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60 Possible Causes for Asthenia, Spasticity - Hyperreflexia, Unable to Walk

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[icdlist.com] , or brace for distances of 100 meters or more. 7.0 : Unable to walk 5 meters even with an aid.[medicalnewstoday.com] However, a person's disability is severe enough to limit full daily activities, such as working full time. 6.0 : Needs occasional or everyday help, walking with a cane, crutch[medicalnewstoday.com]

  • Radiculomyelopathy

    Myelopathic features are characterized by a more abrupt onset and include spastic paraplegia or quadriplegia, hyperreflexia, Babinski reflex, clonus, or a variety of sensory[fluoridealert.org] […] to walk unaided by 1 year. 30 Between the years 2000-2004, inpatient mortality rate for GBS in U.S. hospitals was 2.58%. 23 Predictors of mortality included endotracheal[consultant360.com] […] unassisted Grade 4 Unable to walk without assistance Grade 5 Wheelchair or bedbound Based on gait and ambulatory function Ranawat Classification Class I Pain, no neurologic[orthobullets.com]

  • Motor Neuron Disease

    Lower motor neuron (LMN) findings include muscle atrophy and fasciculations, and upper motor neuron (UMN) findings include hyperreflexia, spasticity, muscle spasm, and abnormal[en.wikipedia.org] Over time, the patient will lose the use of their muscles and be unable to walk, stand or sit without assistance. Eventually, they’ll need help eating and breathing.[alsnewstoday.com] , hyperreflexia and atrophy in later stages of disease, but fasciculations are absent.[symptoma.com]

  • Infantile Neuroaxonal Dystrophy

    Clinical Onset before age three years Psychomotor regression (most common presenting feature) Early truncal hypotonia followed by spastic tetraparesis (usually with hyperreflexia[ncbi.nlm.nih.gov] Most boys are unable to walk by age 12, and later need a respirator to breathe.[ninds.nih.gov]

  • Muscle Spasticity

    Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS.[profiles.umassmed.edu] The most commonly reported adverse effects in the tizanidine group were drowsiness, xerostomia (P 0.001) and asthenia (not significant).[doi.org] […] to walk.[mattsms.com]

  • Lower Motor Neuron Syndrome with Late-Adult Onset

    , spasticity -muscle atrophy (fasciculations), fasciculations, tongue atrophy, rapidly progressive (lethal) -upper & lower motor neurons, bulbar weakness -normal sensation[brainscape.com] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[neuroweb.us] […] to walk unaided by 1 year. 30 Between the years 2000-2004, inpatient mortality rate for GBS in U.S. hospitals was 2.58%. 23 Predictors of mortality included endotracheal[consultant360.com]

  • Paraneoplastic Neurologic Syndrome

    Given that the index patient presented with hyperreflexia and a positive Babinski reflex, it is of note that mutations in beta-NAP have been proposed to play a role in spastic[jneuroinflammation.com] A 49-year-old woman presented with a history of progressive asthenia of the lower extremities persisting for 2 months.[ncbi.nlm.nih.gov] A 79-year-old man with Parkinson's disease was unable to walk because of paralysis. Brain MRI showed cerebellar atrophy.[dear-medic.jp]

  • Diomedi-Bernardi-Placidi Syndrome

    , hyperreflexia, urinary bladder disturbance (hypertonic bladder) and extensor plantar responses with weakness of a pyramidal distribution in the lower limbs.[ruralneuropractice.com] […] inclusions in erythrocytes XNP , (XH2) Xq13.3 Christianson syndrome Short stature, microcephaly, long narrow face, large ears, long straight nose, prominent mandible, general asthenia[pediatrics.aappublications.org] Individuals with severe symptoms may be unable to walk independently. In general, however, HSP does not shorten lifespan.[rarediseases.org]

  • Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset

    , weakness and hyperreflexia where the progressive bulbar involvement causes bulbar symptoms such as dysarthria and dysphagia.[6],[4].[explainmedicine.com] Approximately 10% of patients stop the drug because of adverse events, principally gastrointestinal intolerance and asthenia.[neuroweb.us] Standing is also a very important part of a physical management programme for many individuals with neuromuscular conditions, even if you are unable to walk independently.[smasupportuk.org.uk]

  • Amyotrophic Lateral Sclerosis

    The upper motor signs include spasticity, hyperreflexia and weakness. The lower motor signs include amyotrophy, weakness and fasciculations.[symptoma.com] Asthenia There was a trend toward more asthenia among the treated participants in each trial, and this became statistically significant when the data from the three trials[doi.org] hyperreflexia ( ) Hoffman's ( ) Babinski's spastic dysarthria lower motor neuron (LMN) signs muscular atrophy weakness clinical fasciculations clumsiness Evaluation Diagnosis[orthobullets.com]

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