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335 Possible Causes for Ascites, Hemolysis, Pancytopenia

  • Paroxysmal Nocturnal Hemoglobinuria

    Here we have tested our eculizumab-treated PNH patients (n 12) for signs of hemolysis and assessed complement biomarkers.[] A PVS is a treatment option for ascites due to BCS.[] We report a 19-year-old female patient admitted to the hospital with pancytopenia. Workout of pancytopenia disclosed paroxysmal nocturnal hemoglobinuria.[]

  • Primary Myelofibrosis

    , 222,223,268 which rarely has been the presenting finding of the disease. 224 Occasional patients have a positive acid hemolysis and sucrose hemolysis test, reflecting a[] Here we report a rare case of PMF with anemia, small bowel obstruction and ascites due to extramedullary hematopoiesis and portal hypertension.[] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[]

  • Multicentric Castleman's Disease

    Intravascular Hemolysis Traumatic Hemolysis E. Immunologic Destruction Autoimmune Hemolytic Anemia (AIHA) F.[] We herein describe an unusual case of multicentric Castleman's disease accompanied by thrombocytopenia, ascites, renal failure and myelofibrosis in a Japanese woman.[] Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present.[]

  • Wilson Disease

    In pregnant patients with unrecognized WD, liver failure with hemolysis may be interpreted as the low platelet count (HELLP) syndrome.[] For patients presenting with ascites, diuretics are the treatment of choice.[] Relevant side effects recorded while under treatment with d ‐penicillamine, such as nephrotoxicity, polyneuropathy, pancytopenia, polymyositis and optic neuritis, were not[]

  • Systemic Mastocytosis

    Pre- and post-transfusion urine samples were negative for hemolysis.[] Patient evolved with progressive tension ascites and worsening anemia (6.3 gm/dl) requiring PRBC transfusions.[] The disease progressed rapidly and severe pancytopenia and recurrent upper gastrointestinal bleeding became the dominant problem.[]

  • Leukoerythroblastic Anemia

    The two patients had brisk intravascular hemolysis with direct Coombs' tests positive for complement and with peripheral blood smears showing spherocytosis, erythrophagocytosis[] […] pernicious anemia, leukem … ia, and various cachexias, or it may be due to the accumulation of a large quantity of blood in the peritoneal cavity following the removal of ascitic[] Myeloproliferative Disease, Autosomal Recessive Myeloproliferative Disorder, Chronic, with Eosinophilia myeloproliferative neoplasm neonatal anemia normocytic anemia pancytopenia[]

  • Hemoglobinuria

    2015 ICD-9-CM Diagnosis Code 283.2 Hemoglobinuria due to hemolysis from external causes 2015 Billable Thru Sept 30/2015 Non-Billable On/After Oct 1/2015 ICD-9-CM 283.2 is[] Depending on their localization, thromboses (which affect 30-40 % of untreated patients) may manifest as abdominal pain, hepatomegaly, ascites and headaches.[] In patients with PNH, the absence of CD55 and CD59 results in complement-mediated hemolysis, thrombosis, and pancytopenia.[]

  • Liver Cirrhosis

    Isolated elevation of unconjugated bilirubin level Consider Gilbert syndrome or hemolysis.[] The serum-ascites albumin gradient value of 1.9 g/dL and the total protein level in the ascites of 3.1 g/dL indicated the ascites to have been caused by portal hypertension[] The lymphoma was incidentally found in an enlarged spleen resected palliatively to alleviate symptomatic pancytopenia of the patient.[]

  • Pancytopenia

    Pancytopenia and hemolysis are less frequently observed in vitamin B12 deficiency.[] We report a case of severe CMV hepatitis in an immunocompetent patient presenting with cholestasis, portal hypertension-related ascites and pancytopenia.[] Pancytopenia can be idiopathic or secondary.[]

  • Liver Failure

    Abstract Hepatic infarction is an extremely rare and fatal complication associated with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome.[] After admission, although several major symptoms, including diarrhea, ascites, hyponatremia, and hypoproteinemia, were greatly improved through appropriate treatments, his[] Extrahepatic manifestations include pancytopenia[ 8 ], pancreatitis[ 9, 10 ], and acute renal failure[ 7, 8 ].[]

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