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13 Possible Causes for AST/ALT Ratio High, Easy Bruising

  • Alcoholic Liver Disease

    Diagnosis Ratio of AST/ALT 1.5:2 Low albumin High PT High MCV Low platelets Other Tests Ultrasound may be helpful to investigate liver damage.[rcemlearning.co.uk] Symptoms of cirrhosis may include fatigue, bleeding easily, easy bruising, fluid accumulation in the abdomen ( ascites ), loss of appetite, nausea, swelling in the legs (edema[liversupport.com] High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking . Alcohol Alcohol 2004; 39 :336–339. 127. de BG , Graviss EA .[nature.com]

  • Alcoholic Hepatitis

    […] deficiency) Endocrine Gynaecomastia Testicular atrophy Loss of body hair Signs of ‘pseudo- Cushings ’ (red face, hump, striae) Face /skin Parotid enlargement Spider naevi Easy[almostadoctor.co.uk] […] bleeding or bruising The symptoms of alcoholic hepatitis are similar to those caused by other health conditions.[healthline.com] bruising Dupuytren’s contracture Neuromuscular Tremor Memory loss / cognitive impairment Peripheral myopathy- degradation of muscle Epilepsy Wernicke-Korskoff syndrome Cardiovascular[almostadoctor.co.uk]

  • Alcoholic Fatty Liver

    Factors associated with advanced fibrosis in NAFLD were age 40 years, diabetes mellitus, AST/ALT ratio   1 and raised GGT.[ncbi.nlm.nih.gov] bruising, and mental problems (e.g., memory loss).[medbroadcast.com] (p .001) and AST (p .001) levels, improvement in AST/ALT ratio and APRI scores (p .01), and reduction in total bilirubin.[ncbi.nlm.nih.gov]

  • Portal Cirrhosis

    High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking. Alcohol and alcoholism. 2004;39(4):336–9. pmid:15208167.[journals.plos.org] Cirrhosis can lead to Easy bruising or bleeding, or nosebleeds Swelling of the abdomen or legs Extra sensitivity to medicines High blood pressure in the vein entering the[icdlist.com] It is interesting that Lok index, a fibrosis marker based on AST/ALT ratio, PT-INR, and platelet count, was predictive of clinical outcome in patients with alcoholic cirrhosis[journals.plos.org]

  • Pancytopenia

    This, combined with an AST/ALT ratio of less than one, reduced suspicion of alcohol-related liver damage.[tidsskriftet.no] Leukopenia results as frequent, reccurent infections and fever Thrombocytopenia causes easy bruising, nose bleeds, bleeding of gums and unexplained bleeding of the internal[symptoma.com] If a pancytopenia is more severe then the patient may experience mucosal bleeding, easy bruising, purpura and petechiae due to thrombocytopenia.[info.isabelhealthcare.com]

  • Liver Cirrhosis

    However, certain patients including those with reversed ALT-to-AST ratio, hypertriglyceridemia, and thrombocytopenia are at high risk for progressive disease ( 134 , 135 )[care.diabetesjournals.org] There may be also easy bruising. There also may be heavy internal bleeding from the food pipe which may be fatal.[symptoma.com] Kidney disease or failure Easy bruising and severe bleeding. This happens when the liver stops making proteins that are needed for your blood to clot. Type 2 diabetes.[hopkinsmedicine.org]

  • Liver Failure

    However, certain patients including those with reversed ALT-to-AST ratio, hypertriglyceridemia, and thrombocytopenia are at high risk for progressive disease ( 134 , 135 )[care.diabetesjournals.org] Kidney disease or failure Easy bruising and severe bleeding. This happens when the liver stops making proteins that are needed for your blood to clot. Type 2 diabetes.[hopkinsmedicine.org] bruising and abnormal bleeding Confusion or problems thinking Pale or clay-colored stools Your health care provider will do a physical exam to look for: An enlarged liver[medlineplus.gov]

  • Cryptogenic Cirrhosis

    However, certain patients including those with reversed ALT-to-AST ratio, hypertriglyceridemia, and thrombocytopenia are at high risk for progressive disease ( 134 , 135 )[care.diabetesjournals.org] Cirrhosis can lead to Easy bruising or bleeding, or nosebleeds Swelling of the abdomen or legs Extra sensitivity to medicines High blood pressure in the vein entering the[icdlist.com] Cirrhosis can cause weakness , loss of appetite , easy bruising , yellowing of the skin ( jaundice ), itching , and fatigue .[medicinenet.com]

  • Pyridoxine Dependency Syndrome

    ALT ratio in alcoholic hepatitis.[medical-dictionary.thefreedictionary.com] Jonah & Sam were just diagnosed with a bleeding disorder...after all these years without answers in regards to Jonah's frequent and severe bloody noses and easy bruising.[angelfire.com] Reduction of glutamic pyruvic transaminase in pyridoxine deficiency in liver disease. 3) showed that correction of plasma pyridoxine deficiency did not abolish the high AST[medical-dictionary.thefreedictionary.com]

  • Biliary Tract Infection

    High risk factors for increasing CD4 /CD8 ratio were investigated with patients of malignant obstructive jaundice, which includes blood glucose, glycosylated hemoglobin, ALT[alliedacademies.org] Other cholangiocarcinoma symptoms may include weight loss , loss of appetite , weakness , loss of energy, and easy bruising or bleeding (factors that clot the blood are manufactured[medicinenet.com] , AST, LDL-C, HDL-C and triglycerides, hs-CRP, neutrophil count, neutrophil percentage, T lymphocyte count, ratio of CD4 /CD8 and biliary tumor size.[alliedacademies.org]

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