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73 Possible Causes for Arthralgia, Virus Associated Hemophagocytic Syndrome

  • Erythema Infectiosum

    Leg pain and arthralgia occurred in five of the children.[ncbi.nlm.nih.gov] Virus-associated hemophagocytic syndrome.[cmr.asm.org] A 9-year-old child presented with moderate to high grade fever, mild anemia, and erythematous rash involving face, trunks and limbs associated with arthralgia, myalgia and[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    If a person has sickle cell disease, it is present at birth. But most infants do not have any problems from the disease until they are about 5 or 6 months of age. Every state in the United States, the District of Columbia, and the U.S. territories require that all newborn babies receive screening for sickle cell[…][nhlbi.nih.gov]

  • Chronic Active Hepatitis

    In addition, these patients may have arthralgia, oligomenorrhea, fluctuating jaundice and cushingoid appearance with striae, hirsutism and acne.[hepatitiscentral.com] Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] There may also be non-specific symptoms like fatigue, malaise, nausea, abdominal discomfort, itching, and arthralgia’s particularly in the small joints. B.[clinicaladvisor.com]

  • Drug Hypersensitivity

    Diagnosis of AIN should be considered in any case of rapidly progressive renal failure occurring during drug therapy, especially when fever, skin rash, arthralgias, macroscopic[ncbi.nlm.nih.gov] […] of Epstein-Barr Virus and/or Cytomegalovirus Leading to Hemophagocytic Syndrome in One of Two Patients, Annals of Dermatology, 30, 1, (71), (2018).[doi.org] Some distinct clinical syndromes exist: Serum sickness: This reaction typically occurs 7 to 10 days after exposure and causes fever, arthralgias, and rash.[msdmanuals.com]

  • Hepatosplenomegaly

    […] infectious and parasitic Diseases, usually do not cause difficulty in diagnosis, as they are accompanied by characteristic history, marked symptoms of intoxication, fever, arthralgia[authorstream.com] T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol. 1991; 97 :189–194. [ PubMed ] 16.[ncbi.nlm.nih.gov] Craig F, Clare N, Sklar J, Banks P (1991) T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol 97: 189–194. View Article Google Scholar 16.[journals.plos.org]

  • Autoimmune Hepatitis

    At the time of diagnosis of AIH, patients presented with arthralgia, abdominal complaints, cutaneous involvement and fatigue as common symptoms.[ncbi.nlm.nih.gov] Virus-, drug- and lymphoma-associated hemophagocytic syndrome (HPS) was ruled out. Therefore, the patient was diagnosed with autoimmune-associated HPS (AAHS).[ncbi.nlm.nih.gov] Although patients may present with acute symptoms (eg, arthralgia), about 34% to 45% are asymptomatic and are identified subsequent to abnormal liver function tests such as[questdiagnostics.com]

  • Erythema Multiforme

    Systemic side effects of PCV13 include chills, fever, headache, vomiting, fatigue, arthralgia, myalgias, decreased appetite, and diarrhea, whereas its cutaneous adverse reactions[ncbi.nlm.nih.gov] Matsumoto YNaniwa DBanno SSugiura Y The efficacy of therapeutic plasmapheresis for the treatment of fatal hemophagocytic syndrome: two case reports.[jamanetwork.com] […] of hands and feet first spreads proximally and can affect the entire body , including palms and soles Mucus membrane involvement Further symptoms : fever , myalgia , and arthralgia[amboss.com]

  • Viral Pneumonia

    Virus-associated hemophagocytic syndrome may play an important role in development of multiorgan failure and ensuing death in H1N1 infection. [28] For more information on[emedicine.com] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care. 2011 Mar 2. 15(2):R80. [Medline].[emedicine.medscape.com] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care . 2011 Mar 2. 15(2):R80.[emedicine.medscape.com]

  • Precursor-Cell Lymphoblastic Leukemia

    Bone pain, arthralgia, and/or arthritis may manifest as decreased activity, general fussiness, irritability, or refusal to walk.[clinicaladvisor.com] Late-onset fatal Epstein-Barr virusassociated hemophagocytic syndrome following cord blood cell transplantation for adult acute lymphoblastic leukemia .[ajcp.oxfordjournals.org] Epstein-Barr virus associated hemophagocytic lymphohystiocytosis during maintenance treatment of acute lymphoblastic leukemia .[ajcp.oxfordjournals.org]

  • Severe Aplastic Anemia

    Serum sickness, characterized by fever, skin rash, arthralgia, and serpentinous lesions on palms and soles, was observed in two patients (8%) and resolved with administration[scielo.br] In virus-associated hemophagocytic syndrome with an acute parvovirus B19 infection, raised levels of cytokines such as interferon γ would impair regulation of the phagocytic[omicsonline.org]

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