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3,316 Possible Causes for Arthralgia, Normal T Cell Numbers, Susceptibility to Hematologic Malignancies Increased

  • Gaucher Disease

    In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] […] and EU Summary of Product Characteristics (SmPC) were evaluated with regard to frequency, drug-relatedness, severity, seriousness, duration, and timing of onset: headache, arthralgia[ncbi.nlm.nih.gov] Dendritic cells in patients with type I Gaucher disease are decreased in number but functionally normal.[ncbi.nlm.nih.gov]

  • Common Variable Immunodeficiency

    Specifically, T cells from these patients did not differ from normal persons in total T-cell number or CD4/CD8 ratio.[annals.org] Other findings less frequently reported included rash, arthralgias, myalgias, facial edema, and lymph node or liver test abnormalities, which can also occur in infectious[doi.org] […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com]

  • Influenza

    This is a case of a 60-year-old man with chronic idiopathic pulmonary fibrosis, with fever, arthralgias and rash characterised by extensive erythematous plaques on his limbs[ncbi.nlm.nih.gov] Our data demonstrate that primary and secondary cytotoxic responses against influenza virus-infected cells by CD8 T cells in the BAL and lung draining lymph nodes, respectively[doi.org] We defined RIDT-negative influenza-like illness as RIDT-negative cases suspected by doctors due to clinical signs such as fever, headache, arthralgia, runny nose, and/or coughing[doi.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Psoriasis

    […] case, the skin tightening was successfully improved and ustekinumab was more effective, even though oral prednisolone (9-12 mg/day) had some effect on skin tightening and arthralgia[ncbi.nlm.nih.gov] After culturing dermal DC with allogenic CD4 T cells, psoriatic DCs induced a far greater number of CD4 T cells to produce IL-17 compared with normal dermal DCs [ 34 ].[web.archive.org] Patients may have a preceding history of psoriasis, although this is not a requirement. [11] Constitutional signs and symptoms include headache, fever, chills, arthralgia,[emedicine.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Polymyalgia Rheumatica

    The systemic inflammatory systems of WG, including arthralgias, may mimic other conditions such as PMR.[ncbi.nlm.nih.gov] . 18 T-cell depletion is not found consistently, however, in polymyalgia rheumatica.[reliasmedia.com] METHODS: This was a retrospective study of patients receiving an ICI in whom symptoms of arthritis or arthralgia developed and revealed a diagnosis of RA or PMR.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Sarcoidosis

    , such as diabetes mellitus and multiple sclerosis. w24 Patients with Lofgren’s syndrome have normal numbers of natural killer cells, which may explain why their prognosis[doi.org] Other symptoms include anterior uveitis, fever, ankle periarthritis, arthralgias, and pulmonary involvement.[emedicine.medscape.com] In addition, the blood of sarcoidosis patients contains a reduced number of T-cells.[medicinenet.com]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • HIV Infection

    Although some patients with acute HIV-1 infection experience fever, lymphadenopathy, pharyngitis, skin rash, myalgia, arthralgia, and other symptoms, 1-6 a recent prospective[aidsinfo.nih.gov] During this time, untreated HIV will be killing CD4 T-cells and destroying your immune system.[webmd.com] Prospective studies of acute HIV infections show that fever, lymphadenopathy, pharyngitis, diffuse erythematous rash, arthralgia/myalgia, diarrhea, and headache are the commonest[library.med.utah.edu]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Leukemia

    […] capacity is higher in T-prolymphocytes compared with normal T cells or cells from other mature T-cell malignancies, and it is similar or close to that of T-cell acute lymphoblastic[web.archive.org] Other side effects included rashes in 4%, arthralgias in 5%, and fatigue in 3%.[web.archive.org] The monoclonal antibodies CD2 and CD5 are usually positive, and CD7 is strongly expressed in most cases. 9 The number of CD7 antigenic determinants estimated by the antibody-binding[web.archive.org]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Inflammatory Bowel Disease Type 1

    Importantly, normal thymic T cell development, together with unaltered T and B cell numbers in the spleen, demonstrated that food antigen deficiency does not disturb systemic[jci.org] The authors present the case of a 22-year-old female patient that was admitted to their hospital due to diarrhea, fever, arthralgias, and diffuse erythematous papules and[ncbi.nlm.nih.gov] A 58-year-old woman presented with recent peripheral inflammatory arthralgias appeared in the context of a Crohn's disease diagnosed in 2008.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased
  • Celiac Disease

    After three weeks she developed other symptoms such as arthralgias, malar rash, being finally diagnosed with SLE and possible autoimmune hepatitis.[ncbi.nlm.nih.gov] Numbers of T cell receptor (TCR) αβ but not TcR γδ intraepithelial lymphocytes correlate with the grade of villous atrophy in coeliac patients on a long term normal diet.[doi.org] BACKGROUND: Familial Mediterranean fever and celiac disease share some common clinical features such as abdominal pain, diarrhea, arthralgia and arthritis.[ncbi.nlm.nih.gov]

    Missing: Susceptibility to Hematologic Malignancies Increased

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