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126 Possible Causes for arylamines

  • Malignant Neoplasm

    […] mutagenesis or tumorigenesis induced by vinyl carbamate and N-nitrosodimethylamine; aflatoxin B1-induced and N-nitrosodiethylamine-induced liver preneoplastic foci in rats; arylamine[doi.org]

  • Sulfonamide

    […] that lack the arylamine group, and may therefore safely take non-arylamine sulfonamides.[en.wikipedia.org] ., an N-containing ring attached to the N1 nitrogen of the sulfonamide group and an arylamine group at the N4 position), and only two agents (amprenavir and fosamprenavir)[ncbi.nlm.nih.gov] The sulfonamides were all classified according to the presence or absence of the N1 substituent and the N4 arylamine.[ajhp.org]

  • Sulfasalazine

    Arylamine N-acetyltransferase 1 NAT1*14A Not Available G A T A C A ADR Inferred Increased risk of Sulfapyridine dose related adverse effects, including skin rash.[drugbank.ca] METHODS: Arylamine N-acetyltransferase 1 (NAT1) and arylamine N-acetyltransferase 2 (NAT2) genotypes were determined in 266 AS patients who received SSZ treatment and 280[ncbi.nlm.nih.gov] Details Arylamine N-acetyltransferase 1 NAT1*14B Not Available G A ADR Inferred Increased risk of Sulfapyridine dose related adverse effects, including skin rash.[drugbank.ca]

  • Carcinoma of Bladder

    […] factors cyclophosphamide (a chemotherapy agent) increases the risk of bladder transitional cell carcinoma with a dose-response pattern 8 aromatic amines in tobacco smoke arylamines[radiopaedia.org] Arylamines exposure used to be very high in Dye, Rubber, Aluminum, Leather industry workers along with truck drivers and pesticide applicators but most arylamines usage has[disabled-world.com] An environmental risk is presented by a class of organic chemicals called arylamines .[britannica.com]

  • Aminoglutethimide

    Previous studies have shown that arylamine metabolism by MPO results in protein radical formation.[ncbi.nlm.nih.gov] Siraki Canadian Journal of Physiology and Pharmacology 2013 91 (3), 228-235 Free Radical Metabolites in Arylamine Toxicity Arno G.[doi.org] HL-60 cells contain abundant amounts of myeloperoxidase (MPO), a hemoprotein, which catalyzes one-electron oxidation of arylamines using H2O2 as a cofactor.[ncbi.nlm.nih.gov]

  • Mycobacterium Smegmatis

    Arylamine N-acetyltransferase is an enzyme that is conserved in most Mycobacterium spp.[ncbi.nlm.nih.gov] Abstract MSMEG_0307 is annotated as a transcriptional regulator belonging to the AraC protein family and is located adjacent to the arylamine N-acetyltransferase (nat) gene[ncbi.nlm.nih.gov]

  • Toxic Oil Syndrome

    Genotype analyses were performed to assess the metabolic capacity of phase I [cytochrome P450 1A1 (CYP1A1), CYP2D6] and phase II [arylamine N-acetyltransferase-2 (NAT2), GSTM1[ncbi.nlm.nih.gov] Abstract The most basic arylamine, aniline, belongs to a class of compounds notorious for inducing allergic and autoimmune reactions.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm of Urinary Bladder

    […] agents in hair dyes might be arylamines ( 9 , 10 ) .[dx.doi.org] To assess arylamine exposure, levels of arylamine–hemoglobin adducts of nine selected alkylanilines (2,3-dimethylaniline [2,3-DMA], 2,4-DMA, 2,5-DMA, 2,6-DMA, 3,4-DMA, 3,5[dx.doi.org] Non-smoking related arylamine exposure and bladder cancer risk.[dx.doi.org]

  • Bladder Neoplasm

    .  Glutathione-S-transferase (GSTM1) conjugates several reactive chemicals, including arylamines and nitrosamines.  The null GSTM1 polymorphism is associated with an increased[slideshare.net] […] factors cyclophosphamide (a chemotherapy agent) increases the risk of bladder transitional cell carcinoma with a dose-response pattern 8 aromatic amines in tobacco smoke arylamines[radiopaedia.org] Benzene and various arylamines are high on the list.[health.harvard.edu]

  • Isoniazid

    Details Arylamine N-acetyltransferase 1 NAT1*14B Not Available G A ADR Inferred Increased risk of toxic reactions.[drugbank.ca] Table 1 Pharmacokinetic assessment at 1 month after initiation of antituberculosis treatment, according to arylamine N -acetyltransferase 2 ( NAT2 ) genotype.[dx.doi.org] Details Arylamine N-acetyltransferase 1 NAT1*15 Not Available C T ADR Inferred Increased risk of toxic reactions.[drugbank.ca]

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