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127 Possible Causes for Astrocytic Gliosis, Lethargy

  • Leigh's Disease

    A 7-month-old boy presented clinically with vomiting, lethargy, respiratory difficulty, deteriorated consciousness, and hypotonia.[ncbi.nlm.nih.gov] In addition, there was severe leukoencephalopathy of the cerebral hemispheres with sudanophilic tissue degregation, advanced axonal loss and reactive astrocytic gliosis.[ncbi.nlm.nih.gov] Clinical findings included irregular breathing, lethargy, and inability to feed.[ajnr.org]

  • Chronic Fatigue Syndrome

    Ongoing flu-like symptoms: including sore throats and enlarged glands, fever-like sweats, lethargy.[patient.info] PubMed Google Scholar Hwang SY, Jung JS, Kim TH, Lim SJ, Oh ES, Kim JY, Ji KA, Joe EH, Cho KH, Han IO: Ionizing radiation induces astrocyte gliosis through microglia activation[doi.org] Stimulants: Stimulants may be used to treat lethargy or daytime sleepiness.[emedicinehealth.com]

  • Hypoxia

    Signs: Rapid Breathing Cyanosis Poor Coordination Lethargy/Lassitude Executing Poor Judgment Symptoms: Air Hunger Dizziness Headache Mental and Muscle Fatigue Nausea Hot and[favoriteplus.com] After 20 weeks' gestation, hypoxic-ischemic insults result in astrocyte activation with subsequent gliosis.[emedicine.medscape.com] The symptoms in pediatric patients can be similar to the above and may include the following: Lethargy Irritableness Anxiousness Inattentiveness Sitting up and leaning forward[medicinenet.com]

  • Pallidopyramidal Syndrome

    Onset started with general weakness, muscle stiffness and lethargy and progressed rapidly to a deterioration of motor function accompanied by involuntary jerky movements,[cags.org.ae] Neuronal degeneration and gliosis in the surrounding areas firstly involve astrocytes [ 40 ], initially causing hypertrophy and hyperplasia, and finely leading to necrosis[bmcneurol.biomedcentral.com] Autistic behavior Difficulty running Sensorineural hearing impairment Visual impairment Optic atrophy Blindness Abnormality of the nervous system Abnormality of the eye Lethargy[mendelian.co]

  • Intracranial Abscess

    Symptoms may include headache, lethargy, fever, and focal neurologic deficits. Diagnosis is by contrast-enhanced MRI or CT.[merckmanuals.com] , gliosis, and cerebral edema external to the capsule. [6] The CT appearance of well-encapsulated abscesses showed a typical ring-shaped contrast-enhancing lesion.[asianjns.org] He displayed an acute onset of confusion, lethargy, unstable gait and neck stiffness.[jcda.ca]

  • Multiple Sclerosis

    The signs and symptoms of multiple sclerosis in children and teens are similar to those experienced by adults; however, they also may have seizures and extreme fatigue or lethargy[emedicinehealth.com] Multiple sclerosis (MS) is characterised by inflammation, demyelination, axonal or neuronal loss, and astrocytic gliosis in the central nervous system (CNS), which can result[ncbi.nlm.nih.gov] […] pediatric MS have the relapsing-remitting MS type; however, additional symptoms often not experienced in adults with MS may include seizures and mental status changes like lethargy[medicinenet.com]

  • Central Pontine Myelinolysis

    A 26-year-old man with a history of chronic alcohol abuse presented with dysarthria, lethargy, and horizontal nystagmus.[nejm.org] gliosis.[ispub.com] Common symptoms included lethargy and dysarthria. Five of the 6 patients had chronic alcoholism.[ncbi.nlm.nih.gov]

  • Anti-NMDA Receptor Encephalitis

    […] behaviour, disorientation, confusion, paranoid thoughts, visual or auditory hallucinations and memory deficits In the following phase, decreased consciousness, hypoventilation, lethargy[lifeinthefastlane.com] […] of various serum proteins and the reactivity of proximal microglia and astrocytes in the uninjured brainstem and spinal cord enlargements after 1-4 weeks.[ncbi.nlm.nih.gov] To study the equivocal relationship between serum protein extravasation and reactive gliosis, we injected C57BL/6 mice with CFA and histologically assessed the permeability[ncbi.nlm.nih.gov]

  • Pilocytic Astrocytoma

    We report a case of a 47-year-old man presenting with sudden-onset frontal headache associated with nausea and lethargy in addition to a background of a longer history of[ncbi.nlm.nih.gov] […] associated with intense fibrillary gliosis. 6, 11 – 13 On light microscopy, these acidophilic structures stain bright red with eosin (Fig 1). 6, 12, 14 With phosphotungstic[ajnr.org] Common findings (often caused by pressure within the brain from a large tumor or blockage of the flow of cerebrospinal fluid include, lethargy, headaches, drowsiness, clumsiness[nicklauschildrens.org]

  • Hyperalaninemia

    Signs and symptoms of hyperbetaalaninemia includeconvulsions (rapid and uncontrollable shaking), lethargy , and encephalopathy .Hyperbetaalaninemia is thought to be due to[monarchinitiative.org] Central nervous system neuropathology may include poor myelination, paucity of cerebral cortex neurons, gliosis, and proliferation of astrocytes.[emedicine.medscape.com] Signs and symptoms of hyperbetaalaninemia include convulsions (rapid and uncontrollable shaking), lethargy, and encephalopathy.[rarediseases.info.nih.gov]

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