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94 Possible Causes for Asthenia, Dysarthria, Spasticity - Hyperreflexia

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[icdlist.com] A 28-year-old woman developed progressive spastic gait and dysarthria.[ncbi.nlm.nih.gov] ., adj sclerot ic. familial centrolobar sclerosis a progressive familial form of leukoencephalopathy marked by nystagmus, ataxia, tremor, parkinsonian facies, dysarthria,[medical-dictionary.thefreedictionary.com]

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[en.wikipedia.org] The severe dysarthria subsequently evolved into anterior opercular syndrome.[ncbi.nlm.nih.gov] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[symptoma.com]

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[aafp.org] The symptoms of this condition include dysphagia, pain in the joints or dysarthria, seizures, confusion, loss of consciousness and paralysis of all four limbs.[news-medical.net] CASE: A 17-year-old boy was admitted to the emergency department with abdominal pain, nausea and vomiting, asthenia, and weight loss.[ncbi.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis

    The upper motor signs include spasticity, hyperreflexia and weakness. The lower motor signs include amyotrophy, weakness and fasciculations.[symptoma.com] […] progression are available for ALS, but patient management is largely mediated by symptomatic therapies, such as the use of muscle relaxants for spasticity and speech therapy for dysarthria[ncbi.nlm.nih.gov] Asthenia There was a trend toward more asthenia among the treated participants in each trial, and this became statistically significant when the data from the three trials[doi.org]

  • Radiculomyelopathy

    Myelopathic features are characterized by a more abrupt onset and include spastic paraplegia or quadriplegia, hyperreflexia, Babinski reflex, clonus, or a variety of sensory[fluoridealert.org] Other symptoms are difficulty eating, drooling, dysarthria, dysphonia, choking events with meals, nasal regurgitation of fluids or pulmonary aspiration.[patient.info] Lower motor neuron findings include atrophy, hypotonia, cramps, fasciculations, hyporeflexia, weakness, and bulbar dysarthria.[consultant360.com]

  • Infantile Neuroaxonal Dystrophy

    Clinical Onset before age three years Psychomotor regression (most common presenting feature) Early truncal hypotonia followed by spastic tetraparesis (usually with hyperreflexia[ncbi.nlm.nih.gov] Tetraparesis occurs late in the disease and is not necessarily preceded by truncal hypotonia and patients are more likely to have progressive dystonia and dysarthria.[orpha.net] Common muscle symptoms: -Involuntary muscle contractions (dystonia) -Poor articulation and speech (dysarthria) -Muscle tightness and weakness in both arms and legs -Reduced[rarediseases.org]

  • Friedreich Ataxia

    His examination was significant for spastic gait, hyperreflexia, and sensory neuropathy. Genetic testing revealed a compound heterozygous mutation in the FXN gene.[ncbi.nlm.nih.gov] Here we aimed to compare dysarthria profiles of patients with (SCA3 and SCA6 vs.[ncbi.nlm.nih.gov] Adverse effects One participant in Zannolli 2012 (total of 13 enrolled participants) experienced asthenia during drug tapering, which did not require medical intervention.[doi.org]

  • Amyotrophic Lateral Sclerosis Type 10

    Upper motor neuron findings in ALS include hyperreflexia and spasticity. amyotrophy and fasciculations. bowel and bladder dysfunction.[journals.lww.com] […] positive effect on functional abilities from the use of riluzole is unclear, and no studies have reported that the drug halts the disease process. 21 Adverse effects include asthenia[aafp.org] Clinical Loss of fine motor skills, triad of atrophic weakness of hands and forearms; leg spasticity; generalised hyperreflexia. Management Possibly riluzole.[medical-dictionary.thefreedictionary.com]

  • Ataxia

    Typical clinical signs and symptoms of autosomal dominant ataxias (ADCA) include the following: Limb and truncal ataxia Hyperreflexia and spasticity (pyramidal signs) are[centogene.com] Patient 2 initially presented with an increased startle response and myoclonic jerks, and subsequently developed severe limb and gait ataxia, dysarthria, oculomotor disturbances[ncbi.nlm.nih.gov] This results in a characteristic type of irregular, uncoordinated movement that can manifest itself in many possible ways, such as asthenia, asynergy, delayed reaction time[en.wikipedia.org]

  • Postencephalitic Parkinson Disease

    Unlike Parkinson disease, corticospinal tract lesions cause Paresis (weakness or paralysis), preferentially in distal antigravity muscles Hyperreflexia Extensor plantar responses[msdmanuals.com] These often include the following: Fatigue or general malaise Trembling Difficulty arising from a seated position Lowered voice volume (dysarthria) Small, cramped, spidery[neurosurgeonsofnewjersey.com] The former typically arose on the heels of febrile upper respiratory infection and was characterized by somnolence, asthenia, ocular palsies, and a wide variety of movement[indiana.pure.elsevier.com]

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