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3,756 Possible Causes for Arthralgia, Onset of Symptoms in the Fourth to Sixth Decade of Life, Xerostomia

  • Hemochromatosis

    Symptoms greatly vary among patients and include fatigue, abdominal pain, arthralgias, impotence, decreased libido, diabetes, and heart failure.[ncbi.nlm.nih.gov] […] and its full clinical expression is seen in only a minority of patients. [9] In addition, any patient admitted to the hospital with an isolated case of asthenia or with arthralgia[emedicine.com] The prevalences of fatigue, arthralgia and abnormal liver test results were higher in our group (85.5 vs 36.1%; 78.3 vs 24.4% and 46.6 vs 16.8%).[nature.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Sjögren Syndrome

    Sjogren's syndrome, involving sicca symptoms with xerostomia, stomatitis, and considerable pain is a difficult-to-treat autoimmune disease where the treatment options are[ncbi.nlm.nih.gov] The most difficult challenge in diagnosis and therapy is patients with symptoms of fibromyalgia (arthralgia, myalgia, fatigue) and oral and ocular dryness in the presence[ncbi.nlm.nih.gov] The clinical manifestations evaluated were defined as follows: Articular involvement: arthralgia and/or nonerosive arthritis characterized by tenderness, swelling, or effusion[doi.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Rheumatoid Arthritis

    Sjogren’s syndrome is an autoimmune condition that affects exocrine gland function, leading to a reduction in tear production (keratoconjunctivitis sicca), oral dryness (xerostomia[hopkinsarthritis.org] It can cause arthralgias and weakness in intrinsic muscles of the hand.[ncbi.nlm.nih.gov] Sjögren’s syndrome used in this and other studies, 36, 37 the frequency of the diagnosis depends heavily on the availability of specific tests for the evaluation of possible xerostomia[doi.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Systemic Scleroderma

    (SSc) is an autoimmune disease that affects connective tissue, resulting in hardening skin, reduced vascular perfusion, gingival fibrosis, enlarged periodontal ligament, xerostomia[ncbi.nlm.nih.gov] Musculoskeletal Joint pain can be either arthralgia or myalgia. The terms arthralgia and myalgia are often used in combination or interchangeably.[sclerodermasociety.co.uk] SSc patients complained more frequently (78.8%) of oral symptoms (Xerostomia, dysgeusia, dysphagia and stomatodynia) than controls (28.7%) (χ² 40.23 p 0.001).[ncbi.nlm.nih.gov]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Diffuse Scleroderma

    Muscle weakness Muscular weakness 0001324 Osteolysis Breakdown of bone 0002797 Pulmonary fibrosis 0002206 Skin ulcer Open skin sore 0200042 Telangiectasia of the skin 0100585 Xerostomia[rarediseases.info.nih.gov] Musculoskeletal Joint pain can be either arthralgia or myalgia. The terms arthralgia and myalgia are often used in combination or interchangeably.[sclerodermasociety.co.uk] The Raynaud phenomenon, swelling of the extremities, and diffuse arthralgias often precede the onset... FULL TEXT[doi.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Primary Biliary Cirrhosis

    She was 38 years old and was admitted to our hospital for generalized pruritus, xerostomia, xerophthalmia, fatigue, and reticulonodular changes on her chest X-ray.[ncbi.nlm.nih.gov] We report the case of a 53-year-old patient who presented with weakness, myalgia, arthralgia, shortness of breath and purpura.[ncbi.nlm.nih.gov] Pinto A: Management of xerostomia and other complications of Sjögren's syndrome. Oral Maxillofac Surg Clin North Am 2014;26:63-73.[karger.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Amyloidosis

    Areas of swelling, hemorrhages under the skin (purpura), hair loss (alopecia), inflammation of the tongue (glossitis) and a dry mouth (xerostomia) may also be present.[rarediseases.org] […] with AL amyloidosis, but AA amyloidosis has also been reported. 39 Hepato/splenomegaly in patients with Schnitzler syndrome (IgM monoclonal gammopathy, urticarial rash, arthralgia[bloodjournal.org] Clinical features : The most frequent manifestations include cutaneous purpura and urticaria; in many cases there are weakness and arthralgias.[kidneypathology.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Temporal Arteritis

    […] ophthalmic artery and its branches are affected, is characterized by the formation of giant cells, and may be accompanied by fever, malaise, fatigue, anorexia, weight loss, and arthralgia[merriam-webster.com] In NAION, patients will usually not note any associated systemic symptoms such as headache, jaw claudication, scalp tenderness, weight loss, anorexia, fever, or myalgias/arthralgias[eyewiki.aao.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Stomatitis

    Incidences of AEs of interest (days 1-42) were arthralgia (17.1% combined lots, 20.4% high-dose, 3.0% placebo), arthritis (5.1% combined lots, 4.2% high-dose, 0.0% placebo[ncbi.nlm.nih.gov] Xerostomia was significantly more common and severe in patients (46.9%) than in healthy controls, whereas the saliva flow rates did not differ.[ncbi.nlm.nih.gov] Five participants had an onset of arthralgia 7 to 14 days after vaccination, and 3 participants had arthralgia that began after the second vaccination.[nejm.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Polyarthritis

    Two patients also developed xerostomia and xerostomia, and laboratory test results showed normal values of CRP and erythrocyte sedimentation rate.[ncbi.nlm.nih.gov] Although bisphosphonates are safety drugs, they have numerous side-effects such as arthralgia, elevated erythrocyte sedimentation rate and C-reactive protein, gastrointestinal[ncbi.nlm.nih.gov] Alphavirus Polyarthritis Syndrome has an incubation period of 3–21 days, depending on the specific virus, with either a gradual or sudden onset of fever, arthralgias, headache[en.wikipedia.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life

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