathology.org] The potential for neurotoxicity has aroused concern about the use of high-dose cytarabine in elderly patients who, ironically, have a higher likelihood of having drug-resistant[doi.org]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    Mitochondrial pathology in MDS is suggested by abnormal mitochondrial iron accumulation, increased apoptosis, and a high frequency of acquired mitochondrial DNA mutations[ncbi.nlm.nih.gov]

  • Iron Deficiency Anemia

    Normal 0.5-1.5% Hypoprolifearative: Decreased reticulocytes Bone marrow unable to produce requisite number of RBC's Lack of essential substance (iron, B12, folate) or invasion[meddean.luc.edu] There also is a delayed reaction, which consists of myalgias, headache, and arthralgias, that can occur 24 to 48 hours after infusion.[aafp.org] This is because your need for iron increases during these times of growth and development.[web.archive.org]

  • Myelodysplasia

    […] recognized Bilineage dysplasia Clinical Presentation May be asymptomatic Most common symptoms Pallor, weakness, exertional dyspnea – secondary to anemia Hepatomegaly/splenomegaly Arthralgias[arupconsult.com] Red blood cells contain iron, so if you have a lot of blood transfusions, the level of iron in your body will increase.[macmillan.org.uk] The patient's medical history was significant for a three-year history of an uncharacterized rheumatologic illness marked by myalgias, arthralgias, two episodes of iridocyclitis[casesjournal.biomedcentral.com]

  • Sideroblastic Anemia

    RBC indices reveal a decreased MCV, MCH, and a decreased reticulocyte count which correlates with Iron deficiency anemia.[usmleforum.com] THE CASE A 46-year-old Caucasian female with a history of epilepsy came into our family medicine center complaining of weakness, fatigue, and arthralgia that made it difficult[mdedge.com] Decreased ferritin increases synthesis of transferrin (increasing TIBC); such as seen in iron deficiency anemia.[forums.studentdoctor.net]

  • Addison's Disease

    […] has an insidious onset and presents with many non-specific symptoms and signs: - Weakness and fatigability (99%), anorexia (99%), nausea/vomiting, abdominal pain, myalgias/arthralgias[clinicaladvisor.com] Imaging X-ray or CT Evidence of Calcification in adrenal area Renal TB Pulmonary TB Hyperpigmentation can result from bronchogenic carcinoma, ingestion of heavy metals (eg, iron[merckmanuals.com] […] fasting 50 mg/dL ( 2.78 mmol/L) Plasma bicarbonate 15–20 mEq/L BUN 20 mg/dL ( 7.1 mmol/L) Hematology Hct Elevated WBC count Low Lymphocytes Relative lymphocytosis Eosinophils Increased[merckmanuals.com]

  • Myeloproliferative Disease

    Treatment revolves around measures to maintain hydration, to relieve arthralgias, to prevent thrombotic episodes, and to prevent infections.[ncbi.nlm.nih.gov] […] mean normal predicted value. 9.  Increased RBC count and Hgb levels (except when iron deficient)  Elevated RBC mass  Panmyelosis in the bone marrow  Low EPO level  Positive[slideshare.net] Arthralgia and gout occur secondary to hyperuricemia.[symptoma.com]

  • Erythema Infectiosum

    , a decrease in the reticulocyte count to less than 1% (usually to 0%) may precipitate TAC.[emedicine.com] Leg pain and arthralgia occurred in five of the children.[ncbi.nlm.nih.gov] […] red cell loss - eg, sickle cell anaemia, thalassaemia, hereditary spherocytosis and iron-deficiency anaemia.[patient.info]

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