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22 Possible Causes for Asymmetric Nipples, Growth Retardation, Malignant Melanoma

  • Congenital Nevus

    LEOPARD is an acronym for lentigines, electrocardiographic abnormalities, ocular hypertelorism, pulmonary stenosis, abnormalities of genitalia, retardation of growth, and[journals.lww.com] More than a half of the patients in which malignant melanoma developed in giant congenital nevi were under the age of 10.[ncbi.nlm.nih.gov] We report a 26-year-old male with a 4 mm diameter, asymmetric, irregularly pigmented and bordered, brown maculopapular lesion on the right nipple present since childhood with[ncbi.nlm.nih.gov]

  • Noonan Syndrome

    Facial dysmorphism, growth retardation, and various heart defects are typical clinical features. In patients with minor cardiac pathology, life expectancy is normal.[ncbi.nlm.nih.gov] […] tumour samples: p.G248R (glioma, large intestine carcinoma and melanoma) and p.R284C (endometrium carcinoma) in the catalogue of somatic mutations in cancer (COSMIC database[jmg.bmj.com] In addition, nipples were wide-spaced and appeared to be low-set. On genital examination, testicles appeared to be small.[jiaomr.in]

  • Monosomy 1p36 Syndrome

    Terminal deletions of the short arm of chromosome 1 are associated with hypotonia and developmental delay (usually severe), growth abnormalities (growth retardation, microcephaly[jmg.bmj.com] Furthermore, chromosome Ip36 deletions have also been reported to occur in various neoplasms, including neuroblastoma, prostate cancer, lung cancer, malignant melanoma, hepatoma[google.ch] […] rotated ears Low-set ears Small mouth Down turned corners of the mouth Long philtrum Pointed chin Micro/retrognathia High arched palate Webbed neck Short neck Hypoplastic nipples[enlivenarchive.org]

  • Ring Chromosome 19

    retardation * Motor retardation * Mental retardation * Deafness * Autism Causes - Chromosome 19 ring syndrome * Clubfoot * Deafness * Growth retardation * High forehead *[checkorphan.org] melanoma pter qter 8428043 Edit 37 10594874_2 46, XY [293]/ 47, XY, 7 [56]/ 46, XY, r(7) [60]/ 47, XY, 7, r(7)[2] intrauterine growth retardation, short stature, moderate[chr7.org] […] and dysmorphic ears with prominent helix, spaced nipples, and tapering fingers (Fig. 1).[ssmc-tl.com]

  • Central Precocious Puberty

    At birth she presented growth retardation and congenital anomalies (ventricular septal defect, macroglossia, umbilical hernia).[ncbi.nlm.nih.gov] Critical thinking a statement of expert consensus ul adha Eid festival essay argumentative essay topics on animals not criminally responsible essay case study malignant melanoma[eventi.nerobold.com] Initially, breast budding may be unilateral or asymmetric.[emedicine.medscape.com]

  • Familial Neutropenia

    […] failure Barth syndrome TAZ XL Cardiomyopathy, myopathy, growth retardation, neutropenia Cohen syndrome VPS13B AR Dysmorphism, deafness, mental retardation, obesity, neutropenia[arupconsult.com] (See Melanoma ) Esophageal and Esophagogastric Junction Cancers Gestational Trophoblastic Neoplasia Malignant Pleural Mesothelioma Melanoma Multiple Myeloma/Other Plasma[nccn.org] […] proximaldistal2 Neutropenia with decreased marrow reserve20 Neutropenia with normal marrow reserve20 Neutrophilia20 Nipple lesions Nodules painful Nystagmus Nystagmus monocular[books.google.com]

  • Rapp-Hodgkin Syndrome

    One showed growth retardation, craniofacial dysmorphism, syndactyly, developmental delay and a de novo deletion ( 8.5Mb) on chromosome 7q21.13-q21.3, including DLX5 and DLX6[ncbi.nlm.nih.gov] , cutaneous malignant, Renal cell carcinoma with or without malignant melanoma, Tietz albinism-deafness syndrome, Waardenburg syndrome MYO5A Griscelli syndrome OCA2 Albinism[genda.com.ar] Breast and/or nipple hypoplasia that may be symmetric or asymmetric is typically seen in ADULT syndrome and limb-mammary syndrome and not in other TP63- related disorders.[ncbi.nlm.nih.gov]

  • Aprosencephaly and Cerebellar Dysgenesis

    retardation-prognathism- cryptorchidism syndrome 3 Cases 25980 X-linked myopathy with excessive autophagy 15 Families 178461 X-linked myopathy with postural muscle atrophy[azkurs.org] Mesothelioma: 0.49, 0.78, 7.50, 8.00, 15.43, 62.50, 325.00, 434.00, 515.70, 655.20 Cancer: Melanoma: 0.49, 0.70, 32.80, 102.25, 212.75, 321.20, 434.00, 545.68, 795.61, 857.77[drhuldaclarkzappers.wordpress.com] Stevenson ; Introduction ; 33.1 Amastia-Hypomastia ; 33.2 Enlarged Breasts ; 33.3 Supernumerary Nipples ; 33.4 Widely Spaced Nipples ; 33.5 Gynecomastia ; Chapter 34 Asymmetric[geneeskundeboek.nl]

  • Ulnar Mammary Syndrome

    Characterized by diminished foetal activity, obesity, hypotonia, mental retardation, short stature, hypogonadotropichypogonadism, and small hands and feet Hyperphagia is a[slideshare.net] It is overexpressed in several cancers and may contributor to malignant melanoma.[sigmaaldrich.com] […] hypoplasia, asymmetrical features including unilateral ulnar or renal abnormalities).[ncbi.nlm.nih.gov]

  • Supernumerary Nipples

    , motor deficiency, growth failure and skin hypopigmentation (OMIM ID#309400).[infinitypath.com.au] melanoma, lymphangioma, osteoma cutis, and hypohidrosis.[e-ijd.org] Third nipple is found unilaterally and it can be symmetric or asymmetric. In some people it is found above the normal nipples and in other cases below.[diseasespictures.com]

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