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244 Possible Causes for Ataxia, Muscle Twitch, Spasticity - Hyperreflexia

  • Hallervorden-Spatz Syndrome

    Described features include 9,11 : progressive dementia extrapyramidal signs (rigidity, dystonia, choreoathetosis) corticospinal signs (spasticity, hyperreflexia) dysarthria[radiopaedia.org] The patient presented with a slowly progressive illness with seizures, extrapyramidal symptoms, cerebellar ataxia, dementia, spasticity, myoclonic movements and a severe demyelinating[ncbi.nlm.nih.gov] They may experience involuntary muscle contractions (dystonia) of the head and neck, resulting in repetitive movements and contortions.[ghr.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis

    The upper motor signs include spasticity, hyperreflexia and weakness. The lower motor signs include amyotrophy, weakness and fasciculations.[symptoma.com] Blood from ND patients with PD, ALS and Ataxia with movement dysfunctions were obtained to analyse mRNA and protein expressions of the above mentioned factors in lymphocytes[ncbi.nlm.nih.gov] twitching for 3 years.[ncbi.nlm.nih.gov]

  • Primary Progressive Multiple Sclerosis

    Affected individuals may have tremors, muscle stiffness (spasticity), exaggerated reflexes (hyperreflexia), weakness or partial paralysis of the muscles of the limbs, difficulty[icdlist.com] Spastic paraparesis and progressive ataxia are principal symptoms in this subset of patients.[symptoma.com] Abstract HDLS (Hereditary Diffuse Leukodystrophy with Spheroids) is a hereditary leukodystrophy whose main clinical manifestations include parkinsonism, spasticity, and ataxia[ncbi.nlm.nih.gov]

  • Spastic Paraparesis-Deafness Syndrome

    , hyperreflexia, urinary bladder disturbance (hypertonic bladder) and extensor plantar responses with weakness of a pyramidal distribution in the lower limbs.[ruralneuropractice.com] II Dominant non-episodic cerebellar ataxia Familial periventricular heterotopia Gilles de la Tourette syndrome Hereditary progressive hearing loss Hereditary spastic paraplegia[academic.oup.com] Apraxia (Medical Encyclopedia) Hand or foot spasms (Medical Encyclopedia) Muscle atrophy (Medical Encyclopedia) Muscle function loss (Medical Encyclopedia) Muscle twitching[icdlist.com]

  • Shy Drager Syndrome

    , hyperreflexia, and Babinski sign), cognitive impairment, visual hallucinations, and REM sleep behavior disorder (RBD).[doi.org] “Probable MSA” requires autonomic failure/urinary dysfunction plus poorly responsive parkinsonism or cerebellar ataxia.[journals.lww.com] […] all parts of the body loud snoring, abnormal breathing or inspiratory stridor during sleep other sleep disorders including sleep apnea, REM behavior disorderdouble vision muscle[en.wikipedia.org]

  • Creutzfeldt Jakob Disease

    Clinical features of sCJD include myoclonic jerks, memory deficits, cerebellar signs (ataxia, nystagmus, tremors), pyramidal/corticospinal tract dysfunctions (spasticity,[doi.org] Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is a very rare finding.[ncbi.nlm.nih.gov] Startling may trigger muscle twitching. The muscles that control breathing and coughing are usually impaired, increasing the risk of pneumonia.[web.archive.org]

  • Upper Motor Neuron Disease

    No spasticity or hyperreflexia.[brainscape.com] G11.1 Early-onset cerebellar ataxia G11.2 Late-onset cerebellar ataxia G11.3 Cerebellar ataxia with defective DNA repair G11.4 Hereditary spastic paraplegia G11.8 Other hereditary[icd10data.com] Lower motor neuron disease causes weakness, loss of muscle ("atrophy") and muscle twitching ("fasciculations").[neurology.emory.edu]

  • Paraplegia

    This development led to an evaluation by a neurosurgeon, who noted spasticity and hyperreflexia. Sensory testing demonstrated a possible sensory thoracic level.[medscape.com] No other known SPG, myokymia, or ataxia-related genes harbored clinically relevant variants (table e-3).[ng.neurology.org] , but also to cause muscle hypertrophy and muscle fibre shift from fast twitch type 2X to 2A. 3 In addition to these effects, oxidative enzyme activity has also been shown[bjsm.bmj.com]

  • Machado-Joseph Disease

    MJD Type 1 patients generally present with cerebellar signs and external progressive ophthalmoplegia with variable degrees of pyramidal manifestations (spasticity, hyperreflexia[orpha.net] Cerebellar Ataxia Rehabilitation Trialists Collaboration. Cerebellar ataxia rehabilitation trial in degenerative cerebellar diseases.[ncbi.nlm.nih.gov] As symptoms arise, medications are typically prescribed for sleep problems, muscle twitching, urinary dysfunction and cramping.[babymed.com]

  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[aafp.org] Moderate - personality change, muscle cramps and weakness, confusion, ataxia. Severe - drowsiness.[patient.info] As hyponatremia becomes more severe, muscle twitching and seizures may occur.[merckmanuals.com]

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