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535 Possible Causes for Ataxia, Emotional Lability, Parkinson's Disease

  • Progressive Supranuclear Palsy

    lability and freezing of gait.[pacificneuroscienceinstitute.org] His principal symptom was cerebellar ataxia for several years.[ncbi.nlm.nih.gov] P/M, pons to midbrain ratio; PD, idiopathic Parkinson's disease; PSP-RS, Progressive Supranuclear Palsy-Richardson's Syndrome; Parkinson's disease; Progressive Supranuclear[ncbi.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis

    Emotional Lability in MND: relationship to cognition and psychopathology and impact on caregivers. J. Neurol. Sci. 278, 16–20.[dx.doi.org] Blood from ND patients with PD, ALS and Ataxia with movement dysfunctions were obtained to analyse mRNA and protein expressions of the above mentioned factors in lymphocytes[ncbi.nlm.nih.gov] Amyotrophic lateral sclerosis (ALS) and Parkinson's disease, both progressive neurodegenerative diseases, affect 1 million Americans (1,2).[ncbi.nlm.nih.gov]

  • Creutzfeldt Jakob Disease

    Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding.[ncbi.nlm.nih.gov] Jellinger KA (2000) Cell death mechanisms in Parkinson’s disease. J Neural Transm 107:1–29 PubMed CrossRef Google Scholar 32.[dx.doi.org] We report a Japanese patient with spinocerebellar ataxia type 31 (SCA31) and sporadic Creutzfeldt-Jakob disease (sCJD).[ncbi.nlm.nih.gov]

  • Huntington's Disease

    Presentation is typically with progressive rigidity, choreoathetosis, dementia, psychosis and emotional lability 2 .[radiopaedia.org] We screened 89 patients with a Huntington's disease-like phenotype without the HD-gene mutation and 178 patients with genetically unclassified cerebellar ataxia for the mutation[ncbi.nlm.nih.gov] Box B Parkinson's Disease: An Opportunity for Novel Therapeutic Approaches.[ncbi.nlm.nih.gov]

  • Primary Progressive Multiple Sclerosis

    Later in the course of the disease there may be extreme emotional lability, ataxia, abnormal reflexes, and difficulty in urinating.[medical-dictionary.thefreedictionary.com] Spastic paraparesis and progressive ataxia are principal symptoms in this subset of patients.[symptoma.com] Abstract We report a patient with young onset Parkinson's disease (PD) and a heterozygous point mutation in parkin (c.1000C T; p.Arg334Cys).[ncbi.nlm.nih.gov]

  • Shy Drager Syndrome

    Patients frequently note emotional lability, with short (sometimes only one or two minutes) episodes of crying due to happiness or sadness in response to relatively minor[mc.vanderbilt.edu] “Probable MSA” requires autonomic failure/urinary dysfunction plus poorly responsive parkinsonism or cerebellar ataxia.[journals.lww.com] disease.[ncbi.nlm.nih.gov]

  • Stroke

    Emotional lability occurs in about 20% of those who have had a stroke.[en.wikipedia.org] The first patient (female, 50 years old) had dysarthria, nystagmus and trunk ataxia on admission. Her blood alcohol level was 2.3‰.[ncbi.nlm.nih.gov] Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study , A J Yarnall , R A Lawson , G W Duncan , T K Khoo , G S Petrides , J T O'Brien[jnnp.bmj.com]

  • Olivopontocerebellar Atrophy

    She developed a mild dementia characterized by mild memory disturbance with preservation of orientation, slowing of thought processes, emotional lability toward sadness, impaired[ncbi.nlm.nih.gov] Spinocerebellar ataxia type 6 (SCA6) is an autosomal dominant, slowly progressive cerebellar ataxia without multisystem involvement.[ncbi.nlm.nih.gov] Abstract Nine Parkinson's disease (PD), seven olivopontocerebellar atrophy (OPCA) patients and two age-matched control groups learned a linear arm movement-scaling task over[ncbi.nlm.nih.gov]

  • Brain Neoplasm

    Symptoms of pediatric posterior fossa tumors include increased irritability, unsteadiness, ataxia, headache, vomiting, and progressive obtundation.[emedicine.medscape.com] Disease: 13 people, 46.43% Osteoporosis (bones weak and more likely to break): 13 people, 46.43% Osteopenia (a condition where bone mineral density is lower than normal):[ehealthme.com] Manifestations may be nonspecific and include the following: Headache Altered mental status Ataxia Nausea Vomiting Weakness Gait disturbance CNS neoplasms also may manifest[emedicine.medscape.com]

  • Multiple Sclerosis

    Vertigo, incoordination and other cerebellar problems, depression, emotional lability, abnormalities in gait, dysarthria, fatigue and pain are also commonly seen.[library.med.utah.edu] ‘Medusa head ataxia’: The expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia.[journals.sagepub.com] [ 54 ], and patients with Parkinson’s disease [ 55 ].[journals.plos.org]

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