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490 Possible Causes for Asymmetric Nipples, Bifid Tip of Nose, Clenched Hands

  • Malpuech Syndrome

    hands, rocker bottom feet, cardiac defects –van der Woude syndrome: Cleft palate associated with lip pits * Cause associated with maternal exposure to corticosteroids, phenytoin[checkorphan.org] Prominent coccyx/caudal appendage Mental retardation Postnatal growth deficiency Telecanthus Bifid tip of the nose Dysplastic/low set ears Down-turned corners of the mouth[documents.tips] […] chest; [Breasts]; Abnormally placed nipples; Accessory nipple GENITOURINARY: [External genitalia, male]; Micropenis; Hypospadias; [Internal genitalia, male]; Cryptorchidism[findzebra.com]

  • Craniofrontonasal Dysplasia

    Main features of this condition include widely spaced eyes ( hypertelorism ), bifid tip of the nose, broad head (brachycephaly), prominent forehead ( frontal bossing ), asymmetry[rarediseases.info.nih.gov] nipples and volume, webbed neck, hand or foot abnormalities such as clinodactyly (most common is a curved 5th finger) and cutaneous syndactyly (webbed fingers / toes).Females[en.wikipedia.org] Zone of the nose Nearly, all patients (91%, n 21) displayed a bifid tip of the nose.[nature.com]

    Missing: Clenched Hands
  • Microphthalmia Type Lenz

    Summary Clinical characteristics. Lenz microphthalmia syndrome (LMS) is characterized by unilateral or bilateral microphthalmia and/or clinical anophthalmia with malformations of the ears, teeth, fingers, skeleton, and/or genitourinary system. Microphthalmia is often accompanied by microcornea and glaucoma. Coloboma is[…][ncbi.nlm.nih.gov]

    Missing: Asymmetric Nipples
  • Bifid Nose

    Learn more: A: Bifid tip All noses are structurally bifid--two distinct cartilages.[realself.com] A low implantation of the breasts was seen in the majority of patients (19/21), and in addition most of them had asymmetrical heights of their nipples (11/19).[nature.com] The presentation of a bifid nose ranges from a minimally noticeable midline nasal tip central groove to a complete clefting of the osteocartilaginous framework, resulting[ncbi.nlm.nih.gov]

    Missing: Clenched Hands
  • Frontonasal Dysplasia

    Frontonasal dysplasia is defined as hypertelorism, telecanthus and broad bridge of the nose with absent or bifid tip of the nose.[ncbi.nlm.nih.gov] Nipples were placed widely and asymmetrically. Examination of the spine revealed scoliosis in the thoracolumbar region.[mjdrdypu.org] Frontonasal dysplasia (FND) is a genetically heterogeneous malformation spectrum with marked hypertelorism, broad nasal tip and bifid nose.[ncbi.nlm.nih.gov]

    Missing: Clenched Hands
  • Patau Syndrome

    Symptoms of the Disease are Extra fingers, decreased muscle tone, clenched hands, small eyes, small head, scalp defects etc.[omicsonline.org] hand with finger overlap, rocker bottom feet, micrognathia, low set ears Image depicting classic appearance of clenched hand with overlapping 2nd and 5th fingers in a newborn[pedclerk.bsd.uchicago.edu] Other birth defects of trisomy 13 include: Clenched hands Cleft lip or palate Extra fingers or toes (polydactyly) Hernias Kidney, wrist, or scalp problems Low-set ears Small[webmd.com]

    Missing: Asymmetric Nipples Bifid Tip of Nose
  • Trisomy 18

    At least 30% of affected fetuses have abnormal extremities (unilateral or bilateral), the most frequent one being clenched hand and radial aplasia.[humpath.com] hand with overlapping fingers and general hypertonia, is presented.[ncbi.nlm.nih.gov] hands, ventricular septal defect, coarctation of the aorta, patent ductus arteriosus, Meckel's diverticulum, ectopic pancreas in the ileum, and DWM.[ncbi.nlm.nih.gov]

    Missing: Asymmetric Nipples Bifid Tip of Nose
  • Partial Trisomy 13 in Patau Syndrome

    hand with finger overlap, rocker bottom feet, micrognathia, low set ears Image depicting classic appearance of clenched hand with overlapping 2nd and 5th fingers in a newborn[pedclerk.bsd.uchicago.edu] Symptoms Cleft lip or palate Clenched hands (with outer fingers on top of the inner fingers) Close-set eyes -- eyes may actually fuse together into one Decreased muscle tone[dxline.info] Clenched hand with overlapping fingers. C. Postaxial polydactyly. D. Equinovarus deformity. E. Punched out aplasia cutis scalp lesions.[pedclerk.bsd.uchicago.edu]

    Missing: Asymmetric Nipples Bifid Tip of Nose
  • Craniosynostosis

    Second-trimester molecular prenatal diagnosis of sporadic Apert syndrome following sonographic findings of mild ventriculomegaly and clenched hands mimicking trisomy 18.[eyewiki.aao.org] nipples, bifid digits and agenesis of the corpus callosum. 30 The identification of causative mutations in EFNB1, which confer loss of function and are correspondingly diverse[nature.com] […] hypertelorism, unicoronal or bicoronal synostosis, bifid nasal tip, characteristic longitudinal nail splits ( Figure 1m and o ) and, at lower frequency, sloping shoulders, asymmetric[nature.com]

    Missing: Bifid Tip of Nose
  • Femoral Agenesis - Femoral Hypoplasia

    bifid tip Thin lips Long philtrum Low set ears Anteverted / prominent / bat ears Sprengel anomaly Inguinal hernia Scoliosis Limb deficiency - ray Bony restriction of joint[mediscansystems.org] The fist is often clenched. Ideally watch the hand open/close and check for 5 fingers/knuckles on each side.Check for the presence of the 5th middle phalanx.[ultrasoundpaedia.com] […] hemihypertrophy / hemiatrophy Short stature - prenatal / intrauterine dwarfism Short stature - postnatal Short limbs Skin dimples Pointed chin Depressed nasal bridge Cleft nose[mediscansystems.org]

    Missing: Asymmetric Nipples