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96 Possible Causes for Asthenia, Dementia, Spasticity - Hyperreflexia

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[en.wikipedia.org] Frontotemporal dementia-motor neuron disease is now recognised as an important dementia syndrome, which presents substantial challenges for diagnosis and management.[ncbi.nlm.nih.gov] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[symptoma.com]

  • Infantile Neuroaxonal Dystrophy

    Clinical Onset before age three years Psychomotor regression (most common presenting feature) Early truncal hypotonia followed by spastic tetraparesis (usually with hyperreflexia[ncbi.nlm.nih.gov] […] dystrophy is a rare neurodegenerative disorder characterized by infantile onset and rapid progression of psychomotor regression and hypotonia evolving into spasticity and dementia[ncbi.nlm.nih.gov] […] dystrophy (INAD), showed a gradual deterioration from 16 months; at age 5 years she was bedridden, with severe tetraplegia, strabismus, nystagmus and optic atrophy, and dementia[ncbi.nlm.nih.gov]

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[aafp.org] CASE: A 17-year-old boy was admitted to the emergency department with abdominal pain, nausea and vomiting, asthenia, and weight loss.[ncbi.nlm.nih.gov] Independent of adjusting factors, hyponatremia patients had 2.36-fold higher chances of suffering dementia, including Alzheimer's disease (AD) and non-AD dementia, than the[ncbi.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis

    The upper motor signs include spasticity, hyperreflexia and weakness. The lower motor signs include amyotrophy, weakness and fasciculations.[symptoma.com] Asthenia There was a trend toward more asthenia among the treated participants in each trial, and this became statistically significant when the data from the three trials[doi.org] These syndromes range from frontotemporal dementia to behavioral or cognitive syndromes.[ncbi.nlm.nih.gov]

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[icdlist.com] Here we report a patient with early psychiatric symptoms including depression, dementia, and catatonia, who was eventually diagnosed as having primary progressive multiple[ncbi.nlm.nih.gov] […] due to multiple sclerosis w behavioral disturbance Dementia due to multiple sclerosis with altered behavior Dementia from multiple sclerosis Exacerbation of multiple sclerosis[icd10data.com]

  • Radiculomyelopathy

    Myelopathic features are characterized by a more abrupt onset and include spastic paraplegia or quadriplegia, hyperreflexia, Babinski reflex, clonus, or a variety of sensory[fluoridealert.org] Cognition is also usually spared, although there are forms associated with frontotemporal dementia 5 ; one author found that 15% of patients with frontotemporal lobar dementia[consultant360.com] Cognitive dysfunction may occur and 5-15% of patients develop dementia, usually of frontotemporal type.[patient.info]

  • Lower Motor Neuron Syndrome with Late-Adult Onset

    , spasticity -muscle atrophy (fasciculations), fasciculations, tongue atrophy, rapidly progressive (lethal) -upper & lower motor neurons, bulbar weakness -normal sensation[brainscape.com] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[neuroweb.us] These include criteria for the diagnosis of multiple sclerosis, dementia of Lewy-body type, frontal lobe dementias, chronic fatigue syndrome, and inflammatory neuropathies[books.google.com]

  • Neurosyphilis

    […] paresis and hyperreflexia 7,8 occurs months to years after infection 3,4 meningovascular syphilis prodrome of mild clinical features of syphilitic meningitis 4,9 this is[radiopaedia.org] The patient reported asthenia (abnormal loss of strength), weight loss, and bilateral red, painful eyes. He also reported severe vision loss, which had been progressive.[pharmacytimes.com] Neurosyphilis should not be overlooked as an etiology for progressive dementia even in this post-antibiotic era.[ncbi.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis Type 1

    hyperreflexia ( ) Hoffman's ( ) Babinski's spastic dysarthria lower motor neuron (LMN) signs muscular atrophy weakness clinical fasciculations clumsiness Evaluation Diagnosis[orthobullets.com] […] positive effect on functional abilities from the use of riluzole is unclear, and no studies have reported that the drug halts the disease process. 21 Adverse effects include asthenia[aafp.org] ALS amyotrophic lateral sclerosis with dementia Charcot disease dementia with amyotrophic lateral sclerosis Lou Gehrig disease motor neuron disease, amyotrophic lateral sclerosis[ghr.nlm.nih.gov]

  • Friedreich Ataxia

    His examination was significant for spastic gait, hyperreflexia, and sensory neuropathy. Genetic testing revealed a compound heterozygous mutation in the FXN gene.[ncbi.nlm.nih.gov] Adverse effects One participant in Zannolli 2012 (total of 13 enrolled participants) experienced asthenia during drug tapering, which did not require medical intervention.[doi.org] Program at Tufts Medical Center in Boston to learn more about treating degenerative brain disease and other types of dementia.[tuftsmedicalcenter.org]

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