Ataxia: Causes & Reasons

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Possible Causes for ataxia

Vitamin B12 Deficiency

A previously healthy 7-year-old Caucasian boy was hospitalised for evaluation of acute ataxia and failure to thrive, initially suspicious for an intracranial mass. [ncbi.nlm.nih.gov]

We describe a patient who manifested with acute onset of language dysfunction, chorea and ataxia. [ncbi.nlm.nih.gov]

We describe an elderly patient with vitamin B12 deficiency who presented cognitive dysfunction, peripheral polyneuropathy and sensory ataxia, and whose first clinical manifestation [ncbi.nlm.nih.gov]

Acute Alcohol Intoxication

The first patient (female, 50 years old) had dysarthria, nystagmus and trunk ataxia on admission. Her blood alcohol level was 2.3‰. [ncbi.nlm.nih.gov]

Alcohol intoxication is associated with central nervous system depression including unresponsiveness, hypothermia, and loss of gross motor control (ataxia, slurred speech) [medical-dictionary.thefreedictionary.com]

The patient with acute ethanol poisoning may present with symptoms ranging from slurred speech, ataxia and incoordination to coma, potentially resulting in respiratory depression [ncbi.nlm.nih.gov]

Alcohol Abuse

Recent FDA warning of metabolic acidosis, especially with renal or liver disease None Consider interactions withother anticonvulsant drugs. 53 Dizziness, somnolence, ataxia [aafp.org]

[…] contractures (also may be congenital) Testicular atrophy Enlarged or shrunken liver Enlarged spleen Complications of alcoholism manifest as follows: Wernicke encephalopathy: Ataxia [emedicine.medscape.com]

Adverse effects include dizziness and somnolence (which are not dose related), ataxia, impaired concentration, confusion, fatigue, paresthesias, speech difficulties, diplopia [aafp.org]

Pineal Gland Cyst

Less frequently, patients present with ataxia, motor and sensory impairment, mental and emotional disturbances, epilepsy, circadian rhythm disturbances, hypothalamic dysfunction [ncbi.nlm.nih.gov]

If narrowing of the cerebral aqueduct occurs, many neurological symptoms may exist, including headaches, vertigo, nausea, muscle fasciculations, eye sensitivity, and ataxia [en.wikipedia.org]

Peripheral Neuropathy

: Cerebellar ataxia and coeliac disease. Lancet 2004, 362 :1548. [doi.org]

Spinocerebellar ataxias (SCAs) are a group of autosomal dominant, clinically heterogeneous neurodegenerative disorders. [ncbi.nlm.nih.gov]

Vieira de Rezende Pinto, José Luiz Pedroso, Paulo Victor Sgobbi de Souza, Marcus Vinícius Cristino de Albuquerque and Orlando Graziani Povoas Barsottini, Non-progressive cerebellar [dx.doi.org]

Ménière Disease

Neurologic findings that are red flags include ataxia, skew, diplopia, cranial nerve abnormalities, visual field loss, and static imbalance,” says Rosenberg. [menieres-help.com]

Headache and ataxia may persist for days following an acute episode. [docneuro.com]

Hearing should be good in the opposite ear and there should be no ataxia. [audiologyonline.com]

Hyponatremia

Moderate - personality change, muscle cramps and weakness, confusion, ataxia. Severe - drowsiness. [patient.info]

24 Hours: 6-8 mEq/L ( Sterns 2010 ) DANGER : Rapid Overcorrection Rapid overcorrection of serum sodium can cause osmotic demyelination syndrome (ODS) ODS can manifest as ataxia [coreem.net]

Head Trauma

National Ataxia Foundation : Information, resources and support. [headinjury.com]

[…] flow to the tissue Aphasia – loss of the ability to express oneself and/or to understand language Arachnoid – middle layer of membranes covering the brain and spinal cord Ataxia [aans.org]

Stroke

The first patient (female, 50 years old) had dysarthria, nystagmus and trunk ataxia on admission. Her blood alcohol level was 2.3‰. [ncbi.nlm.nih.gov]

Dysarthria and right-sided limb ataxia were newly developed before DWI (after p-CTA). [ncbi.nlm.nih.gov]

He developed headache, nausea, vomiting, blurred vision, diplopia, dizziness, and ataxia following the procedure. [ncbi.nlm.nih.gov]

Cerebellar Stroke

After 3 months a mild ataxia in lower limbs and gait, especially in gait speed persisted. [ncbi.nlm.nih.gov]

This loss of muscle control and coordination, known as cerebellar ataxia, may affect both the limbs and the trunk of the body. [saebo.com]

Furthermore, acute cerebellar ataxia was not associated with a loss of the common drive. [ncbi.nlm.nih.gov]

Transient Ischemic Attack

The main clinical features of IHCP at presentation are headache, cranial nerve involvement, ataxia, and seizures. [ncbi.nlm.nih.gov]

Learn about Ataxia diagnosis, symptoms, causes and treatments at Northwell Health Institute for Neurology and Neurosurgery's Nerve Disorders Center. [northwell.edu]

[…] s disease: 20mins to hrs in combination with tinnitus, ear fullness or decreased hearing Vertigo History Features suggestive of posterior circulation ischemia: diplopia, ataxia [emergencymedicinecases.com]

Autoimmune Gastritis

Anemia Fatigue Neurological Shortness of breath Restless legs syndrome Peripheral neuropathy Dizziness Attentiveness disorder Myelopathy Tachycardia Brittle nails Spinal ataxia [ncbi.nlm.nih.gov]

[…] gastrointestinal and neurological complaints such as malabsorption, diarrhea, weight loss, glossitis, peripheral numbness, paresthesia with subsequent development of weakness, and ataxia [ncbi.nlm.nih.gov]

Chronic Alcoholism

There was a progressive development of parkinsonism, cerebellar ataxia, and mental deterioration by the time he was 32. [ncbi.nlm.nih.gov]

Others develop for non-hereditary reasons, such as alcoholic cerebellar ataxia. What Is Cerebellar Ataxia? Cerebellar ataxia is a symptom, not a distinct disorder. [promises.com]

[…] neuropathy) and central nervous sytem : Cognitive dysfunction, Cerebellar degeneration, Wernicke’s encephalopathy (acute reversible syndrome of psychosis, ophthalmoplegia, and ataxia [errolozdalga.com]

Subclavian Steal Syndrome

ataxias (ADCAs) and are characterized by ocular motor abnormalities, cognitive dysfunction, peripheral neuropathy, and progressive cerebellar ataxia. [frontiersin.org]

An overview of the patient with ataxia. J Neurol, 252 (2005), pp. 511-518 [11] A. Durr. Autosomal dominant cerebellar ataxias: polyglutamine expansions and beyond. [elsevier.es]

[…] time, stay the same or get slowly worse idiopathic late-onset cerebellar ataxia (ILOCA) – this usually begins at around 50 years of age and gets slowly worse over time ataxia [nhs.uk]

Progressive Myoclonic Epilepsy Type 7

Seizures or other neurological deficits, aside from mild cerebellar ataxia late in the course of the illness, are absent. [mendelian.co]

Dentatorubral-pallidoluysian atrophy  Rare autosomal-dominant neurodegenerative disorder, characterised by various combinations of cerebellar ataxia, choreoathetosis, myoclonus [slideshare.net]

ataxia Autosomal dominant cerebellar ataxia type I Autosomal dominant cerebellar ataxia type II Autosomal dominant cerebellar ataxia type III Autosomal dominant cerebellar [se-atlas.de]

Familial Infantile Myoclonic Epilepsy

ataxia. [mendelian.co]

Syndrome (FXTAS); Lysosomal Storage Diseases; Psychiatric Disorders; Dominant Spinocerebellar Ataxias; Metabolic Disorders; Friedreich Ataxia; ALS; Dementia; Neuromuscular [books.google.de]

Hunt Dentate Syndrome, Ataxia, Dentate Cerebellar, Ataxias, Dentate Cerebellar, Atrophies, Dentate Cerebellar, Atrophy, Dentate Cerebellar Myoclonic Epilepsies, Progressive [kmle.co.kr]

Primary Progressive Multiple Sclerosis

Abstract HDLS (Hereditary Diffuse Leukodystrophy with Spheroids) is a hereditary leukodystrophy whose main clinical manifestations include parkinsonism, spasticity, and ataxia [ncbi.nlm.nih.gov]

ICD-10-CM G35 is grouped within Diagnostic Related Group(s) (MS-DRG v 36.0): 058 Multiple sclerosis and cerebellar ataxia with mcc 059 Multiple sclerosis and cerebellar ataxia [icd10data.com]

Later in the course of the disease there may be extreme emotional lability, ataxia, abnormal reflexes, and difficulty in urinating. [medical-dictionary.thefreedictionary.com]

Basilar Migraine

Mutations in the CACNA1A gene on chromosome 19 have been associated with a variety of clinical disorders, including familial hemiplegic migraine type 1 and episodic ataxia [ncbi.nlm.nih.gov]

While additional cerebellar ataxia predominantly is associated with the FHM1 phenotype, all three are associated with epileptic phenomena. [repub.eur.nl]

In approximately 50% of FHM1 families, chronic progressive cerebellar ataxia occurs independently of the migraine attacks. [mdjunction.com]

Diabetes Mellitus Type 1

Progressive signs of ataxia in a eight years old girl prompted neurological investigation. [ncbi.nlm.nih.gov]

Her brother started to show ataxia at the age of 8 years and subsequent analysis also showed hypertrophic cardiomyopathy. [ncbi.nlm.nih.gov]

Kearns-Sayre syndrome Sporadic systemic disease, with progressive external ophthalmoplegia, retinal dystrophy, heart block, cerebellar ataxia and elevated protein levels in [scielo.br]

Posterior Inferior Cerebellar Artery Occlusion

ataxia Cerebellar ataxia Cerebellar ataxia Cerebellar ataxia Cerebellar Ataxia 2 Cerebellar Ataxia, Cayman Type Cerebellar Ataxia, Cayman Type Cerebellar Ataxia, Early-Onset [medical-dictionary.thefreedictionary.com]

ataxia and tremor Vascular, tumor Benedict Midbrain tegmentum III Red nucleus, corticospinal tract, brachium conjunctivum Oculomotor palsy, contralateral cerebellar ataxia [tchain.com]

Ipsilateral cerebellar ataxia. Why? Cerebellar peduncles affected. Inferior cerebellar peduncle in medullary and middle cerebellar peduncle in pons. [medicowesome.com]

Benzodiazepine Overdose

Ataxia was the most common clinical finding following benzodiazepine ingestion in this series. [doi.org]

Lethargy, slurred speech, ataxia, coma, and respiratory arrest may occur. [accessmedicine.mhmedical.com]

Isolated ataxia occurred in eight patients; in five of these patients, benzodiazepine ingestion was unsuspected by the physicians. [doi.org]

Hypotension

ataxia weight loss resting tachycardia or impaired heart rate variation abnormal GI motility erectile dysfunction and lack of ejaculation anhidrosis, heat intolerance, dry [online.epocrates.com]

Along with apathy with retained cognition, he had stable ataxia, impaired upgaze and episodes of central apnoea. [ncbi.nlm.nih.gov]

MSA is a progressive, adult-onset disorder characterized by a combination of autonomic dysfunction, parkinsonism, and ataxia. [emedicine.medscape.com]

Vertebrobasilar Insufficiency

Examination revealed a right third nerve palsy and ataxia. Symptoms and signs resolved over 24 hours. [aao.org]

Their symptoms included vertigo, dysarthria, dysphagia, syncope, motor and/or sensory disturbance, and cerebellar ataxia. Six had multiple stenotic lesions. [jstage.jst.go.jp]

The most common symptoms include: vertigo dizziness syncope diplopia visual field deficits blindness ataxia imbalance dysphagia dysarthria unilateral weakness Patient most [radiopaedia.org]

Zinc Deficiency

Neuropsychiatric signs include irritability, emotional instability, tremors, and occasional cerebellar ataxia. [doi.org]

[…] reported in Autism Spectrum Disorders (ASD), Attention deficit hyperactivity disorder (ADHD), Mood Disorders, such as depression, Schizophrenia (SCZ), and Spinocerebellar ataxia [dx.doi.org]

Infectious Mononucleosis

Infectious mononucleosis (IM) complicated with a neurological manifestation, including acute cerebellar ataxia, Guillain-Barre syndrome, meningitis, encephalitis, cranial [ncbi.nlm.nih.gov]

Ataxia Guillain-Barre syndrome Pancreatitis Myocarditis Pneumonia Lung disease Lymphocytosis Weakened immune system To find out more about these other possible illnesses, [americanpregnancy.org]

These include ataxia-telangiectasia, Chédiak-Higashi syndrome, Wiskott-Aldrich syndrome, and common variable immunodeficiency. [emedicine.medscape.com]

Cerebellar Hemorrhage

Thirty-two months later, he was readmitted with complaints of occipital, neck, and shoulder pain as well as cerebellar ataxia. [ncbi.nlm.nih.gov]

Neurological examination revealed left cerebellar ataxia. Neuroimaging showed multiple cerebellar metastases with cerebellar hemorrhage adjacent to the tentorium. [ncbi.nlm.nih.gov]

Susac Syndrome

The encephalopathy, ataxia, and urinary incontinence resolved, and the hearing loss stabilized. [onlinelibrary.wiley.com]

All cases manifested varied neurological symptoms including pyramidal and/or sensory tract symptoms, amnesic disorders, ataxia and vertigo. [ncbi.nlm.nih.gov]

(Friedreich's ataxia, Ataxia telangiectasia, Hereditary spastic paraplegia) Spinal muscular atrophy: Werdnig-Hoffman - Kugelberg-Welander - Fazio Londe - MND (ALS, PMA, PBP [wikidoc.org]

Pernicious Anemia

We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia [ncbi.nlm.nih.gov]

The outcome was rapidly marked by febrile pancytopenia and ataxia leading to the diagnosis of pernicious anemia. [ncbi.nlm.nih.gov]

[…] and included sore mouth, pallor, paresthesias, the Lhermitte symptom, fever, headaches, fatigue, resting tachycardia, edema, episodic weight loss, progressive weakness, ataxia [ncbi.nlm.nih.gov]

Opiate Overdose

Abstract Heroin and other opiates are central nervous system depressants; in an opiate overdose, respiration slows, potentially resulting in hypoxia, coma, or death. In 1998, 140 deaths from unintentional opiate overdoses occurred in King County (which includes Seattle). To characterize these deaths, public health[…] [ncbi.nlm.nih.gov]

Hypothyroidism

Hypothyroidism should be considered in all cases of cerebellar ataxia as it is a reversible cause of ataxia. [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

ataxia PSYCHE: Depression SKIN: Dry skin, pale, course dry hair, brittle nails, hair loss, and temporal thinning of eyebrows Differential diagnosis for hypothyroidism includes [uth.tmc.edu]

Cerebellar ataxia. Psychosis. Encephalopathy. Patients can go on to develop myxoedema coma (see below). [patient.info]