Aspartate Aminotransferase Increased: Causes & Reasons

Possible Causes for Aspartate Aminotransferase Increased

The patient developed the following symptoms/conditions: aspartate aminotransferase increased, musculoskeletal pain ,decreased appetite,prophylaxis,abdominal pain upper,hepatitis [patientsville.com]

aminotransferase (AST) increase) in order to facilitate the selection of patients who might benefit from repeated TACE treatment. 83, 84 The authors reported that even discrete [esmoopen.bmj.com]

The Assessment for Retreatment with TACE (ART) score was developed based on radiological tumour response and impairment of liver function (Child-Pugh score and serum aspartate [esmoopen.bmj.com]

Cholestasis

RESULTS: After BDL, plasma levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), and total bile acids (TBA) were increased and [ncbi.nlm.nih.gov]

Rats treated with 30 mg/kg/day ANIT for 3 weeks exhibited a time-dependent increase in plasma alanine aminotransferase (ALT), aspartate aminotransferase (AST) and bilirubin [ncbi.nlm.nih.gov]

Laboratory findings show increased fasting total serum bile salts (>10 μmol/L) and mild abnormalities of aminotransaminases, with alanine aminotransferase (ALT) and aspartate [worldgastroenterology.org]

Primary Biliary Cirrhosis

In the outpatient clinic, when the aspartate and alanine aminotransferase level exceeded the upper limit of the normal range, the dose of methylprednisolone was increased [ncbi.nlm.nih.gov]

Aspartate, alanine aminotransferase, and bilirubin values were normal. [care.diabetesjournals.org]

[…] alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels Increased lipid and cholesterol levels, with an increased HDL fraction Increased erythrocyte sedimentation [emedicine.medscape.com]

Chronic Alcoholism

Increased serum globulin levels Metabolic Elevated blood ammonia level Hyperglycemia Respiratory alkalosis Hypomagnesemia Hypophosphatemia Hyponatremia Hypokalemia Back to [clevelandclinicmeded.com]

aminotransferase (AST) and alanine aminotransferase (ALT) levels elevated, usually < 300 U/L; AST/ALT ratio ~ 2:1 Hematologic Anemia Leukocytosis or leukopenia Thrombocytopenia [clevelandclinicmeded.com]

Asterixis Confusion, stupor Laboratory Findings Liver synthetic function Hyperbilirubinemia (usually conjugated) Prolonged prothrombin time Hypoalbuminemia Liver enzyme levels Aspartate [clevelandclinicmeded.com]

Hepatocellular Carcinoma

The most commonly reported adverse events included aspartate aminotransferase increase (19%); rash (17%); elevation of alanine aminotransferase (15%), lipase (17%) and amylase [healio.com]

Also the aspartate aminotransferease, alanine aminotransferase and gamma-glutamyltransferase levels were drastically increased. [jbiomeds.com]

The most common grade 3 or grade 4 adverse events included aspartate aminotransferase increase (11%), alanine aminotransferase increase (9%) and lipase increase (9%). [healio.com]

Liver Cirrhosis

Reference range: 4 to 43IU/L AST (GOT) This test detects the presence of the enzyme aspartate aminotransferase in the bloodstream. [otsuka.co.jp]

[…] enzyme related to the bile ducts; often increased if ducts are blocked Aspartate aminotransferase (AST) – an enzyme found in the liver and a few other places, particularly [labtestsonline.org]

This enzyme is also usually only found in the liver, so an increased amount in the bloodstream indicates liver damage. [otsuka.co.jp]

Myocardial Infarction

Enzymes such as glutamine oxaloacetic transaminase (aspartate aminotransferase) and lactate dehydrogenase are still being used for diagnosis of MI in some laboratories. [dx.doi.org]

Raised troponin levels are associated with increased risks of death and recurrent MI. [dx.doi.org]

Cholangitis

[…] slightly, such as aspartate aminotransferase (AST) at106 IU/L, alanine aminotransferase (ALT) at 76 IU/L and albumin was 24g/L. [omicsonline.org]

[…] cholestatic picture with elevated Alkaline Phospatase (ALP) at 176 IU/L, γ-Glutamyl Transpeptidase (γ-GT) at137 IU/L and bilirubin at 32 µmol/L, but the synthetic liver function increased [omicsonline.org]

Viral Hepatitis

Laboratory analyses reveal increased amounts of aspartate aminotransferase (AST) and bilirubin and an abnormal coagulation of the blood. [medical-dictionary.thefreedictionary.com]

Serum ALT is usually increased more than serum aspartate aminotransferase. [academic.oup.com]

The most striking laboratory findings include increases of serum aminotransferase activities, serum bilirubin (both total and direct), and serum alkaline phosphatase activity [academic.oup.com]

Wolman Disease

While alanine aminotransferase levels did not change by week 48, median aspartate aminotransferase levels decreased from 99.5 U/L by 35.3% in six patients. [healio.com]

Regarding liver enzymes, we can observe that patients 1 to 4 had moderately increased aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase, and [hindawi.com]

Additionally, LDL decreased in two patients from 118.8 mg/dL at baseline by a median 47.5% at 48 weeks and HDL increased in three other patients from 9.4 mg/dL at baseline [healio.com]

Cytomegalovirus Infection

Liver function test abnormalities are characterized by mild transaminitis with increases in aspartate aminotransferase, alanine aminotransferase and lactate dehydrogenase, [karger.com]

Erythropoietic Protoporphyria

One or more of these was increased in 17 (25%) patients; sFn correlated with γ-glutamyl transpeptidase (r s = 0.507; P < .001) and alanine aminotransferase (r s = 0.392; P [bloodjournal.org]

< .001) but not with aspartate aminotransferase. [bloodjournal.org]

Pompe Disease

Serum enzymes such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), or lactate dehydrogenase (LDH) may be elevated and may reflect enzymes released from [dx.doi.org]

[…] muscle. 24 There is increasing evidence of the value of a specific glucose tetrasaccharide in urine [Glc 4 (Glcα1-6Glcα1-4Glcα1-4Glc)] in the evaluation of Pompe disease. [dx.doi.org]

Chronic Hepatitis

DIAGNOSIS OF TOXIC HEPATITIS Laboratory Liver damage can be of two types: hepatocellular damage (death of liver cells), in which alanine aminotransferase and aspartate aminotransferase [doi.org]

The control of HBV DNA was associated with a modest, intermittent increase in levels of serum aspartate aminotransferase and alanine aminotransferase that may indicate hepatocyte [doi.org]

The treatment efficacy is measured either by the fall in viraemia (level of HDV RNA) or the normalisation of alanine aminotransferase (ALT) or aspartate aminotransferase [doi.org]

Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

As shown in Table 1, the patient presented with severe hyperammonemia, increased serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), metabolic [frontiersin.org]

Analysis of amino acids in serum revealed increased levels of glutamine. Furthermore, urine analysis revealed strikingly increased orotic acid excretion. [frontiersin.org]

Q Fever

The liver transaminases were mildly increased (alanine aminotransferase, 184 IU/L [41 IU/L, upper limit of normal]; aspartate aminotransferase [AST], 161 IU/L [42 IU/L, upper [academic.oup.com]

The erythrocyte sedimentation rate (ESR) was normal at 5 mm/h; however, his C-reactive protein was mildly increased to 18.5 mg/L (8 mg/L, limit of normal). [academic.oup.com]

Histoplasmosis

At this time, there was a substantial drop in the hemoglobin level (from 7.8 to 4.6 g per deciliter), an increase in the aspartate aminotransferase level (to 626 U per liter [doi.org]

COVID-19

Features | Politics | East Asia There are plenty of differences between Gorbachev’s Soviet Union and Xi’s China. But there are enough similarities that Xi should be worried. A member of a Chinese honor guard wears a face mask as he stands guard on Tiananmen Square in Beijing, Feb. 4, 2020. Credit: AP Photo/Mark[…] [thediplomat.com]

Infectious Mononucleosis

Characterized by the classic triad of fever, pharyngitis, and lymphadenopathy, along with atypical lymphocytosis. Often subclinical in young children. Positive heterophile antibody test and serologic test for antibodies against EBV are usually diagnostic. Rare but potentially life-threatening complications include severe[…] [us.bestpractice.bmj.com]

Pulmonary Embolism

A 29-year-old male patient was treated and followed up for a pulmonary embolism. The patient had no relevant medical history, other than the fact that he had smoked bonzai, a synthetic cannabinoid derivative, for 2 years. Hypercoagulability tests were normal. The use of synthetic cannabinoids is increasing in the[…] [ncbi.nlm.nih.gov]

Liver Metastasis

BACKGROUND: Optimal surgical management for patients with synchronous colorectal cancer liver metastasis is controversial. We provide an analysis of surgical utilization and outcomes for patients presenting with synchronous colon and rectal cancer liver metastasis between simultaneous and staged approaches.[…] [ncbi.nlm.nih.gov]

Cholecystitis

ACUTE CALCULOUS CHOLECYSTITIS Sonographic Examination of Gallbladder: The gallbladder is generally imaged with patients in both supine and posterior oblique (LPO) positions. Upright and, on occasion, prone scans may be helpful to visualize very small gallstones. When stones are not immediately apparent, the region of[…] [ultrasoundtraining.com]

Angiomyolipoma

Epithelioid angiomyolipoma (EAML) is a subtype of angiomyolipoma with malignant potential. A diagnosis of malignant EAML of the kidney is based on extrarenal metastasis, and predicting early transformation is difficult. To propose criteria for indicators of malignant transformation, herein we report 2 cases and review[…] [ncbi.nlm.nih.gov]

Myositis

Semin Neurol. Author manuscript; available in PMC 2013 Nov 1. Published in final edited form as: PMCID: PMC3535450 NIHMSID: NIHMS429507 The publisher's final edited version of this article is available at Semin Neurol See other articles in PMC that cite the published article. Abstract The idiopathic inflammatory myopathies[…] [ncbi.nlm.nih.gov]

Myocarditis

BMC Res Notes. 2018 Mar 9;11(1):168. doi: 10.1186/s13104-018-3273-1. Author information 1 Department of Medicine, University of Peradeniiya, Peradeniya, Sri Lanka. udayapralapanawa@yahoo.com. 2 University Medical Unit, Teaching Hospital Peradeniya, Peradeniya, Sri Lanka. 3 Department of Medicine, University of Peradeniiya,[…] [ncbi.nlm.nih.gov]

Gaucher Disease

Gaucher's disease Acid beta-glucosidase Specialty Endocrinology Gaucher's disease or Gaucher disease () (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs. The disorder is characterized by bruising, fatigue, anemia, low blood[…] [en.wikipedia.org]

Aggressive Systemic Mastocytosis

Summary Epidemiology It represents less than 10% of cases of SM and the global prevalence is estimated in the order of between 1/400,000 and 1/250,000. Clinical description ASM doesn't usually develop in children. Cutaneous involvement is normally absent. Patients present with severe symptoms related to mast cell[…] [orpha.net]

Disseminated Histoplasmosis

We describe an unusual clinical association of disseminated histoplasmosis with reactive hemophagocytic syndrome. We report the case of a new HIV-positive patient with reconstitution inflammatory syndrome like reactive hemophagocytic syndrome associated with disseminated histoplasmosis. We describe the clinical case,[…] [ncbi.nlm.nih.gov]

Arteriosclerotic Retinopathy

Alanine Aminotransferase Increased, Arteriosclerotic Retinopathy, Aspartate Aminotransferase Increased, Blood Albumin Decreased, Blood Creatine Increased, Blood Glucose Increased [patientsville.com]

When starting to take Cdp870 the consumer reported the following symptoms: Alanine Aminotransferase Increased Arteriosclerotic Retinopathy Aspartate Aminotransferase Increased [patientsville.com]

3Beta-Hydroxy-Delta5-C27-Steroid Oxidoreductase Deficiency

From Wikipedia, the free encyclopedia 3-β-HSD (or 3-β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase ) is an enzyme which catalyses the synthesis of progesterone from pregnenolone, 17-hydroxyprogesterone from 17-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone in the adrenal gland. It is the[…] [dictionnaire.sensagent.leparisien.fr]