Create issue ticket

11 Possible Causes for Ascending Numbness and Weakness, Paresthesia of the Upper Extremity

  • Hereditary ATTR Amyloidosis

    Patisiran is an investigational RNA interference (RNAi) therapeutic in development for the treatment of hereditary ATTR (hATTR) amyloidosis, a progressive disease associated with significant disability, morbidity, and mortality. Here we describe the rationale and design of the Phase 3 APOLLO study, a randomized,[…][ncbi.nlm.nih.gov]

  • Myelopathy

    […] lower limb weakness.[ncbi.nlm.nih.gov] Other symptoms of cervical spondylotic myelopathy include: Pain in the neck, subscapular area, or shoulder Numbness or paresthesia in the upper extremities Sensory changes[emoryhealthcare.org] […] in the upper extremities.[spineuniverse.com]

  • Guillain-Barré Syndrome

    It’s also called: Acute Inflammatory Demyelinating Polyneuropathy Landry’s Ascending Paralysis GBS is characterized by the rapid onset of numbness , weakness, and often paralysis[gbs-cidp.org] CASE REPORT A 54-year-old man presented with lower left facial palsy and paresthesia of his extremities, following an upper respiratory tract infection.[ncbi.nlm.nih.gov] The generally accepted criteria for the diagnosis of Guillain–Barré syndrome include: progressive, ascending weakness of more than two extremities, areflexia and numbness[symptoma.com]

  • Neurosarcoidosis

    A subacute radiculoneuropathy resembling Guillain Barré syndrome has also been noted, in which patients develop an ascending numbness and weakness which can sometimes become[royalfree.nhs.uk] During this presentation, the patient experienced right leg paresthesias, slurred speech, right facial droop, and right upper and lower extremity weakness 2 hours after the[ajnr.org]

  • Decompression Sickness

    weakness or paralysis; girdling abdominal or chest pain.[avweb.com] extremities.[ncbi.nlm.nih.gov] weakness or paralysis in the legs Urinary incontinence and fecal incontinence Girdling (also referred to as girdle, banding, or tightening feeling) around the abdominal region[en.wikipedia.org]

  • Subacute Transverse Myelitis

    A 56-year-old man was admitted to the hospital reporting 5 months of progressive ascending lower extremity weakness and numbness, inability to walk, bowel incontinence,urinary[medicinebyalexandrosgsfakianakisblog.wordpress.com] Six patients (40%) had symmetric sensory and motor dysfunction of their upper or lower extremities and bladder dysfunction, thereby meeting the criteria for ATM during their[jamanetwork.com] BACKGROUND: A 74-year-old man presented with rapid onset of weakness, numbness, and tingling in his legs, with symptoms ascending to his hands and forearms within days.[lymeneteurope.org]

  • Polyneuropathy

    Symptoms Tingling Numbness Loss of sensation in the arms and legs Symmetrical weakness that usually affects the lower limbs first, and rapidly progresses in an ascending fashion[powerofpain.org] Deep tendon reflexes were absent in the upper and lower extremities.[bmcneurol.biomedcentral.com] extremities.[clevelandclinicmeded.com]

  • Cervical Cord Compression

    Pain in the upper extremity, particularly the shoulder, either described as stabbing or dull can appear along with hand numbness.[symptoma.com] Clonus of the upper or lower extremities may be present as well. A positive babinski sign suggests advanced disease.[ispub.com] When these do arise, the most common are neck pain and manifestations of radiculopathy (nerve root irritation or compression resulting in upper extremity symptoms) or myelopathy[americannursetoday.com]

  • Diabetic Pseudotabes

    […] poorly myelinated; primarily sensory and autonomic; symptoms include burning, tingling, numbness, pain heavily myelinated; primarily motor and sensory; symptoms include weakness[quizlet.com] When the ascent reaches the upper tibia, the hands begin to become involved.[mitchmedical.us] , vibratory and position sense loss, numbness, areflexia Acute idiopathic inflammatory polyneuropathy Primarily demyelinating motor polyneuropathy Ascending paralysis( IMPORTANT[quizlet.com]

  • Spinal Demyelination

    As the condition progresses, there can be sensory change, as well (usually numbness and tingling), but the picture is usually dominated by flaccid weakness.[dartmouth.edu] At that time she had spastic upper extremities diparesis, more pronounced in the left arm, and spastic paraplegia, with brisk deep tendon reflexes and bilateral positive Babinski[bmcneurol.biomedcentral.com] Although the most common presentation is with an ascending paralysis, rarely, it can begin by affecting cranial muscles.[dartmouth.edu]

Further symptoms