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16 Possible Causes for Arthralgia, Severe Recurrent Orthostatic Hypotension, Weight Loss

  • Amyloidosis

    Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org] MGUS and myeloma patients that have atypical features, including unexplained weight loss; lower extremity edema, early satiety, and dyspnea on exertion should be considered[ncbi.nlm.nih.gov] […] with AL amyloidosis, but AA amyloidosis has also been reported. 39 Hepato/splenomegaly in patients with Schnitzler syndrome (IgM monoclonal gammopathy, urticarial rash, arthralgia[bloodjournal.org]

  • Primary Amyloidosis

    Orthostatic hypotension can be severe and difficult to manage. Fitted waist-high elastic stockings and midodrine are helpful.[doi.org] She came to the gastroenterology clinics complaining of hematochezia, weight loss, decreased appetite and abdominal pain.[ncbi.nlm.nih.gov] […] para-protein (IgM-κ is most common) at the dermoepidermal junction and in capillary walls which probably contributes to development of chronic urticaria, intermittent fever, arthralgia[doi.org]

  • Systemic Amyloidosis

    recurrent inflammation. 57 Supportive treatment of specific symptoms Although symptoms of dysautonomia are rare in AA amyloidosis, severe orthostatic hypotension may lead[ncbi.nlm.nih.gov] Later, she developed dyspepsia and weight loss. An oesophagogastroduodenoscopy (OGD) showed Helicobacter pylori negative erosive gastritis with a benign duodenal ulcer.[ncbi.nlm.nih.gov] […] para-protein (IgM-κ is most common) at the dermoepidermal junction and in capillary walls which probably contributes to development of chronic urticaria, intermittent fever, arthralgia[doi.org]

  • Acute Pandysautonomia

    Patient 6 had a history of recurrent ileus and severe abdominal pain.[journals.plos.org] The cause of this disorder is unknown, although both patients had undergone substantial weight loss.[ncbi.nlm.nih.gov] Additional features of the cryoglobulinemic syndrome include purpura, skin ulcers, arthralgias, sicca syndrome, Raynaud’s phenomenon, glomerulonephritis, and lymphadenopathy[mjhid.org]

  • Capillary Leak Syndrome

    . - A man aged 61 had recurrent attacks of severe shock.[ntvg.nl] In the post-leak phase, massive edema resorption leads to polyuria and weight loss.[orpha.net] The most common side effects of IL-11 are arthralgias and myalgias, fatigue, nausea, and headache.[cancerjournal.net]

  • Optic Nerve Edema-Splenomegaly Syndrome

    Complications such as severe orthostatic hypotension, recurrent infections or venous thromboses should be evaluated on the basis of resultant impairment. C.[secure.ssa.gov] loss,pills,weight loss tips yoga[sites.google.com] Ankle arthralgias are common.[autoinflammatory-search.org]

  • Dysautonomia

    Severe autonomic dysfunctions occur: alacrymia (loss of tear secretion), dysphagia, hypothermia, orthostatic hypotension, loss of fungiform papillas on tongue.[tankonyvtar.hu] loss without trying Signs of autonomic nerve damage are not always seen when your doctor examines you.[nlm.nih.gov] […] rapid heartbeat (tachycardia), excessive sweating (hyperhidrosis), perspiration depletion (anhidrosis), nerve pain or numbness (paresthesia or neuropathy), and joint pain (arthralgia[clinicalposters.com]

  • Idiopathic Bilateral Vestibulopathy

    Patients most often experience BPPV when lying down, which distinguishes BPPV from orthostatic hypotension. In addition, BPPV may be recurrent.[raleighcapitolent.com] loss, loss of interest). 4 Sustained depression with vegetative symptoms and suicidal thoughts or intent. 4.[books.google.it] […] purpura: With vasculitis, cutaneous or systemic Thymus hyperplasia Vasculopathies, other: Raynaud's (30%) Parotid swelling: Especially younger patients Discomfort: Myalgias ; Arthralgias[neuromuscular.wustl.edu]

  • Pure Autonomic Failure

    First, patients with PAF did not have severe urinary disturbances, which would lessen the risk of recurrent urinary infections, and they also did not have life threatening[jnnp.bmj.com] For approximately 2 years, the patient has been experiencing dizziness and a tendency to fall, a significant weight loss, generalized weakness, dysphagia, intestinal constipation[ncbi.nlm.nih.gov] […] foreign body in the eye, increased lacrimation (tear production), blepharitis (inflammation of the eyelids), dry eye, ocular hyperaemia (red eye), eye pruritis (itching), arthralgia[sv.glosbe.com]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    Severe autonomic dysfunctions occur: alacrymia (loss of tear secretion), dysphagia, hypothermia, orthostatic hypotension, loss of fungiform papillas on tongue.[tankonyvtar.hu] […] suppression Oxycarbazepine 600-2400 mg Fatigue, nausea, dizziness, leukopenia Lamotrigine 50-500 mg Serious rash, dizziness, nausea, sedation Topiramate 25-400 mg Sedation, weight[clevelandclinicmeded.com] […] for 3/12 in four or more joints Minor criteria Current/historic Brighton score of 1, 2 or 3/9 (0, 1, 2, 3/9 if 50 years old) Arthralgia for minimum of 3 months in 1–3 joints[medical-dictionary.thefreedictionary.com]

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