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125 Possible Causes for Astrocytic Gliosis, Sleep Disturbance

  • Classic Progressive Supranuclear Palsy Syndrome

    Neuropathologically, all forms are characterized by neuronal loss, gliosis with astrocytic plaques and accumulation of tau-immunoreactive neurofibrillary tangles in specific[orpha.net] Some patients experience sleep disturbances such as frequent awakenings and changes in sleeping patterns.[rarediseases.org] The disease is characterized neuropathologically by gliosis with astrocytic plaques, accumulation of tau-immunoreactive neurofibrillary tangles and neuronal loss in specific[orpha.net]

  • Alzheimer Disease

    Multifocal spongiform encephalopathic changes, mononuclear perivascular infiltrates, subcortical demyelination and gliosis were also found.[ncbi.nlm.nih.gov] The aims of this study were to determine the prevalence of symptoms of disturbed sleep in patients with AD, identify the care-recipient sleep disturbance symptoms that predict[ncbi.nlm.nih.gov] Vitiello, Sleep disturbances in Alzheimer’s disease, Clinical Pharmacology of Sleep, 10.1007/3-7643-7440-3_11, (173-182), (2006). Marsha L.[doi.org]

  • Chronic Fatigue Syndrome

    PubMed Google Scholar Hwang SY, Jung JS, Kim TH, Lim SJ, Oh ES, Kim JY, Ji KA, Joe EH, Cho KH, Han IO: Ionizing radiation induces astrocyte gliosis through microglia activation[doi.org] STUDY OBJECTIVES: Little is known about the type and severity of sleep disturbances in the pediatric chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) population[ncbi.nlm.nih.gov] Unrefreshing sleep was the only criteria relating to sleep, with other sleep disturbances not a criterion.[doi.org]

  • Anti-NMDA Receptor Encephalitis

    […] of various serum proteins and the reactivity of proximal microglia and astrocytes in the uninjured brainstem and spinal cord enlargements after 1-4 weeks.[ncbi.nlm.nih.gov] Griffiths, Primary sleep disorders can cause long-term sleep disturbance in patients with autoimmune mediated limbic encephalitis, Clinical Neurology and Neurosurgery, 115[doi.org] Flu-like symptoms Memory deficits, including loss of short-term memory; Sleep disorders; Speech dysfunction – the patient is no longer able to produce coherent language or[antinmdafoundation.org]

  • Mucopolysaccharidosis 1

    , 16, 18, 21, 32, 33 leading to neuronal loss, gliosis, delayed myelination, or/and demyelination. 9, 10, 18, 21, 26, 32 Among other theories, increase of fluid content in[ajnr.org] Sleep disturbances due to respiratory insufficiency may be experienced and patients may claim a hearing loss. Some patients present with macroglossia.[symptoma.com] disturbances/snoring (51.6%) Splenomegaly (50.9%) Cardiac valve abnormalities (48.9%) Cognitive impairment (46.4%) Dystosis multiplex (43.6%) Enlarged tongue (41.3%) Joint[oncofertility.northwestern.edu]

  • Fatal Familial Insomnia

    Overall, 20 of 21 patients showed FFI typical neuropathological findings with prominent thalamo-olivaric pathology. 27 Severe astrocytic gliosis and nerve cell loss but weak[jnnp.bmj.com] According to this diagnostic pathway, organic sleep disturbance is the most frequent and essential symptom of FFI. [3] Consistent with this description, sleep disturbances[journals.lww.com] C : Immunohistochemistry for glial fibrillary acidic protein (GFAP) reveals reactive astrocytic gliosis in the mediodorsal thalamic nucleus of the present case but not in[biomedcentral.com]

  • Alexander Disease

    KEYWORDS: Alexander disease; Rosenthal fibers; astrocyte; glia; gliosis; neurodegenerative diseases[ncbi.nlm.nih.gov] A 51-year-old patient was diagnosed with AxD at the age of 47, following an 8-year history of vertigo, intermittent diplopia, and sleep disturbance.[ncbi.nlm.nih.gov] In addition, sleep disturbance (mainly sleep apnea), symptoms of dysautonomia, and dysmorphism were found in all affected individuals.[jamanetwork.com]

  • Parkinson's Disease

    Because Ret is not genetically ablated in astrocytes, these results suggest that the gliosis in the striatum of DAT-Ret lx/lx mice is non-cell autonomously caused by degenerating[ncbi.nlm.nih.gov] According to the Parkinson's disease Sleep Scale (PDSS), 15 (53.58%) patients had severely disturbed sleep.[ncbi.nlm.nih.gov] This study aimed to explore the correlations of serum CysC levels and objective sleep disturbances in early PD.[ncbi.nlm.nih.gov]

  • Striatonigral Degeneration

    Neuropathologic findings are severe neuronal loss and astrocytic gliosis in the corpus striatum and substantia nigra, with a moderate neuronal loss in the dentate nucleus[ncbi.nlm.nih.gov] Both the REM sleep disturbance and sleep apnea are caused by central disease.[dizziness-and-balance.com] The subthalamicus nuclei showed loss of neurons and gliosis. The thalamus was unchanged.[dokumen.tips]

  • Creutzfeldt Jakob Disease

    gliosis; however, a reduction of ADCs correlated with astrocytic gliosis and also with spongiform changes and nerve cell loss.[ajnr.org] Abstract Background: The prevalence and characteristics of sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease (sCJD) are poorly understood.[neurology.org] Standard polysomnography was performed after a brief interview confirming the presence of sleep disturbances.[ncbi.nlm.nih.gov]

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