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30 Possible Causes for Ascending Numbness and Weakness

  • Neurosarcoidosis

    A subacute radiculoneuropathy resembling Guillain Barré syndrome has also been noted, in which patients develop an ascending numbness and weakness which can sometimes become[royalfree.nhs.uk]

  • Hereditary ATTR Amyloidosis

    History The subtype of transthyretin (TTR) protein mutation, its tissue distribution, and the amount of amyloid deposition largely determine the clinical manifestations of TTR-related amyloidosis (ATTR). The key characteristic of ATTR that should raise clinical suspicion for this disorder remains the reliable[…][emedicine.medscape.com]

  • TTR Amyloidosis with Polyneuropathy

    Living with a rare disease can be challenging, both physically and emotionally. Please know that we are here to help guide you, your loved ones, and your family members who may be affected by Transthyretin Familial Amyloid Polyneuropathy (TTR-FAP). TTR-FAP is a rare, hereditary, and progressive neurologic disease[…][ttr-fapconnection.com]

  • Transverse Myelitis

    A 56-year-old man was admitted to the hospital reporting 5 months of progressive ascending lower extremity weakness and numbness, inability to walk, bowel incontinence,urinary[ncbi.nlm.nih.gov]

  • Cytomegalovirus

    A 56-year-old man was admitted to the hospital reporting 5 months of progressive ascending lower extremity weakness and numbness, inability to walk, bowel incontinence,urinary[ncbi.nlm.nih.gov]

  • Myelopathy

    […] lower limb weakness.[ncbi.nlm.nih.gov] A 60-year-old man, without any gastrointestinal symptoms, developed over the course of one week rapidly progressive gait imbalance, tingling and numbness in his feet and ascending[ncbi.nlm.nih.gov]

  • Celiac Disease

    […] lower limb weakness.[ncbi.nlm.nih.gov] A 60-year-old man, without any gastrointestinal symptoms, developed over the course of one week rapidly progressive gait imbalance, tingling and numbness in his feet and ascending[ncbi.nlm.nih.gov]

  • Derangement of the Lower Back

    Cauda equina syndrome, a rare complication of spinal stenosis in which ascending numbness or weakness and bladder or bowel incontinence results from extreme pressure on descending[sciatica.org]

  • Subacute Transverse Myelitis

    A 56-year-old man was admitted to the hospital reporting 5 months of progressive ascending lower extremity weakness and numbness, inability to walk, bowel incontinence,urinary[medicinebyalexandrosgsfakianakisblog.wordpress.com] BACKGROUND: A 74-year-old man presented with rapid onset of weakness, numbness, and tingling in his legs, with symptoms ascending to his hands and forearms within days.[lymeneteurope.org]

  • Polyneuropathy

    Symptoms Tingling Numbness Loss of sensation in the arms and legs Symmetrical weakness that usually affects the lower limbs first, and rapidly progresses in an ascending fashion[powerofpain.org] Patients generally notice weakness in their legs, manifesting as “rubbery legs” or legs that tend to buckle, with or without dysesthesias (numbness or tingling).[powerofpain.org]

Further symptoms