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137 Possible Causes for Astrocytic Gliosis, Sudden Death

  • Globoid Cell Leukodystrophy

    ] a metabolic disorder of infancy or early childhood characterized by spasticity, seizures, and rapidly progressive cerebral degeneration, massive loss of myelin, severe astrocytic[] The presence of numerous, often multinucleated, globoid cells, the almost total loss of myelin and oligodendroglia, and astrocytic gliosis in the white matter are the morphologic[] gliosis through astrocytic PGD2 receptors (DP1).[]

  • Status Epilepticus

    Pathologic findings of the gyrus around the tumor revealed mild gliosis with proliferating astrocytes but no evidence of glioma.[] […] unexpected death in epilepsy (SUDEP) is a frequent cause of non-accidental, non-suicidal sudden death in patients with epilepsy.[] Prognosis Status epilepticus is the second highest cause of mortality in Dravet syndrome patients, following sudden unexpected death in epilepsy ( SUDEP ). *** Dravet Syndrome[]

  • Sudden Infant Death Syndrome

    SIUD cases (aged 25 to 30 gestational weeks) the main defects were: tanycytes only rarely present; atrophy of the cilia; and a low number of apoptotic cells and reactive astrocytes[] […] category) Crib death Sudden infant death syndrome[] […] cases (from 38 to 41 gestational weeks) we frequently observed: micro- or macro-areas of EP desquamation and/or discontinuity on the ventricular surface (Figure 6a ); marked gliosis[]

  • Cerebellar Hemorrhage

    Gliosis was defined as the occurrence of 11 or more reactive astrocytes with abundant eosinophilic cytoplasm and an eccentrically situated nucleus with delicate chromatin[] […] even sudden death. [2], [3], [4], [5], [6], [7] Here, we report the case of a child, whose first presentation of medulloblastoma was a fatal cerebellar hemorrhage and discuss[] In rare cases, an acute intratumoral hemorrhage may be the initial presentation of medulloblastoma; this presentation can also lead to sudden neurological deterioration and[]

  • Amyotrophic Lateral Sclerosis

    Pathology Atrophy of the anterior horn cells and replacement of the large motor neurons by fibrous astrocytes (gliosis) causes the affected anterior and lateral columns of[] Upper motor neurone pathology in ALS is indicated by depopulation of the Betz cells in the motor cortex (Brodmann area 4), variable astrocytic gliosis affecting both the grey[] Histopathological features The pathological hallmarks of ALS are the degeneration and loss of motor neurones with astrocytic gliosis and the presence of intraneuronal inclusions[]

  • Progressive Multifocal Leukoencephalopathy

    ; reactive gliosis Unusual astrocytes may cause confusion with glioma on biopsy Minimal inflammation Immunohistochemistry – JCV staining in oligodendroglial cells and astrocytes[] Symptoms include sudden fever, severe headache, or confusion. Infection of the eye caused by herpes viruses leading to blindness in some patients has occurred.[] […] with enlarged astrocytes 13.[]

  • Diffuse Cerebral Sclerosis of Schilder

    […] and scattered astrocytes with absence of oligodendroglia, axons, myelin, and inflammatory cells (, 2 ).[] Death Pediatric Age 460 Sudden Death Young Athlete 461 Syncope 462 Tabes Dorsalis 463 Tardive Dyskinesia 464 Taste and Smell Loss 465 Testicular Failure 466 Testicular Neoplasm[] […] syndrome, sudden unexplained nocturnal death syndrome, sunds Ontology Lookup Service CADASIL cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy[]

  • Myotonic Dystrophy

    GFAP immunohistochemistry evidenced astrocytic gliosis in the frontal, temporal and parahippocampic cortex.[] Sudden death was defined as death occurring suddenly and unexpectedly in a patient who was stable before the event. 21,22 Witnessed deaths were classified as sudden only if[] We studied the association between CTG expansion size and other baseline characteristics and (1) cardiac involvement at baseline and (2) the incidence of death, sudden death[]

  • Epilepsy

    Astrocyte reactivity Evidence suggests that the BBB disruption contributes to astrocyte activation and gliosis.[] Ferraz, Sudden unexpected death in Parkinson's disease: Perspectives on what we have learned about sudden unexpected death in epilepsy (SUDEP), Epilepsy & Behavior, 10.1016[] KEYWORDS: Biomarkers; Epilepsy; Forensic preventative pathology; MiRNA; Sudden death[]

  • McLeod Neuroacanthocytosis Syndrome

    Marked neuronal loss and astrocytic gliosis were observed on histologic examination.[] Other research is aimed at identifying possible causes of sudden death related to heart muscle abnormalities, which are observed in some individuals with neuroacanthocytosis[] Sudden, apparently unexplained death seems to occur quite frequently in ChAc.[]

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