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2,320 Possible Causes for Aspartate Transaminase Increased, Glucose Decreased, Liver Biopsy showing Periportal Necrosis

  • Viral Hepatitis

    Also, HBV DNA levels are increased. Additionally, alanine transaminase (ALT) and aspartate transaminase (AST) levels are consistently or intermittently elevated.[symptoma.com] […] diabetes Avoiding alcohol Some studies suggest that drugs that decrease insulin resistance may be helpful.[labtestsonline.org] There are some things that can be done that often lead to improvement in the condition of the liver: Weight loss in those who are obese Good glucose control in those who have[labtestsonline.org]

  • Primary Biliary Cirrhosis

    Liver biopsy showed lymphocytic and plasmacytic infiltration in the portal and periportal areas, with numerous areas of bridging centrilobular necrosis, indicating AIH.[ncbi.nlm.nih.gov] Liver function test showed alanine transaminase to be in the normal range, but aspartate transaminase showed a discrete increase (57.0 U/l; reference: Due to negative results[karger.com] The decreased plasma glucose clearance in the same mouse model was further investigated to determine whether the decreased plasma glucose clearance resulted from impaired[doi.org]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Liver Function Tests ASPARTATE TRANSAMINASE (AST) Serum Glutamic Oxaloacetic Transaminase (SGOT) or aspartate aminotransaminase Mitochondrial Also associated with liver parenchymal[slideshare.net] FIGURE 2 Massive hepatic necrosis, and ductular cells from postoperative day (POD) 0 to POD 7 after auxiliary partial orthotopic liver transplantation.[nature.com]

  • Chronic Alcoholism

    Thus, ethanol consumption increases blood lactate concentration, while decreasing the level of glucose.[pubs.sciepub.com] Also check fasting glucose, as chronic pancreatitis can lead to diabetes mellitus.[patient.info] For example, folate deficiency alters the cells lining the small intestine, which in turn impairs absorption of water and nutrients, including glucose and sodium.[crchealth.com]

    Missing: Liver Biopsy showing Periportal Necrosis
  • Hepatocellular Carcinoma

    Rarely, hemoperitoneum in a cirrhotic patient may shine the light on HCC after a sudden increase in alkaline phosphatase and aspartate transaminase/alanine transaminase levels[docksci.com] Larocca and Cristián Favre, Metformin and glucose starvation decrease the migratory ability of hepatocellular carcinoma cells: targeting AMPK activation to control migration[doi.org]

    Missing: Liver Biopsy showing Periportal Necrosis
  • Liver Metastasis

    Primary retroperitoneal serous adenocarcinoma (PRSA) is a rare malignancy of which only seven cases have been reported in the literature. The clinical features and outcomes of PRSA are not well understood. We herein report a case of PRSA with liver metastasis in a 74-year-old woman who was treated with surgical[…][ncbi.nlm.nih.gov]

    Missing: Liver Biopsy showing Periportal Necrosis
  • Isoniazid Hepatitis

    Abstract Two patients with liver failure secondary to isoniazid hepatotoxicity were successfully treated with orthotopic liver transplantation. A 49-year-old man received isoniazid prophylaxis for a positive tuberculin test, and a 60-year-old woman was treated for active pulmonary tuberculosis with isoniazid, rifampin,[…][ncbi.nlm.nih.gov]

    Missing: Aspartate Transaminase Increased
  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] An increased aspartate transaminase (AST)/alanine transaminase (ALT) ratio is occasionally associated with fibrosis. Ferritin is correlated with hepatic fibrosis.[doi.org] Thus, exercise decreases levels of serum glucose and insulin[ 67 ].[doi.org]

  • Myocardial Infarction

    The level of serum aspartate transaminase (AST) increases rapidly in 4 to 6 hours, reaches its peak in 24 to 48 hours, and returns to normal in five days.[medical-dictionary.thefreedictionary.com] Although the mechanisms underlying this association are not fully understood, evidence that the use of insulin to lower glucose concentrations decreases mortality in diabetic[care.diabetesjournals.org] Enzymes such as glutamine oxaloacetic transaminase (aspartate aminotransferase) and lactate dehydrogenase are still being used for diagnosis of MI in some laboratories.[dx.doi.org]

    Missing: Liver Biopsy showing Periportal Necrosis
  • Liver Cirrhosis

    During liver injury, ALT released from damaged cells can rapidly increase ALT activity in the serum. 11 Aspartate transaminase (AST) is present not only in the liver but also[dx.doi.org] […] that fasting plasma glucose and fasting immunoreactive insulin decreased during interferon treatment ( 72 ).[care.diabetesjournals.org] In the fasting state, glucose is generated in the liver via glycogenolysis and gluconeogenesis; thus, blood glucose levels are maintained[ 30 ].[wjgnet.com]

    Missing: Liver Biopsy showing Periportal Necrosis

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