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11 Possible Causes for Arthralgia, Susceptibility to Hematologic Malignancies Increased

  • Gaucher Disease

    In addition to the classic manifestations, patients suffer from increased susceptibility to hematologic and nonhematologic malignancies.[ncbi.nlm.nih.gov] […] and EU Summary of Product Characteristics (SmPC) were evaluated with regard to frequency, drug-relatedness, severity, seriousness, duration, and timing of onset: headache, arthralgia[ncbi.nlm.nih.gov] […] infusion reactions such as urticaria, arthralgia, headache, and chest pain due to IV administration.[symptoma.com]

  • Common Variable Immunodeficiency

    […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com] Other findings less frequently reported included rash, arthralgias, myalgias, facial edema, and lymph node or liver test abnormalities, which can also occur in infectious[doi.org] […] malignant diseases. 15 Although the majority of CVID cases occur sporadically, family history is helpful in securing the correct diagnosis. 15 Known immunodeficiency, unusual susceptibility[mdedge.com]

  • Splenic Subcapsular Hematoma

    However, splenectomy should be avoided if possible, particularly in children, the elderly, and patients with hematologic malignancy, to avoid the resulting permanent susceptibility[merckmanuals.com] He reported no previous trauma, fever, headache, fatigue, myalgia, arthralgia, skin alterations, or comorbidities.[semanticscholar.org] Initially, our patient, a 65 year-old man, had nonspecific manifestations of fever, malaise, headache, anorexia and arthralgia which are the classic symptoms of this disease[read.qxmd.com]

  • Fungal Meningitis

    The patients most susceptible to invasive fungal infections include those with hematologic malignancies; those receiving hyperalimentation, corticosteroids, or cytotoxic drugs[ncbi.nlm.nih.gov] The presenting signs and symptoms may consist of the following: Photophobia Nausea and vomiting Myalgia Arthralgia Problems with coordination Drowsiness/Confusion Headache[symptoma.com] This increase is due to the availability of better diagnostic techniques for fungal infections and the ever-increasing population of immunocompromised hosts (1,2).[ncbi.nlm.nih.gov]

  • Parainfluenza Virus

    malignancy (HM) patients because of their immunocompromised status and susceptibility to lower respiratory tract infections.[ncbi.nlm.nih.gov] In addition, systemic symptoms such as myalgias and arthralgias were not seen in these patients, unlike patients with cytomegalovirus.[nejm.org] Advances in diagnostic methods, including polymerase chain reaction, have led to increased identification and awareness of these infections.[ncbi.nlm.nih.gov]

  • Autosomal Dominant Thrombocytopenia 5

    THC5 is an autosomal dominant disorder, associated with an increased susceptibility to the development of hematologic and solid malignancies.[uniprot.org] Rheumatoid factor and antinuclear antibody tests should be ordered if a patient has significant prominent arthralgia or arthritis.[aafp.org] Affected individuals have an increased susceptibility to the development of hematologic malignancies, and possibly to solid neoplasms.[malacards.org]

  • Monocytopenia with Susceptibility to Infections

    Most of the patients present with hematological abnormalities (cytopenias, early-onset myeloid malignancies) and an increased susceptibility to opportunistic infections [[bmcpulmmed.biomedcentral.com] Since approximately one third of patients may have rheumatologic symptoms, such as erythema nodosum, panniculitis, or arthralgias, rheumatologists may expect to encounter[link.springer.com] Contrary to previous findings from our institution (3), most patients with C. glabrata fungemia in the series re ported here had solid tumors rather than hematologic malignancies[thefreelibrary.com]

  • Methylprednisolone

    : Leukocytosis (transient), malignant neoplasm (secondary), petechia Hepatic: Hepatomegaly, increased liver enzymes, increased serum transaminases Hypersensitivity: Anaphylactoid[drugs.com] Henoch-Schönlein purpura is an immunoglobulin A-mediated, small vascular inflammatory disease that can be associated with palpable purpura, arthralgia, abdominal pain, or[ncbi.nlm.nih.gov] Common Growth retardation (in children); osteoporosis; muscular weakness Not known Osteonecrosis; pathological fracture; muscle atrophy; myopathy; neuropathic arthropathy; arthralgia[medicines.org.uk]

  • Common Variable Immunodeficiency Type 4

    […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com] arthralgia, symmetric polyarthritis polyarthralgia polyarthralgia, oligoarthritis, clubbig epiphyseal overgrowth, contractures, intermittent or chronic arthritis, clubbing[ufrgs.br] The adverse effects identified were: edema at the site of administration, fever, chills, malaise, exanthema, vertigo, arthralgia, vomiting, hematochezia, hair loss, phlogistic[scitechnol.com]

  • Common Variable Immunodeficiency 11

    […] to infections, autoimmune diseases, hematologic malignancy, or death caused by infection in other family members should increase the provider’s index of suspicion for CVID[mdedge.com] This initial presentation is followed by recurrent febrile episodes with splenomegaly and sometimes hematologic disturbances, arthralgias, or myalgias.[mendelian.co] […] malignant diseases. 15 Although the majority of CVID cases occur sporadically, family history is helpful in securing the correct diagnosis. 15 Known immunodeficiency, unusual susceptibility[mdedge.com]

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