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12 Possible Causes for Asthenia, Skeletal Muscle Fasciculation, Spasticity - Hyperreflexia

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[] Symptoms may include hypotonia (severely reduced muscle tone), diminished limb movements, lack of tendon reflexes, fasciculations, tremors, swallowing and feeding difficulties[] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[]

  • Amyotrophic Lateral Sclerosis

    The upper motor signs include spasticity, hyperreflexia and weakness. The lower motor signs include amyotrophy, weakness and fasciculations.[] Asthenia There was a trend toward more asthenia among the treated participants in each trial, and this became statistically significant when the data from the three trials[] Sleep-related leg muscle cramps and fasciculations Degeneration of the lower motoneurons causes fasciculations in skeletal muscles which may be reported to disrupt sleep by[]

  • Muscular Fasciculation

    Upper motor neuron lesions are characterized by weakness, spasticity, hyperreflexia, primitive reflexes and the Babinski sign.[] […] positive effect on functional abilities from the use of riluzole is unclear, and no studies have reported that the drug halts the disease process. 21 Adverse effects include asthenia[] Benign fasciculation syndrome is a mild neurological disorder that is characterized by involuntary twitching of skeletal muscles at rest.[]

  • Lower Motor Neuron Syndrome with Late-Adult Onset

    , spasticity -muscle atrophy (fasciculations), fasciculations, tongue atrophy, rapidly progressive (lethal) -upper & lower motor neurons, bulbar weakness -normal sensation[] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[] Symptoms include fatigue, slowly progressive muscle weakness, muscle atrophy, fasciculations, cold intolerance and muscle and joint pain.[]

  • Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset

    , weakness and hyperreflexia where the progressive bulbar involvement causes bulbar symptoms such as dysarthria and dysphagia.[6],[4].[] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[] It is a fatal disorder and is characterized by progressive skeletal muscle weakness and wasting or atrophy (ie, amyotrophy), spasticity, and fasciculations as a result of[]

  • Neuromuscular Junction Disorder

    Upper motor neuronal dysfunction lead to spasticity and hyperreflexia while lower motor neuronal lesions lead to paralysis with muscle fasciculations.[] In NMJD breathiness and asthenia are frequently present with variable degree and fluctuating pattern during the day.[] The neuronal hyperexcitability results in skeletal muscle overactivity, which manifests as muscle twitching or myokymia (which is often confused with fasciculation), cramps[]

  • Neurogenic Arthrogryposis Multiplex Congenita

    Dysarthria Hyperreflexia Enlarged cisterna magna Abnormality of the skeletal system Vomiting Babinski sign Clinodactyly Dementia Gastroesophageal reflux Pes cavus Microcornea[] Claude Stoll, Marie‐Christine Ehret‐Mentre, Alain Treisser and Christine Tranchant, Prenatal diagnosis of congenital my asthenia with arthrogryposis in a myasthenic mother[] […] maturation Severe muscular hypotonia Hyperkeratosis Myopia Hiatus hernia Sleep disturbance Atrophic scars Inguinal hernia Nystagmus Skin dimples Proximal muscle weakness[]

  • Proximal Myopathy with Extrapyramidal Signs

    The essential clinical findings are slowly progressive and often include severe spasticity, hyperreflexia, and weakness in a pyramidal distribution, noticeably in both lower[] Other side effects include: persistent ventricular tachycardia, pneumonitis, bradycardia, abnormal hepatic function tests, nausea, abnormal gait, asthenia, constipation, cough[] Thus, weakness accompanied by spasticity, hyperreflexia, and Babinski responses (up-going toes) suggests upper motor neuron dysfunction.[]

  • Scorpion Envenomation

    There was a right facial nerve palsy (upper motor neuron type); right spastic hemiplegia with hyperreflexia and extensor plantar response. Fundoscopy was unremarkable.[] However, one hour after being stung, the patient continued to complain of asthenia and general malaise, symptoms generally not attributed to Euscorpius sting, which was presumably[] The most common skeletal neuromuscular dysfunctions include: agitation restlessness skeletal muscle fasciculations opisthotonos (severe spasm of the spinal muscles causing[]

  • Arthrogryposis, Perthes Disease and Upward Gaze Palsy

    […] tract - truncal hypotonia in first year - spasticity, hyperreflexia, clonus in 2nd year 2. 2nd most common - due to cerebellar injury - affects fine coordinated movements[] Still's disease or syndrome 714.30 Still-Felty syndrome (rheumatoid arthritis with splenomegaly and leukopenia) 714.1 Stillbirth, stillborn NEC 779.9 Stiller's disease (asthenia[] muscle atrophy Oral aversion Multiple plantar creases Multiple palmar creases Eyelid fasciculation Functional abnormality of the gastrointestinal tract Arthrogryposis multiplex[]

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