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108 Possible Causes for Asthenia, Confusion, Spasticity - Hyperreflexia

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[aafp.org] CASE: A 17-year-old boy was admitted to the emergency department with abdominal pain, nausea and vomiting, asthenia, and weight loss.[ncbi.nlm.nih.gov] Moderate - personality change, muscle cramps and weakness, confusion, ataxia. Severe - drowsiness.[patient.info]

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[icdlist.com] […] weeks, and include progressive weakness on one side of the body or clumsiness of limbs, disturbance of vision, and changes in thinking, memory, and orientation leading to confusion[ocrevus.com] The confusion may arise because the disease modifying drugs for relapsing remitting MS are not available to people with primary progressive MS.[mstrust.org.uk]

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[en.wikipedia.org] Kennedy’s Disease Kennedy’s Disease and MND have similar traits, which can cause confusion during diagnosis.[imnda.ie] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[symptoma.com]

  • Radiculomyelopathy

    Myelopathic features are characterized by a more abrupt onset and include spastic paraplegia or quadriplegia, hyperreflexia, Babinski reflex, clonus, or a variety of sensory[fluoridealert.org] Important diagnoses which may cause confusion are listed in the box under 'Differential diagnosis', below.[patient.info] […] conduction studies high false negative rate may be useful to distinguish peripheral from central process (ALS) Differential Normal aging mild symptoms of myelopathy often confused[orthobullets.com]

  • Hypernatremia

    Muscle twitching, tremor, spasticity, hyperreflexia, and lethargy may also be seen. Coma, seizures, and muscle weakness are later signs.[aneskey.com] […] of hypernatremic patients and risk factors for death occurrence during hospitalization Age (years) 79.7   14 85.3   10.7 77.2   14.7 Male 44% 63% 41% Cause of admission Asthenia[bmcnephrol.biomedcentral.com] Confusion, neuromuscular excitability, hyperreflexia, seizures, or coma may result.[web.archive.org]

  • Infantile Neuroaxonal Dystrophy

    Clinical Onset before age three years Psychomotor regression (most common presenting feature) Early truncal hypotonia followed by spastic tetraparesis (usually with hyperreflexia[ncbi.nlm.nih.gov] NBIA2B has a later onset (4-5 years) and profound sensorimotor impairment but there are many overlapping features and the nosology is confusing.[disorders.eyes.arizona.edu]

  • Neurosyphilis

    […] paresis and hyperreflexia 7,8 occurs months to years after infection 3,4 meningovascular syphilis prodrome of mild clinical features of syphilitic meningitis 4,9 this is[radiopaedia.org] The patient reported asthenia (abnormal loss of strength), weight loss, and bilateral red, painful eyes. He also reported severe vision loss, which had been progressive.[pharmacytimes.com] He was found to have positive syphilis serology during a routine confusion screen, and the possibility of neurosyphilis was raised.[ncbi.nlm.nih.gov]

  • Lower Motor Neuron Syndrome with Late-Adult Onset

    , spasticity -muscle atrophy (fasciculations), fasciculations, tongue atrophy, rapidly progressive (lethal) -upper & lower motor neurons, bulbar weakness -normal sensation[brainscape.com] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[neuroweb.us] The confusion in the use of the terminology complicates assessment and treatment planning by health professionals, as many confuse the other findings of upper motor neuron[en.wikipedia.org]

  • Paraneoplastic Neurologic Syndrome

    Given that the index patient presented with hyperreflexia and a positive Babinski reflex, it is of note that mutations in beta-NAP have been proposed to play a role in spastic[jneuroinflammation.com] A 49-year-old woman presented with a history of progressive asthenia of the lower extremities persisting for 2 months.[ncbi.nlm.nih.gov] This case 35MSeizures, confusion, agitation, decreased to no verbal responseGAD, VGKC-complex, AchR (binding), CRMP5Hu, Ri, Yo, VGCC, NMDA, GABA-B, AMPA, ANNA-3, anti-glial[nnjournal.net]

  • Muscle Spasticity

    Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS.[profiles.umassmed.edu] The most commonly reported adverse effects in the tizanidine group were drowsiness, xerostomia (P 0.001) and asthenia (not significant).[doi.org] Although basic science descriptions of spasticity are being elucidated, clinically, confusion exists.[ncbi.nlm.nih.gov]

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