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20 Possible Causes for Aspiration Pneumonia, Compound Muscle Action Potential with Low Amplitude, Diplopia

  • Myasthenia Gravis

    A46-year male presented with unilateral ptosis and diplopia.[ncbi.nlm.nih.gov] Complications Aspiration pneumonia due to throat muscle weakness. Acute respiratory failure during an exacerbation.[patient.info] Distinguishing features of the RNS test in LEMS and MG are confirmed in this direct comparison study: the low compound muscle action potential amplitude, decrement at LRS,[ncbi.nlm.nih.gov]

  • Guillain-Barré Syndrome

    CASE REPORT: A 76-year-old woman was initially presented with diplopia, ophthalmoplegia, and ataxia, but she later developed weakness of limbs, respiratory failure, deterioration[ncbi.nlm.nih.gov] Thromboembolism, pneumonia, skin breakdown. Cardiac arrhythmia. Ileus. Aspiration pneumonia. Urinary retention. Psychiatric problems - eg, depression, anxiety.[patient.info] muscle action potentials reduced amplitude with relatively preserved conduction velocity implicates axonal neuropathy delayed/absent F waves implicates nerve root involvement[step2.medbullets.com]

  • Lambert Eaton Myasthenic Syndrome

    She recently developed unilateral ptosis and diplopia which dramatically improved with pyridostigmine suggesting concomitant MG.[ncbi.nlm.nih.gov] Approximately 2 months after the operation, he had aspiration pneumonia with respiratory failure.[jmedicalcasereports.biomedcentral.com] Distinguishing features of the RNS test in LEMS and MG are confirmed in this direct comparison study: the low compound muscle action potential amplitude, decrement at LRS,[ncbi.nlm.nih.gov]

  • Miller-Fisher Syndrome

    The immediate cause of death was considered to be aspiration pneumonia.[academic.oup.com] CBs resolved, distal compound muscle action potential (CMAP) amplitudes increased and SNAPs normalized on subsequent testing.[ncbi.nlm.nih.gov] CASE REPORT.: An 81-year-old white man presented with an acute onset of diplopia after a mild gastrointestinal illness.[ncbi.nlm.nih.gov]

  • Dermatomyositis

    Pulmonary manifestations range from aspiration pneumonia to interstitial lung disease (ILD), sometimes with complications such as pulmonary arterial hypertension (see these[orpha.net] Low compound muscle action potentials (CMAP) amplitudes may not necessarily indicate a neuropathic process, as it may reflect muscle atrophy and fibrosis.[doi.org] Ptosis of the eyelids, diplopia, and strabismus due to extraocular muscle involvement can be observed in some DM patients [4].[link.springer.com]

  • Food-Borne Botulism

    Of the 41 botulinal toxin-positive persons, 38 (93%) had at least three of the commonly recognized pentad of signs or symptoms--nausea and vomiting, dysphagia, diplopia, dilated[ncbi.nlm.nih.gov] A higher chance of acquiring aspiration pneumonia, respiratory distress, long-lasting weakness, and nervous system problems for up to a year following the illness is common[microbewiki.kenyon.edu] Electrophysiologic tests of such patients show reduced compound muscle action potentials (CMAPs), low amplitudes and short durations of motor unit potentials (MUPs), and mild[ncbi.nlm.nih.gov]

  • Neuromuscular Junction Disorder

    Lambert- Eaton -- eyes are usually spared myasthenia gravis - symptoms 1. ptosis 2. diplopia 3. weakness worsen with muscle use Lambert- Eaton myasthenic syndrome - symptoms[brainscape.com] Aspiration pneumonia is clearly an undesirable outcome in someone with already compromised respiratory function.[jnnp.bmj.com] EMNG showed signs of myopathy and low compound muscle action potential (CMAP) amplitude (0,15 mV) on lower extremities. Muscle and nerve biopsy were normal.[neurology.org]

  • Inclusion Body Myositis

    Weakness affects most severely muscles that are innervated by brain stem nuclei, such as extraocular and facial muscles, and causes drooping of the eyelids, diplopia, and[neuropathology-web.org] The incidence of dysphagia, rate of aspirations, rate of aspiration pneumonias and treatment results of dysphagia were analyzed.[ncbi.nlm.nih.gov] However, the low compound muscle action potential amplitudes could be explained by the loss of excitable muscle tissue that occurs in myopathies.[jamanetwork.com]

  • Transient Neonatal Myasthenia Gravis

    Motor neuron disease – Ptosis and diplopia are not symptoms of ALS, MG is not progressive, does not show upper or lower motor neuron signs Brainstem tumors – MRI is useful[pedclerk.bsd.uchicago.edu] Additional complications might include food aspiration, choking, or pneumonia.[disabled-world.com] A decremental pattern ( 10% difference in compound muscle action potential amplitude between the first and fourth or fifth stimulus) is the usual finding.[emedicine.medscape.com]

  • Neuropathy

    Disease of CN III, IV, and VI manifests as acute or subacute periorbital pain or headache followed by diplopia.[emedicine.medscape.com] Compounding the problem of aspiration pneumonias and chronic lung disease is the presence of relative insensitivity to hypoxemia [ 23 - 26 ], which limits ability to cope[ncbi.nlm.nih.gov] Patients have relatively normal nerve conduction velocities but low amplitude sensory nerve action potentials and compound muscle action potentials.[merckmanuals.com]

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