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96 Possible Causes for Asthenia, Dementia, Spasticity - Hyperreflexia

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[] Frontotemporal dementia-motor neuron disease is now recognised as an important dementia syndrome, which presents substantial challenges for diagnosis and management.[] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[]

  • Infantile Neuroaxonal Dystrophy

    Clinical Onset before age three years Psychomotor regression (most common presenting feature) Early truncal hypotonia followed by spastic tetraparesis (usually with hyperreflexia[] […] dystrophy is a rare neurodegenerative disorder characterized by infantile onset and rapid progression of psychomotor regression and hypotonia evolving into spasticity and dementia[] […] dystrophy (INAD), showed a gradual deterioration from 16 months; at age 5 years she was bedridden, with severe tetraplegia, strabismus, nystagmus and optic atrophy, and dementia[]

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[] CASE: A 17-year-old boy was admitted to the emergency department with abdominal pain, nausea and vomiting, asthenia, and weight loss.[] Independent of adjusting factors, hyponatremia patients had 2.36-fold higher chances of suffering dementia, including Alzheimer's disease (AD) and non-AD dementia, than the[]

  • Amyotrophic Lateral Sclerosis

    The upper motor signs include spasticity, hyperreflexia and weakness. The lower motor signs include amyotrophy, weakness and fasciculations.[] Asthenia There was a trend toward more asthenia among the treated participants in each trial, and this became statistically significant when the data from the three trials[] These syndromes range from frontotemporal dementia to behavioral or cognitive syndromes.[]

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[] Here we report a patient with early psychiatric symptoms including depression, dementia, and catatonia, who was eventually diagnosed as having primary progressive multiple[] […] due to multiple sclerosis w behavioral disturbance Dementia due to multiple sclerosis with altered behavior Dementia from multiple sclerosis Exacerbation of multiple sclerosis[]

  • Radiculomyelopathy

    Myelopathic features are characterized by a more abrupt onset and include spastic paraplegia or quadriplegia, hyperreflexia, Babinski reflex, clonus, or a variety of sensory[] Cognition is also usually spared, although there are forms associated with frontotemporal dementia 5 ; one author found that 15% of patients with frontotemporal lobar dementia[] Cognitive dysfunction may occur and 5-15% of patients develop dementia, usually of frontotemporal type.[]

  • Lower Motor Neuron Syndrome with Late-Adult Onset

    , spasticity -muscle atrophy (fasciculations), fasciculations, tongue atrophy, rapidly progressive (lethal) -upper & lower motor neurons, bulbar weakness -normal sensation[] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[] These include criteria for the diagnosis of multiple sclerosis, dementia of Lewy-body type, frontal lobe dementias, chronic fatigue syndrome, and inflammatory neuropathies[]

  • Neurosyphilis

    […] paresis and hyperreflexia 7,8 occurs months to years after infection 3,4 meningovascular syphilis prodrome of mild clinical features of syphilitic meningitis 4,9 this is[] The patient reported asthenia (abnormal loss of strength), weight loss, and bilateral red, painful eyes. He also reported severe vision loss, which had been progressive.[] Neurosyphilis should not be overlooked as an etiology for progressive dementia even in this post-antibiotic era.[]

  • Amyotrophic Lateral Sclerosis Type 1

    hyperreflexia ( ) Hoffman's ( ) Babinski's spastic dysarthria lower motor neuron (LMN) signs muscular atrophy weakness clinical fasciculations clumsiness Evaluation Diagnosis[] […] positive effect on functional abilities from the use of riluzole is unclear, and no studies have reported that the drug halts the disease process. 21 Adverse effects include asthenia[] ALS amyotrophic lateral sclerosis with dementia Charcot disease dementia with amyotrophic lateral sclerosis Lou Gehrig disease motor neuron disease, amyotrophic lateral sclerosis[]

  • Friedreich Ataxia

    His examination was significant for spastic gait, hyperreflexia, and sensory neuropathy. Genetic testing revealed a compound heterozygous mutation in the FXN gene.[] Adverse effects One participant in Zannolli 2012 (total of 13 enrolled participants) experienced asthenia during drug tapering, which did not require medical intervention.[] Program at Tufts Medical Center in Boston to learn more about treating degenerative brain disease and other types of dementia.[]

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