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108 Possible Causes for Asthenia, Confusion, Spasticity - Hyperreflexia

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[] CASE: A 17-year-old boy was admitted to the emergency department with abdominal pain, nausea and vomiting, asthenia, and weight loss.[] Moderate - personality change, muscle cramps and weakness, confusion, ataxia. Severe - drowsiness.[]

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[] […] weeks, and include progressive weakness on one side of the body or clumsiness of limbs, disturbance of vision, and changes in thinking, memory, and orientation leading to confusion[] The confusion may arise because the disease modifying drugs for relapsing remitting MS are not available to people with primary progressive MS.[]

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[] Kennedy’s Disease Kennedy’s Disease and MND have similar traits, which can cause confusion during diagnosis.[] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[]

  • Radiculomyelopathy

    Myelopathic features are characterized by a more abrupt onset and include spastic paraplegia or quadriplegia, hyperreflexia, Babinski reflex, clonus, or a variety of sensory[] Important diagnoses which may cause confusion are listed in the box under 'Differential diagnosis', below.[] […] conduction studies high false negative rate may be useful to distinguish peripheral from central process (ALS) Differential Normal aging mild symptoms of myelopathy often confused[]

  • Hypernatremia

    Muscle twitching, tremor, spasticity, hyperreflexia, and lethargy may also be seen. Coma, seizures, and muscle weakness are later signs.[] […] of hypernatremic patients and risk factors for death occurrence during hospitalization Age (years) 79.7   14 85.3   10.7 77.2   14.7 Male 44% 63% 41% Cause of admission Asthenia[] Confusion, neuromuscular excitability, hyperreflexia, seizures, or coma may result.[]

  • Infantile Neuroaxonal Dystrophy

    Clinical Onset before age three years Psychomotor regression (most common presenting feature) Early truncal hypotonia followed by spastic tetraparesis (usually with hyperreflexia[] NBIA2B has a later onset (4-5 years) and profound sensorimotor impairment but there are many overlapping features and the nosology is confusing.[]

  • Neurosyphilis

    […] paresis and hyperreflexia 7,8 occurs months to years after infection 3,4 meningovascular syphilis prodrome of mild clinical features of syphilitic meningitis 4,9 this is[] The patient reported asthenia (abnormal loss of strength), weight loss, and bilateral red, painful eyes. He also reported severe vision loss, which had been progressive.[] He was found to have positive syphilis serology during a routine confusion screen, and the possibility of neurosyphilis was raised.[]

  • Lower Motor Neuron Syndrome with Late-Adult Onset

    , spasticity -muscle atrophy (fasciculations), fasciculations, tongue atrophy, rapidly progressive (lethal) -upper & lower motor neurons, bulbar weakness -normal sensation[] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[] The confusion in the use of the terminology complicates assessment and treatment planning by health professionals, as many confuse the other findings of upper motor neuron[]

  • Paraneoplastic Neurologic Syndrome

    Given that the index patient presented with hyperreflexia and a positive Babinski reflex, it is of note that mutations in beta-NAP have been proposed to play a role in spastic[] A 49-year-old woman presented with a history of progressive asthenia of the lower extremities persisting for 2 months.[] This case 35MSeizures, confusion, agitation, decreased to no verbal responseGAD, VGKC-complex, AchR (binding), CRMP5Hu, Ri, Yo, VGCC, NMDA, GABA-B, AMPA, ANNA-3, anti-glial[]

  • Muscle Spasticity

    Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS.[] The most commonly reported adverse effects in the tizanidine group were drowsiness, xerostomia (P 0.001) and asthenia (not significant).[] Although basic science descriptions of spasticity are being elucidated, clinically, confusion exists.[]

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